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  1. Regulation of IP 3 Receptors by IP 3 and Ca 2+

    Inositol 1,4,5-trisphosphate ( IP 3) receptors are intracellular Ca 2+ channels that mediate release of Ca 2+ from intracellular stores. The channels...
    Colin W. Taylor, Jane E. Swatton in Understanding Calcium Dynamics
    Chapter
  2. Modeling Calcium Waves

    We present an introduction to the mathematics of calcium waves, both intracellular and intercellular. After a discussion of the earlier models I...
    James Sneyd, Krasimira Tsaneva-Atanasova in Understanding Calcium Dynamics
    Chapter
  3. Hormone-Mediated Intercellular Calcium Signalling in an Insect Salivary Gland – Pathways and Mechanisms

    The salivary glands of the blowfly Calliphora vicina are a favourable preparation for investigations into spatio-temporal Ca 2+ dynamics in an intact...
    Bernhard Zimmermann, Bernd Walz in Understanding Calcium Dynamics
    Chapter
  4. From Simple to Complex Ca 2+ Oscillations: Regulatory Mechanisms and Theoretical Models

    Intracellular Ca 2+ oscillations most often appear as regular spikes. However, complex Ca 2+ oscillations in the form of bursting or chaos have also...
    G. Dupont, G. Houart, A. Goldbeter in Understanding Calcium Dynamics
    Chapter
  5. Introduction: Regulatory processes, an emerging feature in intracellular membrane traffic

    The subject of this volume is the molecular mechanism of the intracellular membrane trafficking, a central eukaryotic cell biological process. In the...
    Chapter
  6. Synthetic Musks in Bioindicators: Monitoring Data of Fish and Human Milk Samples from the Czech Republic

    Until the middle of the 1990s, no attention was paid to the pollution of the environment in Czech Republic by synthetic musk fragrances and to the...
    Jana Hajšlová, Lucie Šetková in Series Anthropogenic Compounds
    Chapter
  7. Risk Evaluation of Dietary and Dermal Exposure to Musk Fragrances

    Synthetic musk compounds comprising nitro musks, polycyclic musks and macrocyclic musks are used in fragrances which are added to a variety of...
    Premysl Slanina in Series Anthropogenic Compounds
    Chapter
  8. Biotic and Abiotic Transformation Pathways of Synthetic Musks in the Aquatic Environment

    Synthetic musks are being transformed to intermediates or relatively stable metabolites that may exhibit a strong potential for environmental harm....
    Scarlett Biselli, Robert Gatermann, ... Heinrich Hühnerfuss in Series Anthropogenic Compounds
    Chapter
  9. Synthetic Musks in Suspended Particulate Matter (SPM), Sediment, and Sewage Sludge

    Nitro musk and polycyclic musk fragrances accumulate in solid matters of the aquatic environment. They are analyzed by extraction with an organic...
    Cornelia Fooken in Series Anthropogenic Compounds
    Chapter
  10. Enantioselective Analysis of Polycyclic Musks as a Versatile Tool for the Understanding of Environmental Processes

    In this chapter the application of enantioselective chromatography to process studies related to the microbial, enzymatic and photochemical...
    Heinrich Hühnerfuss, Scarlett Biselli, Robert Gatermann in Series Anthropogenic Compounds
    Chapter
  11. Functions of Rab GTPases in organelle biogenesis

    Rab GTPases regulate diverse aspects of the biogenesis of secretory and endocytic organelles. The conformational changes that accompany GTP binding...
    Christopher G. Burd, Ruth N. Collins in Regulatory Mechanisms of Intracellular Membrane Transport
    Chapter
  12. The Endoplasmic Reticulum: A Central Player in Cell Signalling and Protein Synthesis

    In addition to being the principle intracellular Ca 2+ store, the endoplasmic reticulum (ER) is the initial site of synthesis and folding of membrane...
    H. Llewelyn Roderick, Michael J. Berridge, Martin D. Bootman in Understanding Calcium Dynamics
    Chapter
  13. Global and Local Regulation of Neuronal Differentiation by Calcium Transients

    Embryonic spinal neurons express ion channels prior to synaptogenesis that mediate specialized forms of excitability promoting Ca 2+ influx. Ca 2+...
    Nicholas C. Spitzer in Understanding Calcium Dynamics
    Chapter
  14. Role of NAADP in Coordinating Spatiotemporal Aspects of Calcium Signalling

    We outline the roles of two low molecular weight phosphorylated compounds as intracellular messengers in calcium signaling. These new intracellular...
    Grant C. Churchill, Antony Galione in Understanding Calcium Dynamics
    Chapter
  15. Mitochondrial and ER Calcium Uptake and Release Fluxes and their Interplay in Intact Nerve Cells

    Ionized free Ca ( Ca 2+) is a ubiquitous signaling ion that serves as the critical link between a variety of physiological stimuli and their...
    David D. Friel in Understanding Calcium Dynamics
    Chapter
  16. Building a Wave – Models of the Puff-to-Wave Transition

    Ca2+ release channels open and close randomly because of random binding and dissociation of Ca2+ and IP3 to their subunits. They are arranged in...
    Chapter
  17. The Role of Musk and Musk Compounds in the Fragrance Industry

    An overview of the role of musk and musk compounds in the fragrance industry is given. Discovery and syntheses of representatives occurring naturally...
    Cornelia Sommer in Series Anthropogenic Compounds
    Chapter
  18. Regulation of SNARE assembly by protein phosphorylation

    Protein phosphorylation is emerging as an important regulatory mechanism that controls the secretory pathway. It enables coupling between the...
    Adina Weinberger, Jeffrey E. Gerst in Regulatory Mechanisms of Intracellular Membrane Transport
    Chapter
  19. Molecular mechanisms in clathrin-mediated membrane budding

    Clathrin-coated vesicles (CCVs) form at the plasma membrane where they select cargo for endocytic entry into cells. CCVs also form at the trans-Golgi...
    Brigitte Ritter, Peter S. McPherson in Regulatory Mechanisms of Intracellular Membrane Transport
    Chapter
  20. Tethering proteins in membrane traffic

    In eukaryotic cells, protein secretion and the transport of materials between membrane-bounded organelles require efficient and accurate delivery of...
    Chapter
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