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Regulation of IP 3 Receptors by IP 3 and Ca 2+
Inositol 1,4,5-trisphosphate ( IP 3) receptors are intracellular Ca 2+ channels that mediate release of Ca 2+ from intracellular stores. The channels... -
Modeling Calcium Waves
We present an introduction to the mathematics of calcium waves, both intracellular and intercellular. After a discussion of the earlier models I... -
Hormone-Mediated Intercellular Calcium Signalling in an Insect Salivary Gland – Pathways and Mechanisms
The salivary glands of the blowfly Calliphora vicina are a favourable preparation for investigations into spatio-temporal Ca 2+ dynamics in an intact... -
From Simple to Complex Ca 2+ Oscillations: Regulatory Mechanisms and Theoretical Models
Intracellular Ca 2+ oscillations most often appear as regular spikes. However, complex Ca 2+ oscillations in the form of bursting or chaos have also... -
Introduction: Regulatory processes, an emerging feature in intracellular membrane traffic
The subject of this volume is the molecular mechanism of the intracellular membrane trafficking, a central eukaryotic cell biological process. In the... -
Synthetic Musks in Bioindicators: Monitoring Data of Fish and Human Milk Samples from the Czech Republic
Until the middle of the 1990s, no attention was paid to the pollution of the environment in Czech Republic by synthetic musk fragrances and to the... -
Risk Evaluation of Dietary and Dermal Exposure to Musk Fragrances
Synthetic musk compounds comprising nitro musks, polycyclic musks and macrocyclic musks are used in fragrances which are added to a variety of... -
Biotic and Abiotic Transformation Pathways of Synthetic Musks in the Aquatic Environment
Synthetic musks are being transformed to intermediates or relatively stable metabolites that may exhibit a strong potential for environmental harm.... -
Synthetic Musks in Suspended Particulate Matter (SPM), Sediment, and Sewage Sludge
Nitro musk and polycyclic musk fragrances accumulate in solid matters of the aquatic environment. They are analyzed by extraction with an organic... -
Enantioselective Analysis of Polycyclic Musks as a Versatile Tool for the Understanding of Environmental Processes
In this chapter the application of enantioselective chromatography to process studies related to the microbial, enzymatic and photochemical... -
Functions of Rab GTPases in organelle biogenesis
Rab GTPases regulate diverse aspects of the biogenesis of secretory and endocytic organelles. The conformational changes that accompany GTP binding... -
The Endoplasmic Reticulum: A Central Player in Cell Signalling and Protein Synthesis
In addition to being the principle intracellular Ca 2+ store, the endoplasmic reticulum (ER) is the initial site of synthesis and folding of membrane... -
Global and Local Regulation of Neuronal Differentiation by Calcium Transients
Embryonic spinal neurons express ion channels prior to synaptogenesis that mediate specialized forms of excitability promoting Ca 2+ influx. Ca 2+... -
Role of NAADP in Coordinating Spatiotemporal Aspects of Calcium Signalling
We outline the roles of two low molecular weight phosphorylated compounds as intracellular messengers in calcium signaling. These new intracellular... -
Mitochondrial and ER Calcium Uptake and Release Fluxes and their Interplay in Intact Nerve Cells
Ionized free Ca ( Ca 2+) is a ubiquitous signaling ion that serves as the critical link between a variety of physiological stimuli and their... -
Building a Wave – Models of the Puff-to-Wave Transition
Ca2+ release channels open and close randomly because of random binding and dissociation of Ca2+ and IP3 to their subunits. They are arranged in... -
The Role of Musk and Musk Compounds in the Fragrance Industry
An overview of the role of musk and musk compounds in the fragrance industry is given. Discovery and syntheses of representatives occurring naturally... -
Regulation of SNARE assembly by protein phosphorylation
Protein phosphorylation is emerging as an important regulatory mechanism that controls the secretory pathway. It enables coupling between the... -
Molecular mechanisms in clathrin-mediated membrane budding
Clathrin-coated vesicles (CCVs) form at the plasma membrane where they select cargo for endocytic entry into cells. CCVs also form at the trans-Golgi... -
Tethering proteins in membrane traffic
In eukaryotic cells, protein secretion and the transport of materials between membrane-bounded organelles require efficient and accurate delivery of...