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Cholera toxin: mechanisms of entry into host cells
Cholera toxin moves from the plasma membrane to the ER of host cells to cause disease. Trafficking in this pathway depends on toxin binding to... -
The Ustilago maydis killer toxins
Killer toxins are small proteins secreted by a number of fungi that are lethal to susceptible cells (generally fungi of the same or related species).... -
Deconvolution Microscopy
Since its introduction in 1983, deconvolution microscopy has become a key image-processing tool for visualizing the cellular structures of fixed and... -
S. cerevisiae K28 toxin – a secreted virus toxin of the A/B family of protein toxins
Since the initial discovery of toxin-secreting killer strains in the yeast Saccharomyces cerevisiae more than 40 years ago, continuous research on... -
Total Internal Reflection Fluorescence Microscopy in Single Molecule Nanobioscience
Recent development in total internal reflection fluorescence microscopy (TIRFM) has made it possible to directly monitor the behaviors of... -
Tracking Movement in Cell Biology
This article is an overview of techniques for measuring movement of proteins, vesicles and cells using digital image processing. Diverse techniques... -
Regeneration of Articular Cartilage
Loss of articular cartilage from the ends of bones forming diarthrodial joints can be the source of profound pain and disability, and eventually lead... -
Fluorescence Lifetime Imaging Microscopy (FLIM)
Fluorescence lifetime imaging microscopy (FLIM) is a technique to map the spatial distribution of nanosecond excited state lifetimes within... -
Spectral Imaging and Linear Unmixing in Light Microscopy
Fluorescence microscopy is an essential tool for modern biological research. The wide range of available fluorophores and labeling techniques allows... -
Diphtheria toxin, diphtheria-related fusion protein toxins, and the molecular mechanism of their action against eukaryotic cells
Diphtheria toxin remains one of the most successfully studied of the bacterial protein toxins. A detailed understanding of the structure function... -
Vertebrate Limb Regeneration
In this chapter, we have touched upon some of the key processes of vertebrate limb regeneration from the formation of the wound epithelium to pattern... -
Mammalian Fetal Organ Regeneration
The develo** fetus has the remarkable ability to heal dermal skin wounds by regenerating normal epidermis and dermis with restoration of the... -
Regenerative Capacity and the Develo** Immune System
Many components of the vertebrate immune system have evolved with dual, interrelated functions of both protecting injured tissues from infection and... -
Tissue Engineering Strategies for Bone Regeneration
Bone loss due to trauma or disease is an increasingly serious health problem. Current clinical treatments for critical-sized defects are problematic... -
Stem Cells in CNS and Cardiac Regeneration
The central nervous system (CNS) and the heart muscle regenerate poorly after injury, yet evidence is mounting that both harbor cells capable of... -
Degradation and Preservation of Organic Matter in Marine Sediments
Organic matter that is deposited in aquatic sediments is subject to an intense diagenetic reactor that determines how much organic carbon is... -
The Material-Independent Signatures of Life.Forensic Tools of Astrobiology
Biological life is intimately related to the geochemical conditions on Earth and is fit for this planet’s energy flux. It has often been suggested... -
The Early History of Bioenergy
Energy is most commonly defined as the potential to do work. The maintenance of the living state requires a constant flow of energy through the... -
Assembling the Early Puzzle of Life
So far no theory, no approach, no set of formulas, and no blackboard scheme have been found satisfactory in explaining the origin of life. The...