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PxBLAT: an efficient python binding library for BLAT
BackgroundWith the surge in genomic data driven by advancements in sequencing technologies, the demand for efficient bioinformatics tools for...
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Leveraging permutation testing to assess confidence in positive-unlabeled learning applied to high-dimensional biological datasets
BackgroundCompared to traditional supervised machine learning approaches employing fully labeled samples, positive-unlabeled (PU) learning techniques...
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Increased [18F]FDG uptake of radiation-induced giant cells: a single-cell study in lung cancer models
Positron emission tomography (PET), a cornerstone in cancer diagnosis and treatment monitoring, relies on the enhanced uptake of fluorodeoxyglucose ([
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Empowering standardization of cancer vaccines through ontology: enhanced modeling and data analysis
BackgroundThe exploration of cancer vaccines has yielded a multitude of studies, resulting in a diverse collection of information. The heterogeneity...
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iGenSig-Rx: an integral genomic signature based white-box tool for modeling cancer therapeutic responses using multi-omics data
Multi-omics sequencing is poised to revolutionize clinical care in the coming decade. However, there is a lack of effective and interpretable...
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Phantoms for Quantitative Body MRI: a review and discussion of the phantom value
In this paper, we review the value of phantoms for body MRI in the context of their uses for quantitative MRI methods research, clinical trials, and...
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Diffusion of curcumin in PLGA-based carriers for drug delivery: a molecular dynamics study
Context:The rapid growth and diversification of drug delivery systems have been significantly supported by advancements in micro- and...
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The Malaria Box molecules: a source for targeting the RBD and NTD cryptic pocket of the spike glycoprotein in SARS-CoV-2
ContextSARS-CoV-2, responsible for COVID-19, has led to over 500 million infections and more than 6 million deaths globally. There have been limited...
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EPI-Trans: an effective transformer-based deep learning model for enhancer promoter interaction prediction
BackgroundRecognition of enhancer–promoter Interactions (EPIs) is crucial for human development. EPIs in the genome play a key role in regulating...
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Extraction of uranyl from spent nuclear fuel wastewater via complexation—a local vibrational mode study
ContextThe efficient extraction of uranyl from spent nuclear fuel wastewater for subsequent reprocessing and reuse is an essential effort toward...
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Using GPT-4 to write a scientific review article: a pilot evaluation study
GPT-4, as the most advanced version of OpenAI’s large language models, has attracted widespread attention, rapidly becoming an indispensable AI tool...
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Coherent spin transport in a copper protein
ContextThe coherent electron/spin transport in azurin, a species of copper protein, was calculated based on the Landauer model. The research is...
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SATIN: a micro and mini satellite mining tool of total genome and coding regions with analysis of perfect repeats polymorphism in coding regions
BackgroundTandem repeats are specific sequences in genomic DNA repeated in tandem that are present in all organisms. Among the subcategories of TRs...
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Minimization of occurrence of retained surgical items using machine learning and deep learning techniques: a review
Retained surgical items (RSIs) pose significant risks to patients and healthcare professionals, prompting extensive efforts to reduce their...
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Modeling Career Paths in Biomedical Quality Engineering
Biomedical Quality Engineers (QEs) ensure that medical devices are safe, reliable, and consistent. To better understand career pathways for...
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Tunable electronic and magnetic properties of defective g-ZnO monolayer do** with non-metallic elements
ContextThe electronic and magnetic properties of non-metallic (NM) elements do** defective graphene-like ZnO (g-ZnO) monolayer including O vacancy...
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Temperature and humidity effects on the acetone gas sensing of pristine and Pd-doped WO3 clusters: A transition state theory study
ContextThe performance of pristine and Pd-doped WO 3 acetone gas sensors is calculated theoretically and compared with available experimental...
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“Interdisciplinary Education,” “R&D,” and “Contamination”: Comparing the Stressors of Biomedical Engineering Doctoral Students to Other Engineering Fields
Doctoral students experience high rates of mental health distress and dropout; however, the mental health and wellness of engineering doctoral...
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Simulations on coal water slurry gasification by molecular dynamics method with ReaxFF
ContextCoal water slurry (CWS) is a new type of liquid coal product with low pollution, which is mainly used in the chemical industry to produce...
