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The ethics of artificial intelligence systems in healthcare and medicine: from a local to a global perspective, and back
Artificial intelligence systems (ai-systems) (e.g. machine learning, generative artificial intelligence), in healthcare and medicine, have been...
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Preliminary field validity of ActiGraph-based energy expenditure estimation in wheelchair users with spinal cord injury
Study designCross-sectional validation study.
ObjectivesTo develop a raw acceleration signal-based random forest (RF) model for predicting total...
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Assessment of airflow limitation in patients with obstructive sleep apnea
BackgroundObstructive sleep apnea (OSA) is a prevalent sleep breathing disorder affecting 9–25% of the general adult population.
AimTo assess...
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Outcomes of Concomitant Cardiac Surgical Procedures Performed During Pediatric Lung Transplantation in the United States
Data on concomitant cardiac surgery (CCS) performed during pediatric lung transplantation (LTx) is limited. Therefore, we conducted a...
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ConKeD: multiview contrastive descriptor learning for keypoint-based retinal image registration
AbstractRetinal image registration is of utmost importance due to its wide applications in medical practice. In this context, we propose ConKeD, a...
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Sperm-Specific CatSper is Not Conserved in All Vertebrates and May Not be the Only Progesterone-Responsive Ion Channel Present in Sperm
Progesterone (P4) acts as a key conserved signalling molecule in vertebrate reproduction. P4 is especially important for mature sperm physiology and...
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Persistent sodium currents in neurons: potential mechanisms and pharmacological blockers
Persistent sodium current (I NaP ) is an important activity-dependent regulator of neuronal excitability. It is involved in a variety of physiological...
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The use of transcutaneous electrical acupoint stimulation to reduce opioid consumption in patients undergoing off-pump CABG: a randomized controlled trial
BackgroundHigh doses of long-acting opioids were used to facilitate off-pump coronary artery bypass grafting procedure, which may result in...
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Prognostic value of laboratory markers in patients with acute pulmonary embolism
BackgroundAcute pulmonary embolism (APE) is a serious illness. Identifying prognostic factors for APE may help in the management of those patients....
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Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h
Aims/hypothesisDisruption of pancreatic islet function and glucose homeostasis can lead to the development of sustained hyperglycaemia, beta cell...
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Trajectories of BMI before and after diagnosis of type 2 diabetes in a real-world population
Aims/hypothesisFew studies have examined the clinical characteristics associated with changes in weight before and after diagnosis of type 2...
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Higher fibre and lower carbohydrate intake are associated with favourable CGM metrics in a cross-sectional cohort of 470 individuals with type 1 diabetes
Aims/hypothesisThe aim of this work was to investigate the association between macronutrient intakes and continuous glucose monitoring (CGM) metrics...
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Multiple ultradian rhythms of metabolism, body temperature and activity in Djungarian hamsters
Djungarian hamsters (Phodopus sungorus) living at constant 15 °C T a in short photoperiod (8:16 h L:D) showed pronounced ultradian rhythms (URs) of...
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Associations of different combinations of moderate-vigorous physical activity and muscle-strengthening activity with mortality among US lung cancer survivors
BackgroundTo investigate the associations of different combinations of moderate to vigorous physical activity (MVPA) and muscle strengthening...
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Technology advances in diabetes pregnancy: right technology, right person, right time
This review outlines some of the extraordinary recent advances in diabetes technology, which are transforming the management of type 1 diabetes...
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Enhanced deep leaning model for detection and grading of lumbar disc herniation from MRI
Lumbar disc herniation is one of the most prevalent orthopedic issues in clinical practice. The lumbar spine is a crucial joint for movement and...
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Early detection of tuberculosis: a systematic review
Tuberculosis remains a significant global health challenge. Tuberculosis affects millions of individuals worldwide. Early detection of tuberculosis...
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CALU promotes lung adenocarcinoma progression by enhancing cell proliferation, migration and invasion
BackgroundLung cancer is the second most common cancer with the highest mortality in the world. Calumenin as a molecular chaperone that not only...
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Temporal and masseter muscle evaluation by MRI provides information on muscle mass and quality in acromegaly patients
PurposeThe impact of GH/IGF-1 levels on skeletal muscle in acromegaly is still controversial. Temporal (TMT) and masseter muscle (MMT) thickness has...