Search
Search Results
-
The Broad Spectrum of Responses to Oxidative Stress in Proliferating Cells
Proliferating mammalian cells exhibit a broad spectrum of responses to oxidative stress, depending on the stress level encountered. Very low levels...
-
Low Molecular Weight Antioxidants
Low molecular weight antioxidants are an important part of the antioxidative defense mechanisms of cells and organisms. This chapter gives a short...
-
Environmental Oxidative Stress – Environmental Sources of ROS
Environmental factors are known sources for oxidative stress. In consequence of the numerous influences that define our environment, environmental...
-
Endogenous Oxidant-Generating Systems
Although organisms respiring air oxygen use their energy sources in an optimal way they are threatened by the compulsory formation of reactive oxygen...
-
Glutathione
Glutathione is the most abundant non-protein thiol in cells. It is a tripeptide with two important structural features: the thiol group and the...
-
Modulation of Cellular Signaling Processes by Reactive Oxygen Species
Exposure of cells to reactive oxygen species (ROS) may result not only in cell death by excessive oxidation of biomolecules but also cause the...
-
Chemical Modifications of Biomolecules by Oxidants
There is strong evidence in support of the oxidation of biomolecules during normal physiology and under conditions of environmental or pathological...
-
DNA Repair: Mechanisms and Measurements
The early findings that significant amounts of modifications are induced to the cellular DNA both spontaneously and as a consequence of metabolism...
-
Mitochondrial Free Radical Production, Antioxidant Defenses and Cell Signaling
Mitochondria were classically recognized as the organelles that produce the energy required to drive the endergonic processes of cell life, but now...
-
Protein Repair and Degradation
Protein oxidation is one of the important processes taking place during oxidative stress. Numerous amino acids can be modified within proteins...
-
Superoxide Dismutases and Catalase
Superoxide dismutases (SODs) and catalase represent the primary enzymatic defense against reactive oxygen species. Both enzymes are present in...
-
Evolution of Titanium Interbody Cages and Current Uses of 3D Printed Titanium in Spine Fusion Surgery
Purpose of ReviewTo summarize the history of titanium implants in spine fusion surgery and its evolution over time.
Recent FindingsTitanium...
-
Infertility as Trauma: Understanding the Lived Experience of Involuntary Childlessness
Infertility, to those who are affected by it, is much more than whether one manages (or not) to have a child: it can be a traumatizing experience....
-
Emerging biologic augmentation strategies for meniscal repair: a systematic review
BackgroundMeniscal repair should be the gold standard. However, the meniscus is poorly vascularized and even an excellent meniscus repair may not...
-
Imagining the Postcolonial in Central Eastern Europe: Controversies of the Czech Manifesto for Decolonization
In September 2020, the Czech digital audience was confronted with a request to critically revise local history and the current official cultural and...
-
Diffusion-tensor magnetic resonance imaging as a non-invasive assessment of extracellular matrix remodeling in lumbar paravertebral muscles of rats with sarcopenia
BackgroundExtracellular matrix (ECM) remodeling in skeletal muscle is a significant factor in the development of sarcopenia. This study aims to...
-
Effectiveness of synthetic versus autologous bone grafts in foot and ankle surgery: a systematic review and meta-analysis
BackgroundAll orthopaedic procedures, comprising foot and ankle surgeries, seemed to show a positive trend, recently. Bone grafts are commonly...
-
Religious Belief Among Women in Australia: Characteristics and Role in Influencing Children’s Health-Related Quality of Life and Lifestyle
Religiosity can be an important factor in women’s health-related behaviour, attitudes, and decision-making. Evidence however, regarding the...
-
Safety evaluation of outpatient vs inpatient unicompartmental knee arthroplasty: a systematic review and meta-analysis
PurposeThis systematic review and meta-analysis aimed to evaluate the safety of outpatient and inpatient Unicompartmental Knee Arthroplasty (UKA)...
-
Evaluating a National Academic Mentorship Program to Grow the Next Generation of Gender-based Violence Intervention and Prevention (VIP) Researchers
PurposeThe personal, economic, and societal costs and consequences of gender-based violence are significant. Although much violence intervention and...
