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Emerging biologic augmentation strategies for meniscal repair: a systematic review
BackgroundMeniscal repair should be the gold standard. However, the meniscus is poorly vascularized and even an excellent meniscus repair may not...
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Young People’s Barriers and Facilitators of Engagement with Web-Based Mental Health Interventions for Anxiety and Depression: A Qualitative Study
BackgroundThe prevalence of anxiety and depressive symptoms in young people have increased in many countries around the world. Web-based mental...
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Scale and rate heterogeneity in the EQ-5D-5L valuation
ObjectivesTo estimate values on a quality-adjusted life year (QALY) scale using individual preference evidence, choice analyses typically include...
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Effectiveness of synthetic versus autologous bone grafts in foot and ankle surgery: a systematic review and meta-analysis
BackgroundAll orthopaedic procedures, comprising foot and ankle surgeries, seemed to show a positive trend, recently. Bone grafts are commonly...
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Diffusion-tensor magnetic resonance imaging as a non-invasive assessment of extracellular matrix remodeling in lumbar paravertebral muscles of rats with sarcopenia
BackgroundExtracellular matrix (ECM) remodeling in skeletal muscle is a significant factor in the development of sarcopenia. This study aims to...
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Evaluating a National Academic Mentorship Program to Grow the Next Generation of Gender-based Violence Intervention and Prevention (VIP) Researchers
PurposeThe personal, economic, and societal costs and consequences of gender-based violence are significant. Although much violence intervention and...
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Stable Response and Sustained Improvement of Itch and Sleep Symptoms in Patients with Atopic Dermatitis Treated with Lebrikizumab over 52 Weeks
BackgroundLebrikizumab demonstrated significant improvement versus placebo for measures of skin clearance and patient-reported outcomes at weeks 16...
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A Cross-lagged Longitudinal Study of Bidirectional Associations between Meaning in Life and Academic Engagement: The Mediation of Hope
Previous research has established a positive correlation between meaning in life and academic achievement, yet several gaps remain unaddressed....
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Replacement of sedentary behavior with various physical activities and the risk of incident depression: a prospective analysis of accelerator-measured and self-reported UK Biobank data
PurposeTo examine the dose‒response relationships of sedentary behavior (SB) and physical activities (PAs) with depression, and to explore the...
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Impact of the COVID-19 pandemic on antidepressant consumption in the Central region of Portugal: interrupted time series
PurposeTo evaluate the impact of the pandemic on the consumption of antidepressive agents in Central Portugal.
MethodsTo estimate the causal effect...
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Predictors of High Healthcare Cost Among Patients with Generalized Myasthenia Gravis: A Combined Machine Learning and Regression Approach from a US Payer Perspective
BackgroundHigh healthcare costs could arise from unmet needs. This study used random forest (RF) and regression methods to identify predictors of...
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Nexus Between Financial Inclusion, Digital Inclusion and Health Outcomes: Evidence from Develo** Economies
This research analyses the nexus between financial inclusion, digital inclusion and health outcomes in develo** countries. In comparison with...
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“So Just with every Facet, Every Side of this Journey, They Have Somebody Walking alongside with Them”: Practitioners’ Perspectives of the Lethality Assessment Program as a Collaborative Model
PurposeAscriticism of the criminalization of domestic violence (DV) has gained momentum, programs such as the Lethality Assessment Program (LAP)...
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Consensus-building to improve implementation of NICE guidance on planning for end-of-life treatment and care: a mixed-methods study
BackgroundDespite the availability of guidance for the provision of good end-of-life care, there are significant variations across the UK in its...
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Association between negative life events and suicidal behavior in adolescents: roles of core self-evaluation, depression and gender
PurposeNegative life events are essential proximal factors that may induce suicidal behavior in adolescents, but the mechanisms connecting this link...
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Specialized expertise among healthcare professionals in palliative care - A sco** review
BackgroundThe generalist-plus-specialist palliative care model is endorsed worldwide. In the Netherlands, the competencies and profile of the...
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“Some Handle It in Ways Others See as Insane:” College Individuals’ Meaning-Making about their Motivations for Severe Unwanted Pursuit Behaviors
PurposePost-relationship pursuit can range from normative to problematic, including stalking. While there are some theories and research about...
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The association between malnutrition risk and revised Edmonton Symptom Assessment System (ESAS-r) scores in an adult outpatient oncology population: a cross-sectional study
BackgroundCancer-associated malnutrition is associated with worse symptom severity, functional status, quality of life, and overall survival....
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Changes in femoral anteversion after intramedullary nailing for pediatric femoral shaft fracture: a multicenter study
BackgroundThe rotational change after using a flexible intramedullary (IM) nail for femoral shaft fractures has been a concern for many surgeons....