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Association between R2CHA2DS2-VASc score and three-vessel coronary artery disease in a large population at high cardiovascular risk
Coronary artery disease (CAD), particularly three-vessel coronary disease (3VD), is the main cause of death in industrialized countries. Chronic...
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Managing abdominal cocoon syndrome complicated by intestinal necrosis and unexpected amelioration of depression after surgery: a case report
BackgroundAbdominal cocoon is a very uncommon yet dangerous cause of intestinal obstruction.
Case presentationWe present a case of a 62-year-old...
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Cervical cystic hygroma in adults: a case report
BackgroundsManifestation of cystic hygroma in adulthood is very rare. The rarity of cystic hygroma in adults has caused problems in its diagnosis and...
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An investigation of inequalities in exposure to PM2.5 air pollution across small areas in Ireland
The link between exposure to air pollution and adverse effects on human health is well documented. Yet, in a European context, research on the...
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The ten-year evaluation of clinical characteristics in congenital lung anomaly in pediatrics; a retrospective study in North of Iran
IntroductionCongenital lung anomalies (CLA) are a group of anomalies, including congenital cystic adenomatoid malformation (CCAM), bronchopulmonary...
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OCTA: Essential or Gimmick?
This commentary article delves into the transformative role of optical coherence tomography angiography (OCTA) in diagnosing and managing a wide...
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Pharmacotherapy as an Augmentation to Bariatric Surgery for Obesity
A global obesity pandemic is one of the most significant health threats worldwide owing to its close association with numerous comorbidities such as...
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Management of patient with Fusobacterim nucletum related pleural empyema: intrapleural antibiotic therapy can be considered for salvage therapy
Pleural empyema can lead to significant morbidity and mortality despite chest drainage and antibiotic treatment, necessitating novel and minimally...
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Homoharringtonine may help improve the outcomes of venetoclax and azacitidine in AML1-ETO positive acute myeloid leukemia
PurposeT(8;21)(q22;q22.1)/AML1-ETO positive acute myeloid leukemia (AE-AML) is sensitive to conventional chemotherapy with a favorable prognosis....
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UBQLN4 promotes the proliferation and invasion of non-small cell lung cancer cell by regulating PI3K/AKT pathway
BackgroundUbiquilin-4 (UBQLN4), a member of the ubiquilin family, has received limited attention in cancer research to date. Here, we investigated...
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Impact of non-emergency surgical timing on postoperative recovery quality in mild or asymptomatic SARS-CoV-2 infected patients: a grouped cohort study
ObjectiveTo explore the relationship between the timing of non-emergency surgery in mild or asymptomatic SARS-CoV-2 (severe acute respiratory...
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Effects of concurrent aerobic and strength training in women diagnosed with non-metastatic breast cancer: a systematic review and meta-analysis
PurposeTo investigate the potential impact of concurrent aerobic and strength training (CT) on women diagnosed with breast cancer.
Methods ...
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Prevalence of stunting and its correlates among children under 5 in Afghanistan: the potential impact of basic and full vaccination
BackgroundChild stunting is prevalent in low and middle-income countries (LMICs), but an information gap remains regarding its current prevalence,...
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Analyzing the correlation between low proportion of hobnail features in papillary thyroid carcinoma and clinical aggressiveness risk
PurposeHobnail features may enhance the clinical aggressiveness of papillary thyroid carcinoma (PTC). However, whether a low proportion (<30%) of...
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Comparison of remimazolam tosilate and propofol during induction and maintenance of general anesthesia in patients undergoing laparoscopic cholecystectomy: a prospective, single center, randomized controlled trial
BackgroundRemimazolam tosilate (RT) is a new, ultrashort-acting benzodiazepine. Here, we investigated the efficacy and safety of RT for general...
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Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h
Aims/hypothesisDisruption of pancreatic islet function and glucose homeostasis can lead to the development of sustained hyperglycaemia, beta cell...
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Trajectories of BMI before and after diagnosis of type 2 diabetes in a real-world population
Aims/hypothesisFew studies have examined the clinical characteristics associated with changes in weight before and after diagnosis of type 2...
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Participants’ perspectives of being recruited into a randomised trial of a weight loss intervention before colorectal cancer surgery: a qualitative interview study
BackgroundThe period between cancer diagnosis and surgery presents an opportunity for trials to assess the feasibility of behaviour change...
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Causal relationship between bone mineral density and intervertebral disc degeneration: a univariate and multivariable mendelian randomization study
BackgroundAlthough previous studies have suggested a possible association between bone mineral density (BMD) and intervertebral disc degeneration...
