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  1. Cholera toxin: mechanisms of entry into host cells

    Cholera toxin moves from the plasma membrane to the ER of host cells to cause disease. Trafficking in this pathway depends on toxin binding to...
    David E. Saslowsky, Michael Kothe, Wayne I. Lencer in Microbial Protein Toxins
    Chapter
  2. The Ustilago maydis killer toxins

    Killer toxins are small proteins secreted by a number of fungi that are lethal to susceptible cells (generally fungi of the same or related species)....
    Jeremy Bruenn in Microbial Protein Toxins
    Chapter
  3. Deconvolution Microscopy

    Since its introduction in 1983, deconvolution microscopy has become a key image-processing tool for visualizing the cellular structures of fixed and...
    Jean-Baptiste Sibarita in Microscopy Techniques
    Chapter
  4. S. cerevisiae K28 toxin – a secreted virus toxin of the A/B family of protein toxins

    Since the initial discovery of toxin-secreting killer strains in the yeast Saccharomyces cerevisiae more than 40 years ago, continuous research on...
    Susanne Leis, Jenny Spindler, ... Manfred J. Schmitt in Microbial Protein Toxins
    Chapter
  5. Total Internal Reflection Fluorescence Microscopy in Single Molecule Nanobioscience

    Recent development in total internal reflection fluorescence microscopy (TIRFM) has made it possible to directly monitor the behaviors of...
    Tetsuichi Wazawa, Masahiro Ueda in Microscopy Techniques
    Chapter
  6. Tracking Movement in Cell Biology

    This article is an overview of techniques for measuring movement of proteins, vesicles and cells using digital image processing. Diverse techniques...
    Kota Miura in Microscopy Techniques
    Chapter
  7. Regeneration of Articular Cartilage

    Loss of articular cartilage from the ends of bones forming diarthrodial joints can be the source of profound pain and disability, and eventually lead...
    B. Kinner, R. M. Capito, M. Spector in Regenerative Medicine II
    Chapter
  8. Fluorescence Lifetime Imaging Microscopy (FLIM)

    Fluorescence lifetime imaging microscopy (FLIM) is a technique to map the spatial distribution of nanosecond excited state lifetimes within...
    Erik B. van Munster, Theodorus W. J. Gadella in Microscopy Techniques
    Chapter
  9. Spectral Imaging and Linear Unmixing in Light Microscopy

    Fluorescence microscopy is an essential tool for modern biological research. The wide range of available fluorophores and labeling techniques allows...
    Timo Zimmermann in Microscopy Techniques
    Chapter
  10. Diphtheria toxin, diphtheria-related fusion protein toxins, and the molecular mechanism of their action against eukaryotic cells

    Diphtheria toxin remains one of the most successfully studied of the bacterial protein toxins. A detailed understanding of the structure function...
    Ryan Ratts, John R. Murphy in Microbial Protein Toxins
    Chapter
  11. Vertebrate Limb Regeneration

    In this chapter, we have touched upon some of the key processes of vertebrate limb regeneration from the formation of the wound epithelium to pattern...
    Mindy K. Call, Panagiotis A. Tsonis in Regenerative Medicine I
    Chapter
  12. Mammalian Fetal Organ Regeneration

    The develo** fetus has the remarkable ability to heal dermal skin wounds by regenerating normal epidermis and dermis with restoration of the...
    Amy S. Colwell, Michael T. Longaker, H. Peter Lorenz in Regenerative Medicine I
    Chapter
  13. Regenerative Capacity and the Develo** Immune System

    Many components of the vertebrate immune system have evolved with dual, interrelated functions of both protecting injured tissues from infection and...
    Anthony L. Mescher, Anton W. Neff in Regenerative Medicine I
    Chapter
  14. Tissue Engineering Strategies for Bone Regeneration

    Bone loss due to trauma or disease is an increasingly serious health problem. Current clinical treatments for critical-sized defects are problematic...
    Amit S. Mistry, Antonios G. Mikos in Regenerative Medicine II
    Chapter
  15. Stem Cells in CNS and Cardiac Regeneration

    The central nervous system (CNS) and the heart muscle regenerate poorly after injury, yet evidence is mounting that both harbor cells capable of...
    David L. Stocum in Regenerative Medicine I
    Chapter
  16. Degradation and Preservation of Organic Matter in Marine Sediments

    Organic matter that is deposited in aquatic sediments is subject to an intense diagenetic reactor that determines how much organic carbon is...
    Stuart G. Wakeham, Elizabeth A. Canuel in Marine Organic Matter: Biomarkers, Isotopes and DNA
    Chapter
  17. The Material-Independent Signatures of Life.Forensic Tools of Astrobiology

    Biological life is intimately related to the geochemical conditions on Earth and is fit for this planet’s energy flux. It has often been suggested...
    Chapter
  18. The Early History of Bioenergy

    Energy is most commonly defined as the potential to do work. The maintenance of the living state requires a constant flow of energy through the...
    Chapter
  19. Assembling the Early Puzzle of Life

    So far no theory, no approach, no set of formulas, and no blackboard scheme have been found satisfactory in explaining the origin of life. The...
    Chapter
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