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Peptides for microbe-induced cancers: latest therapeutic strategies and their advanced technologies
Cancer is a significant global health concern associated with multiple distinct factors, including microbial and viral infections. Numerous studies...
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A dual-targeting approach with anti-IL10R CAR-T cells engineered to release anti-CD33 bispecific antibody in enhancing killing effect on acute myeloid leukemia cells
BackgroundImmunotherapies, including chimeric antigen receptor (CAR) T cells and bispecific antibodies (BsAbs), encounter several challenges in the...
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CircRNA and lncRNA-associated competing endogenous RNA networks in medulloblastoma: a sco** review
BackgroundMedulloblastoma is one of the common primary central nervous system (CNS) malignancies in pediatric patients. The main treatment is...
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Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the “Smart” exosome nanoparticle therapy
BackgroundDiffuse large B-cell lymphoma (DLBCL) represents a prevalent malignant tumor, with approximately 40% of patients encountering treatment...
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What does “urgency” mean when prioritizing cancer treatment? Results from a qualitative study with German oncologists and other experts during the COVID-19 pandemic
PurposeCancer care in Germany during the COVID-19 pandemic was affected by resource scarcity and the necessity to prioritize medical measures. This...
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Resveratrol-based nano-formulations as an emerging therapeutic strategy for ovarian carcinoma: autophagy stimulation and SIRT-1/Beclin/MMP-9/P53/AKT signaling
BackgroundResveratrol (RVS) is a stilbene derivative polyphenolic compound extensively recognized for its anti-inflammatory, antioxidant and...
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Consumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial
Consumer-grade wearable technology has the potential to support clinical research and patient management. Here, we report results from the RATE-AF...
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Efficacy of chemotherapy plus immune checkpoint inhibitors in patients with non-small cell lung cancer who have rare oncogenic driver mutations: a retrospective analysis
BackgroundTargeted therapy is now the standard of care in driver–oncogene-positive non-small cell lung cancer (NSCLC). Its initial clinical effects...
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Epithelial to Mesenchymal Transition in Neuroblastoma: Mechanisms and Therapeutic Considerations
Purpose of ReviewNeuroblastoma (NB) is a solid tumour of the extracranial region in children, and it originates from the develo** sympathetic...
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Ferroptosis crosstalk in anti-tumor immunotherapy: molecular mechanisms, tumor microenvironment, application prospects
Immunotherapies for cancer, specifically immune checkpoint inhibition (ICI), have shown potential in reactivating the body’s immune response against...
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Food security among black breast cancer survivors in Maryland: insights from an online pilot study
PurposeFood security, and reliable access to nutritious food, is essential for maintaining health yet remains elusive for many, including U.S....