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Environmental Oxidative Stress – Environmental Sources of ROS
Environmental factors are known sources for oxidative stress. In consequence of the numerous influences that define our environment, environmental...
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Endogenous Oxidant-Generating Systems
Although organisms respiring air oxygen use their energy sources in an optimal way they are threatened by the compulsory formation of reactive oxygen...
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Low Molecular Weight Antioxidants
Low molecular weight antioxidants are an important part of the antioxidative defense mechanisms of cells and organisms. This chapter gives a short...
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Modulation of Cellular Signaling Processes by Reactive Oxygen Species
Exposure of cells to reactive oxygen species (ROS) may result not only in cell death by excessive oxidation of biomolecules but also cause the...
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Glutathione
Glutathione is the most abundant non-protein thiol in cells. It is a tripeptide with two important structural features: the thiol group and the...
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The Broad Spectrum of Responses to Oxidative Stress in Proliferating Cells
Proliferating mammalian cells exhibit a broad spectrum of responses to oxidative stress, depending on the stress level encountered. Very low levels...
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The Tail of Two Rivers in Tasmania: The Derwent and Huon Estuaries
The Derwent and Huon Rivers are two relatively small river systems in the southeast of Tasmania (Australia). They terminate in estuaries that are...
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The Sacca di Goro Lagoon and an Arm of the Po River
The Po di Volano canal–Sacca di Goro lagoon is a small hydrographic system partially located in the southern part of the Po River Delta. The total...
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Pesticides in the Great Lakes
Pesticides have been widely and heavily used in agriculture in the Great Lakes Basin (approximately 93000 tons were used in 1995 alone). Herbicides...
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Geochemistry of the Amazon Estuary
The Amazon River supplies more freshwater to the ocean than any other river in the world. This enormous volume of freshwater forces the estuarine...
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Brominated Flame Retardants in the Great Lakes
Brominated flame retardants in the Great Lakes have not been as well studied as many of the polychlorinated pollutants, especially PCBs, but in the...
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Role of Particle Sorption Properties in the Behavior and Speciation of Trace Metals in Macrotidal Estuaries: The Cadmium Example
The role of particles in the fate and speciation of trace metals in macrotidal estuaries was studied using a surface complexation model (MOCO)....
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Polychlorinated Biphenyls in the Great Lakes
This chapter reviews the scientific understanding of the concentrations, trends, and cycling of polychlorinated biphenyls (PCBs) in the Great...
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Polycyclic Aromatic Hydrocarbons in the Great Lakes
Polycyclic aromatic hydrocarbons (PAHs) are produced during the incomplete combustion of organic material. They can also be produced through...
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The São Francisco Estuary, Brazil
This is a first account of the physical and biogeochemical characteristics of the tropical São Francisco (SF) estuarine system, East Brazil,...
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Persistent Organic Pollutants in the Great Lakes: An Overview
This chapter presents background information on the Great Lakes and summarizes the content of each chapter of this book.
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Chemical Modifications of Biomolecules by Oxidants
There is strong evidence in support of the oxidation of biomolecules during normal physiology and under conditions of environmental or pathological...
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DNA Repair: Mechanisms and Measurements
The early findings that significant amounts of modifications are induced to the cellular DNA both spontaneously and as a consequence of metabolism...
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Mitochondrial Free Radical Production, Antioxidant Defenses and Cell Signaling
Mitochondria were classically recognized as the organelles that produce the energy required to drive the endergonic processes of cell life, but now...
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Protein Repair and Degradation
Protein oxidation is one of the important processes taking place during oxidative stress. Numerous amino acids can be modified within proteins...