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Insomnia During Late Life: Potential Pathways Toward Suicide Risk
Purpose of ReviewAs the global population continues to age, the identification of drivers of suicide risk in older adults is of increasing...
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Managing Micronutrient Deficiencies in High-Risk Patients: No Small Feat!
Abstract Purpose of ReviewMicronutrients are vital dietary components for growth and development. Adequate intake of vitamins and minerals through...
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Prolonged water-only fasting in the management of low-grade follicular lymphoma: a case series
BackgroundFollicular lymphoma typically follows an indolent and relapsing course often requiring several treatment cycles to achieve remission. Some...
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Immune checkpoint inhibitors-induced diabetes mellitus (review)
Immune checkpoint inhibitors (ICIs) have become extensively utilized in the early-stage treatment of various cancers, offering additional therapeutic...
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Assessing the efficacy of topical formulations in diabetic neuropathy: a narrative review
BackgroundWe conducted a review of topical medications available for alleviation of diabetic neuropathic pain (DNP) and compared their efficacy with...
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The Role of Physical Exercise as a Therapeutic Tool to Improve Lipedema: A Consensus Statement from the Italian Society of Motor and Sports Sciences (Società Italiana di Scienze Motorie e Sportive, SISMeS) and the Italian Society of Phlebology (Società Italiana di Flebologia, SIF)
Purpose of ReviewThis consensus statement from the Italian Society of Motor and Sports Sciences ( Società Italiana di Scienze Motorie e Sportive ,...
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Neuropsychological complications of hypoprolactinemia
Prolactin (PRL) is primarily produced by the pituitary lactotrophic cells and while initially named for its role in lactation, PRL has several other...
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Inappropriate treatment of pulmonary aspergillosis caused by Aspergillus flavus in susceptible pediatric patients: a case series
BackgroundPulmonary aspergillosis is a prevalent opportunistic fungal infection that can lead to mortality in pediatric patients with underlying...
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Environmental factors affecting female fertility
IntroductionOver the recent years, scientific community has increased its interest on solving problems of female fertility pathology. Many factors...
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Impact of USMLE Step 1 transition to pass/fail scoring system on medical students’ anxiety, sleep quality, and burnout
IntroductionOriginally designed to evaluate the application of foundational scientific knowledge in clinical contexts, the United States Medical...
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Filling the “GAP” in Real-World Assessment of Psoriatic Arthritis Disease Activity: Performance Characteristics of a Global/Pain Composite Endpoint
IntroductionSome retrospective data sources, such as electronic health records in the USA, report composite outcome measures not fully validated in...
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Post-tuberculosis treatment paradoxical reactions
Paradoxical reactions (PR) to tuberculosis (TB) treatment are common during treatment, but have also been described after treatment. A presentation...
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Mesenchymal stem cells ameliorate inflammation and pyroptosis in diabetic cardiomyopathy via the miRNA-223-3p/NLRP3 pathway
BackgroundDiabetic cardiomyopathy (DCM) stands as the primary cause of heart failure and mortality among patients with diabetes. Nevertheless,...
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THRIVE, ASTRAL, and iScore scales for predicting prognosis of mechanical thrombectomy in patients with acute ischemic stroke
ObjectiveTo validate the predictive performance of the THRIVE, ASTRAL, and iScore scales for clinical functional outcomes following mechanical...
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Impact of multidrug resistance on the virulence and fitness of Pseudomonas aeruginosa: a microbiological and clinical perspective
Pseudomonas aeruginosa is one of the most common nosocomial pathogens and part of the top emergent species associated with antimicrobial resistance...
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The importance of sleep for the develo** brain
Purpose of reviewThis paper summarizes recent research regarding the possible contribution of sleep to brain development. Major milestones in brain...
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Cai’s herbal tea enhances mitochondrial autophagy of type 1 diabetic mellitus β cells through the AMPK/mTOR pathway and alleviates inflammatory response
BackgroundThis study investigates the therapeutic mechanisms of Cai’s Herbal Tea in Type 1 Diabetes Mellitus (T1DM) mice, focusing on its effects on...
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Sex differences in the association between vitamin D and prediabetes in adults: A cross-sectional study
Background/ObjectivesVitamin D status has been shown to be associated with prediabetes risk. However, epidemiologic evidence on whether sex modulates...