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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive...
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Oncological features of sporadic vs. hereditary pediatric medullary thyroid cancer
PurposeNo genomic data have been put forth that prove beyond a shadow of doubt that sporadic medullary thyroid cancer (MTC) occurs in infancy,...
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Thyroid complications after hemopoietic stem cell transplantation in children and adolescents
PurposeTo evaluate the prevalence of thyroid dysfunction and its association with possible contributing factors related to diagnosis and treatment in...
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Clinicopathological spectrum, management, and outcome of ectopic parathyroid carcinoma: Experience with 24 cases
PurposeEctopic parathyroid carcinoma (EPC) is a rare clinical entity with multiple diagnostic pitfalls, making surgical cures challenging. We...
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Imaging-based body fat distribution and diabetic retinopathy in general US population with diabetes: an NHANES analysis (2003–2006 and 2011–2018)
BackgroundLimited studies have investigated the correlation between fat distribution and the risk of diabetic retinopathy (DR) in the general...
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Inhibitors of apolipoprotein C3, triglyceride levels, and risk of pancreatitis: a systematic review and meta-analysis
In recent years, novel apoC3 inhibitor therapies for the treatment of hypertriglyceridemia have been developed and assessed through phase II and III...
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DNA Methylation-derived biological age and long-term mortality risk in subjects with type 2 diabetes
BackgroundIndividuals with type 2 diabetes (T2D) face an increased mortality risk, not fully captured by canonical risk factors. Biological age...
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Breathing difficulties in a nonagenarian: a self report
This is a self report. It is age related because I am 96 years old; about 5 years ago I was asymptomatic in this respect. I describe the difficulties...
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Sex differences in membrane properties and cellular excitability of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of pre- and mid-adolescent mice
BackgroundThe transition from childhood to adulthood, or adolescence, a developmental stage, is characterized by psychosocial and biological changes....
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Non-osteoporotic fractures are associated with increased risk of subsequent major osteoporotic fractures
SummaryWe studied the association between non-osteoporotic fractures and future major osteoporotic fractures, using UK health records....
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Healthcare costs and medical utilization patterns associated with painful and severe painful diabetic peripheral neuropathy
PurposePainful diabetic peripheral neuropathy (DPN) is a common complication in patients with diabetes. It is associated with a poor quality of life...
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Comprehensive analysis of the association between triglyceride-glucose index and coronary artery disease severity across different glucose metabolism states: a large-scale cross-sectional study from an Asian cohort
BackgroundThe triglyceride-glucose (TyG) index is associated with the development and prognosis of coronary artery disease (CAD). However, the impact...
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Improvement of early miscarriage rates in women with adenomyosis via oxytocin receptor antagonist during frozen embryo transfer-a propensity score-matched study
BackgroundDysfunctional uterine peristalsis seems to play a pivotal role in hindering embryo implantation among women diagnosed with adenomyosis....
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Safety of embryo cryopreservation: insights from mid-term placental transcriptional changes
BackgroundIn recent years, with benefits from the continuous improvement of clinical technology and the advantage of fertility preservation, the...
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Protective defunctioning stoma in bowel segmental resection at the time of total hysterectomy for endometriosis: when less is more
PurposeTo compare postoperative complications in women undergoing total hysterectomy with segmental resection (TH-SR) for intestinal endometriosis...
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Influence of prediabetes on the prognosis of patients with myocardial infarction: a meta-analysis
BackgroundPrevious studies evaluating the association between prediabetes the prognosis of patients with acute myocardial infarction (AMI) showed...
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Does metformin really reduce prostate cancer risk: an up-to-date comprehensive genome-wide analysis
BackgroundThe relationship between metformin use and prostate cancer (PCa) risk has yet to be clear despite more than a decade of debate on this...
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A DPC Database Study on the Safety of Atezolizumab/Carboplatin/Etoposide in Extensive-Disease Small Cell Lung Cancer in Japanese Patients
IntroductionAtezolizumab, carboplatin, and etoposide (ACE) therapy is a standard of care for extensive-disease small cell lung cancer (SCLC);...
