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Polymer Therapeutics for Cancer: Current Status and Future Challenges
Drug delivery systems for cancer therapeutics have revolutionized medicine. Delivery systems have improved the efficacy and reduced the toxicity of...
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Nanostructured Devices Based on Block Copolymer Assemblies for Drug Delivery: Designing Structures for Enhanced Drug Function
Block copolymers spontaneously assemble into nanoscaled polymeric micelles, which have significant potential as drug carriers. Following much work...
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Dumbbell Model for Dilute and Semi-Dilute Solutions
Dumbbell models are very crude representations of polymer molecules. Too crude to be of much interest to a polymer chemist, since it in no way...
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Equilibrium Statistics: Monte Carlo Methods
Monte Carlo methods use random numbers, or ‘random’ sequences, to sample from a known shape of a distribution, or to extract distribution by other...
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Effects of Multi-Scale Heterogeneity
It is generally agreed that problems with multi-scale heterogeneity present the biggest challenge to computation and understanding. A few such...
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4 Compositional Modelling of Distributed-Parameter Systems
The Hamiltonian formulation of distributed-parameter systems has been a challenging reserach area for quite some time. (A nice introduction,...
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Applications of the Correlation Length
The correlation length is the system–dependent parameter, which defines the structure of the dominant current–carrying (electric or fluid) paths....
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Pressure Saturation Curves and the Critical Volume Fraction for Percolation
The pressure-saturation curves of porous media give fundamental information about the pore space. In equilibrium, ignoring effects due to hysteresis,...
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A On the Literature’s Two Different Definitions of Uniform Global Asymptotic Stability for Nonlinear Systems
In this appendix we discuss two different deffnitions of uniform global asymptotic stability (UGAS), both used in the literature. In the first one,...
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2 Observer Design for Nonlinear Systems
In this chapter, an overview of main observability problems and possible observer designs for nonlinear systems is proposed. In particular the...
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3 Sampled-data Control of Nonlinear Systems
This chapter provides some of the main ideas resulting from recent developments in sampled-data control of nonlinear systems. We have tried to bring...
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7 Structural Properties of Linear Systems – Part II: Structure at Infinit
This chapter is the sequel of [7]. Its topic is the structure at infinity of discrete and continuous linear time-varying systems in a unified...
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Molecular-Scale Studies on Biopolymers Using Atomic Force Microscopy
The atomic force microscope (AFM) is capable of acquiring a range of structural and physicochemical information on a wide range of biopolymers. The...
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Polymer Genomics
Biological activities of biocompatible synthetic polymers used in drug delivery, gene delivery, vaccine development or biomaterial surface...
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Polymeric Systems for Bioinspired Delivery of Angiogenic Molecules
Growth factors are increasingly utilized to promote regeneration of lost or compromised tissues and organs. However, current strategies applying...
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Biopolyesters in Tissue Engineering Applications
Tissue engineering is a rapidly growing interdisciplinary field of research focused on the development of vital autologous tissue through the use...
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Interfaces to Control Cell-Biomaterial Adhesive Interactions
Cell adhesion to adsorbed proteins and adhesive sequences engineered on surfaces is crucial to cellular and host responses to implanted devices,...
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Chain Model for Dilute Solutions
Various experimental observations reveal an important aspect of the behavior of polymer solutions which is not captured by FENE dumbbell models. When...
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Irreducible and Isotropic Cartesian Tensors
In this chapter we summarize definitions and properties of cartesian, anisotropic, irreducible and isotropic tensors and related tensor operators. In...