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Reallocating just 10 min to moderate-to-vigorous physical activity from other components of 24-hour movement behaviors improves cardiovascular health in adults
BackgroundAs components of a 24-hour day, sedentary behavior (SB), physical activity (PA), and sleep are all independently linked to cardiovascular...
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Biomarkers In Prediction of Acute Mesenteric Ischaemia: a prospective multicentre study (BIPAMI study): a study protocol
BackgroundAcute mesenteric ischaemia (AMI) is a life-threatening disease where early diagnosis is critical to avoid morbidity and mortality from...
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Treatment Strategies for Filamentous Fungi Keratitis
IntroductionThis research aims to describe clinical findings, epidemiology and treatment outcomes in patients with filamentous fungi keratitis of a...
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Insomnia During Late Life: Potential Pathways Toward Suicide Risk
Purpose of ReviewAs the global population continues to age, the identification of drivers of suicide risk in older adults is of increasing...
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Semaphorin 3C (Sema3C) reshapes stromal microenvironment to promote hepatocellular carcinoma progression
More than 90% of hepatocellular carcinoma (HCC) cases develop in the presence of fibrosis or cirrhosis, making the tumor microenvironment (TME) of...
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Prolonged water-only fasting in the management of low-grade follicular lymphoma: a case series
BackgroundFollicular lymphoma typically follows an indolent and relapsing course often requiring several treatment cycles to achieve remission. Some...
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In silico exploration of anti-prostate cancer compounds from differential expressed genes
Prostate cancer (PCa) is a complex and biologically diverse disease with no curative treatment options at present. This study aims to utilize...
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Drug-related emergency department visits: external validation of an assessment tool in a general emergency department population
BackgroundThe process of identifying drug-related hospitalisations is subjective and time-consuming. Assessment tool for identifying hospital...
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Alternate levels versus all levels mini-plate fixation in C3-6 cervical laminoplasty: a retrospective comparative study
ObjectiveThe purpose of this study is to compare radiological and clinical outcomes between alternate levels (C4 and C6) and all levels mini-plate...
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Conservative Management of Occipital Neuralgia Supported by Physical Therapy: A Review of Available Research and Mechanistic Rationale to Guide Treatment
Purpose of ReviewConservative management is consistently recommended as a first line intervention for occipital neuralgia (ON); however, there is...
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The efficacy and safety of combined therapy with endobronchial tamponade and bronchial artery embolization for massive hemoptysis
BackgroundMassive hemoptysis is characterized by its life-threatening nature, potentially leading to airway obstruction and asphyxia. The objective...
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Gender Differences in Perceptions of Psoriatic Arthritis Disease Impact, Management, and Physician Interactions: Results from a Global Patient Survey
IntroductionWe evaluated the impact of gender on disease severity, health-related quality of life (HRQoL), treatment management, and...
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The metabolic consequences of ‘yo-yo’ dieting are markedly influenced by genetic diversity
BackgroundWeight loss can improve the metabolic complications of obesity. However, it is unclear whether insulin resistance persists despite weight...
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The effect of Empagliflozin on echocardiographic parameters in diabetic patients after acute myocardial infarction: A systematic review and meta-analysis with trial sequential analysis
Patients with diabetes mellitus (DM) are at higher risk of cardiovascular events, particularly acute myocardial infarction (MI). Sodium-glucose...
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A case report and literature review: Mycobacterium leprae infection diagnosed by metagenomic next-generation sequencing of cerebrospinal fluid
BackgroundLeprosy is a chronic infectious disease caused by Mycobacterium leprae ( M. leprae ) that is responsible for deformities and irreversible...
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Progressive encephalomyelitis with rigidity and myoclonus: a pediatric case report and literature review
BackgroundProgressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare and life-threatening autoimmune disease of the central nervous...
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Low-dose tenecteplase during cardiopulmonary resuscitation in massive pulmonary embolism
We report the case of an 18-year-old male who presented to the Emergency Department with sudden onset dyspnea. The patient was intubated on arrival,...
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Genetics and sleep bruxism: a systematic review and meta-analysis of studies with twins
ObjectiveTo systematically review the literature regarding the concordance of sleep bruxism (SB) between monozygotic (MZ) and dizygotic (DZ) twins.
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Psychometric properties of the modified Drug Abuse Screening Test Sinhala version (DAST-SL): evaluation of reliability and validity in Sri Lanka
BackgroundPsychoactive drug use is an important public health issue in Sri Lanka as it causes substantial health, social and economic burden to the...
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Timely initiation of complementary feeding and associated factors among mothers having children aged 6 to 24 months in North-West Ethiopia: a comparative cross-sectional study
BackgroundThe timely introduction of complementary foods during infancy is necessary for nutritional reasons, and to enable the transition from milk...