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Antiplatelet and Antithrombotic Properties of Compound L-36, a 6H-1,3,4-Thiadiazine Derivative
Compound L-36, a new derivative of 6 H -1,3,4-thiadiazine, was studied in in vitro and in vivo experiments. This compound exhibits high antiplatelet...
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Diagnostic criteria for optic neuritis in the acute and subacute phase: clinical uses and limitations
BackgroundA recent international consensus panel proposed diagnostic criteria for optic neuritis and a new classification. We aimed to investigate...
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Culturally Centered Palliative Care: A Framework for Equitable Neurocritical Care
Health disparities continue to plague racial and ethnic underserved patients in the United States. Disparities extend to the most critically ill...
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French National Protocol for diagnosis and care of facioscapulohumeral muscular dystrophy (FSHD)
Facioscapulohumeral muscular dystrophy (FSHD) is one of the most common genetically inherited myopathies in adults. It is characterized by incomplete...
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Effects of a Hydrolyzed Lignin Derivative on Bleomycin-Induced Pulmonary Fibrosis in Mice
Female C57BL/J mice with pulmonary fibrosis induced by injections of bleomycin (20 mg/kg intraperitoneally, 8 times for 4 weeks) were treated with a...
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Static and temporal dynamic alterations of regional homogeneity in chronic insomnia: a resting-state fMRI study
To explore brain function alterations in chronic insomnia (CI). 65 CI patients and 48 healthy controls were included to analyze abnormal alterations...
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Ectonucleotidase Activity in Smooth Muscle Tissues of Rats with a Valproate Model of Autism
Ectonucleotidases play an important role in regulating the level of extracellular nucleotides and nucleosides and are an important part of the...
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Cerebrospinal Creatine Kinase BB Isoenzyme: A Biomarker for Predicting Outcome After Cardiac Arrest
BackgroundCerebrospinal fluid creatine kinase BB isoenzyme (CSF CK-BB) after cardiac arrest (CA) has been shown to have a high positive predictive...
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Pioneers of cortical cytoarchitectonics: the forgotten contribution of Herbert Major
The study of cortical cytoarchitectonics and the histology of the human cerebral cortex was pursued by many investigators in the second half of the...
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Management of external ventricular drain: to wean or not to wean?
PurposeExternal ventricular drain (EVD) is one of the most frequent procedures in neurosurgery and around 15 to 30% of these patients require a...
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Intermittent hypoxia exacerbates anxiety in high-fat diet-induced diabetic mice by inhibiting TREM2-regulated IFNAR1 signaling
BackgroundType 2 diabetes mellitus (T2DM) and obstructive sleep apnea (OSA) are mutual risk factors, with both conditions inducing cognitive...
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Safety and Outcome of Admission to Step-Down Level of Care in Patients with Low-Risk Spontaneous Intracerebral Hemorrhage: A Systematic Review and Meta-analysis
Spontaneous intracerebral hemorrhage (ICH) is the most devastating type of stroke, and it is associated with high morbidity and mortality. Patients...
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Admission Viscoelastic Hemostatic Assay Parameters Predict Poor Long-Term Intracerebral Hemorrhage Outcomes
BackgroundViscoelastic hemostatic assays (VHAs) provide more comprehensive assessments of coagulation compared with conventional coagulation assays....
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Single-nucleus multi-omics of Parkinson’s disease reveals a glutamatergic neuronal subtype susceptible to gene dysregulation via alteration of transcriptional networks
The genetic architecture of Parkinson’s disease (PD) is complex and multiple brain cell subtypes are involved in the neuropathological progression of...
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Integration of Family Navigation into ECHO Autism for Pediatric Primary Care in Underserved Communities
Children with autism from underserved communities face complex system-, provider-, and family-level barriers to accessing timely diagnosis and early...
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Investigation of Menstrual Hygiene and Self-Care Skills of Adolescent Girls with Autism Spectrum Disorder: Mother Views
PurposePuberty a period of transition from childhood to adulthood, poses problems that are difficult to manage for typically develo** adolescents,...
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Effect of Early Inhibition of Toll-Like Receptor 4 on Hippocampal Plasticity in a Neonatal Rat Model of Hypoxic-Ischemic Brain Damage
Hippocampal plasticity is closely related to physiological brain functions such as learning and memory. However, the effect of toll-like receptor 4...
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Exploring the profiles of foreign language learners’ writing self-regulation: focusing on individual differences
The available classifications of self-regulated learners may not be applicable to second or foreign language writing due to the contextual nature of...
