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Exosomes derived from human urine–derived stem cells ameliorate IL-1β-induced intervertebral disk degeneration
BackgroundHuman intervertebral disk degeneration (IVDD) is a sophisticated degenerative pathological process. A key cause of IVDD progression is...
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Preliminarily exploring the intraoperative ultrasonography characteristics of patients with degenerative cervical myelopathy
BackgroundHow to quickly read and interpret intraoperative ultrasound (IOUS) images of patients with degenerative cervical myelopathy (DCM) to obtain...
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Combined neurokinin-1 receptor antagonist and sorafenib is a promising approach for hepatocellular carcinoma therapy
BackgroundHCC (Hepatocellular carcinoma) is the most common primary malignant cancer in the liver. Treatment options to incurable HCC such as...
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Non-emergency department (ED) interventions to reduce ED utilization: a sco** review
BackgroundEmergency department (ED) crowding is a global burden. Interventions to reduce ED utilization have been widely discussed in the literature,...
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Nomogram for predicting the probability of rectal anastomotic re-leakage after stoma closure: a retrospective study
BackgroundIn this study, we aimed to identify the risk factors in patients with rectal anastomotic re-leakage and develop a prediction model to...
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Sleep profiles of different psychiatric traits
Disturbed sleep comes in many forms. While the key role of sleep in mental health is undisputed, our understanding of the type of slee** problems...
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Introduction and impact of routine whole genome sequencing in the diagnosis and management of sarcoma
BackgroundSarcomas are diverse neoplasms with highly variable histological appearances in which diagnosis is often challenging and management options...
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Temporal relationship between hepatic steatosis and fasting blood glucose elevation: a longitudinal analysis from China and UK
BackgroundThe link between nonalcoholic fatty liver disease and type 2 diabetes has not been fully established. We investigated the temporal...
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Comparison of FGM prevalence among Nigerian women aged 15–49 years using two household surveys conducted before and after the COVID-19 pandemic
BackgroundDue to its economic burden and change of focus, there is no gainsaying of the potential impacts of the COVID-19 pandemic on the progress of...
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Advancements in differentiation between sperm cells and epithelial cells for efficient forensic DNA analysis in sexual assault cases
Most of the sexual assault casework samples are of mixed sources. Forensic DNA laboratories are always in the requirement of a precise technique for...
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Bezold’s abscess, an uncommon complication of otitis media and cholesteatoma: a case report
BackgroundMastoiditis frequently occurs in children as they are more susceptible to middle ear infections, but infrequently occurs in adults. A rare...
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Presence of Fusobacterium nucleatum in relation to patient survival and an acidic environment in oesophagogastric junction and gastric cancers
BackgroundFusobacterium nucleatum inhabits the oral cavity and affects the progression of gastrointestinal cancer. Our prior findings link F....
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Initial surgery for spontaneous intestinal perforation in extremely low birth weight infants is not associated with mortality or in-hospital morbidities
ObjectiveDetermine short-term outcomes following peritoneal drain (PD), laparotomy (LAP) after PD (PD-LAP), and LAP in extremely low birth weight...
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Postoperative EEG abnormalities in relation to neurodevelopmental outcomes after pediatric cardiac surgery
BackgroundWe had reported that postoperative EEG background including sleep-wake cycle (SWC) and discharge (seizures, spikes/sharp waves)...
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Prevalence of diabetes among Indigenous women in Guatemala: a retrospective chart review
ObjectiveThe objective of this study is to investigate the prevalence of diabetes in a clinical population of primarily Indigenous women in Guatemala.
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Blood pressure is associated with knee pain severity in middle-aged and elderly individuals with or at risks for osteoarthritis: data from the Osteoarthritis Initiative
BackgroundHypertension is a common comorbidity of osteoarthritis (OA). Joint pain is the main clinical manifestation of OA. Knowledge about the...
