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  1. DNMT3A-R882: a mutation with many paradoxes

    Understanding the underlying mechanism of acute myeloid leukemia (AML) has led to the discovery of novel biomarkers to help predict, treat and...

    Pourya Arbab Jafari, Ramin Bagheri, ... Sajad Goudarzi in Annals of Hematology
    Article 06 July 2024

  2. UBQLN4 promotes the proliferation and invasion of non-small cell lung cancer cell by regulating PI3K/AKT pathway

    Background

    Ubiquilin-4 (UBQLN4), a member of the ubiquilin family, has received limited attention in cancer research to date. Here, we investigated...

    Li He, Heng Chen, ... Rui Zou in Journal of Cancer Research and Clinical Oncology
    Article Open access 06 July 2024

  3. Homoharringtonine may help improve the outcomes of venetoclax and azacitidine in AML1-ETO positive acute myeloid leukemia

    Purpose

    T(8;21)(q22;q22.1)/AML1-ETO positive acute myeloid leukemia (AE-AML) is sensitive to conventional chemotherapy with a favorable prognosis....

    Zhao Yin, Zurong Yao, ... Guopan Yu in Journal of Cancer Research and Clinical Oncology
    Article Open access 06 July 2024

  4. WT1 gene mutations impact post-transplant relapse in myelodysplastic syndrome with excess blasts 2 patients

    Wilms tumor 1 ( WT1 ) gene mutations are infrequent in myelodysplastic syndrome (MDS), but MDS with WT1 mutations (WT1 mut ) is considered high risk for...

    Wenwen Guo, Haixiao Zhang, ... Erlie Jiang in Annals of Hematology
    Article 06 July 2024

  5. Novel Approaches to Managing Patients with Relapsed and Refractory Waldenström Macroglobulinemia

    Purpose of Review

    Waldenström macroglobulinemia is a rare non-Hodgkin lymphoma (NHL) characterized by lymphoplasmacytic bone marrow infiltration...

    Karan L. Chohan, Prashant Kapoor in Current Hematologic Malignancy Reports
    Article 06 July 2024

  6. Risk factors for Non-Hodgkin’s lymphoma in autoimmune disease: a large database analysis

    Immune dysregulation in autoimmune diseases (ADs) is a risk factor for the development of Non-Hodgkin’s lymphoma (NHL). However, the underlying...

    Suma Sri Chennapragada, Shriya Goyal, ... Poornima Ramadas in Annals of Hematology
    Article 05 July 2024

  7. Infectious mononucleosis complicated by transitory Epstein-Barr virus infection of T and natural killer cells

    Epstein-Barr virus (EBV) typically infects B cells in infectious mononucleosis (IM), but a rare case shows EBV infection in T cells. Seven cases of...

    Yanlin Zhang, JianLan **e, ... **aoGe Zhou in Journal of Hematopathology
    Article Open access 05 July 2024

  8. Trypanocidal resistance in two cattle farms using varying diagnostic techniques in southwest Nigeria

    African animal trypanosomosis (AAT) affects the livestock industry, impacting protein intake and herders’ livelihoods. Despite the presence of vector...

    Paul Olalekan Odeniran, Isaiah Oluwafemi Ademola, Johnson Olayide Ade**mi in Comparative Clinical Pathology
    Article 05 July 2024

  9. Oncogenic dependency on SWI/SNF chromatin remodeling factors in T-cell acute lymphoblastic leukemia

    T-cell acute lymphoblastic leukemia (T-ALL) is a hematological malignancy arising from immature thymocytes. Unlike well-known oncogenic transcription...

    Hyoju Kim, Tze King Tan, ... Shi Hao Tan in Leukemia
    Article 05 July 2024

  10. Hematopoietic stem cell transplantation for DLBCL: a report from the European Society for Blood and Marrow Transplantation on more than 40,000 patients over 32 years

    Autologous(auto-) and allogeneic(allo-) hematopoietic stem cell transplantation (HSCT) are key treatments for relapsed/refractory diffuse large...

    Philipp Berning, Mathilde Fekom, ... Norbert Schmitz in Blood Cancer Journal
    Article Open access 05 July 2024

  11. Mast cell density in Merkel cell carcinoma and its correlation with prognostic features and MCPyV status: a pilot study

    Merkel cell carcinoma (MCC) is a rare, highly aggressive, primitive neuroendocrine carcinoma of the skin, the origin of which is not yet fully...

    Gerardo Cazzato, Roberto Tamma, ... Domenico Ribatti in Clinical and Experimental Medicine
    Article Open access 05 July 2024

  12. FRACTION: protocol of a phase II study of Fedratinib and Nivolumab combination in patients with myelofibrosis and resistance or suboptimal response to JAK-inhibitor treatment of the German MPN study group (GSG-MPN)

    Development of Janus-kinase (JAK) inhibitors has revolutionized the therapeutic landscape for patients with myeloproliferative neoplasia (MPN)....

    Susanne Isfort, Nikolas von Bubnoff, ... Florian H. Heidel in Annals of Hematology
    Article Open access 05 July 2024

  13. HIV associated lymphoma: latest updates from 2023 ASH annual meeting

    The incidence, clinical characteristics, and prognostic factors of HIV-associated lymphoma remain poorly defined compared to HIV-negative lymphoma....

    Chaoyu Wang, Qing **ao, ... Yao Liu in Experimental Hematology & Oncology
    Article Open access 05 July 2024

  15. A retrospective observational study of ibrutinib in chronic lymphocytic leukaemia in a real-life setting in France using the national claims database (OSIRIS)

    Background

    Ibrutinib is a Bruton’s tyrosine kinase inhibitor indicated for the first-line treatment and relapse of chronic lymphocytic leukaemia...

    Sylvain Choquet, Clarisse Marchal, ... Vincent Levy in Annals of Hematology
    Article Open access 05 July 2024

  16. Space exploration and cancer: the risks of deeper space adventures

    Ibrahim N. Muhsen, Abba C. Zubair, ... Shahrukh K. Hashmi in Leukemia
    Article 05 July 2024

  17. Gastrointestinal toxicities of proteasome inhibitor therapy

    Purpose

    Proteasome inhibitors (PIs), which cause cell death via tumor suppressor and pro-apoptotic proteins, are integral to treatment of many...

    Jay Shah, Samanthika Devalaraju, ... Yinghong Wang in Journal of Cancer Research and Clinical Oncology
    Article Open access 05 July 2024

  18. A phase-I study of second-line S-IROX for unresectable pancreatic cancer after gemcitabine plus nab-paclitaxel failure

    Gemcitabine plus nab-paclitaxel (GnP) and FOLFIRINOX are widely used as first-line regimens for unresectable pancreatic cancer (PC). When GnP therapy...

    Mitsuru Okuno, Tsuyoshi Mukai, ... Eiichi Tomita in Medical Oncology
    Article 05 July 2024

  19. The effect of erythropoiesis‑stimulating agents on lung cancer patients: a meta‑analysis

    Previous studies have demonstrated that erythropoiesis-stimulating agents (ESAs) can reduce anemia and improve quality of life in cancer patients,...

    Zhenhua Tong, Zhumeng Xu, ... Bin Qi in Clinical and Experimental Medicine
    Article Open access 05 July 2024

  20. Global research states and trends of micro RNA in irritable bowel syndrome: a bibliometric analysis

    Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder, but its diagnosis and treatment remain obscure. Non-coding RNAs...

    Hongxiu Chen, Zhifang Xu, ... Tie Li in Clinical and Experimental Medicine
    Article Open access 05 July 2024
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