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Analysis of the Rate and Reasons for Discard Blood and Its Components from 2019 to 2022 in a Single Blood Service in China
IntroductionThe discard rate of blood services as a crucial quality metric for monitoring and enhancing blood safety within blood bank operations....
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Challenges in collecting information on sexual orientation and gender identity for cancer patients: perspectives of hospital and central cancer registry abstractors
PurposeSexual and gender minority (SGM) populations experience cancer treatment and survival disparities; however, inconsistent sexual orientation...
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Automation of Wilms’ tumor segmentation by artificial intelligence
Background3D reconstruction of Wilms’ tumor provides several advantages but are not systematically performed because manual segmentation is extremely...
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Lipoleiomyosarcoma Presenting as Massive Retroperitoneal Mass: An Unusual Soft Tissue Tumor of Abdomen and its Review of Literature
Lipoleiomyosarcoma is a malignant tumor of both mesenchymal and smooth muscle origin. Lipoleiomyosarcoma is a very rare type of retroperitoneal...
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Hodgkin lymphoma and liquid biopsy: a story to be told
Hodgkin lymphoma (HL) represents a neoplasm primarily affecting adolescents and young adults, necessitating the development of precise diagnostic and...
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Financial toxicity, co** strategies, and quality of life among Chinese patients with hematologic malignancies: a cross-sectional study
PurposeFinancial toxicity is used to describe the financial hardship experienced by cancer patients. Financial toxicity may cause negative...
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The significance of lipid metabolism reprogramming of tumor-associated macrophages in hepatocellular carcinoma
In the intricate landscape of the tumor microenvironment, tumor-associated macrophages (TAMs) emerge as a ubiquitous cellular component that...
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Engineered CD147-CAR macrophages for enhanced phagocytosis of cancers
Chimeric antigen receptor (CAR) T cell therapy has shown promising results in hematologic malignancies, but its effectiveness in solid cancers...
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Tumor-intrinsic IFNα and CXCL10 are critical for immunotherapeutic efficacy by recruiting and activating T lymphocytes in tumor microenvironment
Tumor immunotherapies targeting PD-(L)1 exhibit anti-tumor efficacy in only 10–30% of patients with various cancers. Literature has demonstrated that...
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Effect of Multimodal Prehabilitation on Muscle Mass in Rectal Cancer Patients Receiving Neoadjuvant Treatment
Colorectal cancer is the second most prevalent type of cancer in the world. Surgical complications occur in up to 50% of patients which results in...
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Prognostic Impact of Inflammation-Based Factors in Patients with Esophageal Squamous Cell Carcinoma Achieving Pathological Complete Response After Neoadjuvant Chemoradiotherapy Followed by Surgery
BackgroundPatients achieving pathological complete response (pCR) post-neoadjuvant chemoradiotherapy (nCRT) and surgery for locally advanced...
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γδ T cells in human colon adenocarcinomas comprise mainly Vδ1, Vδ2, and Vδ3 cells with distinct phenotype and function
Γδ T cell infiltration into tumours usually correlates with improved patient outcome, but both tumour-promoting and tumoricidal effects of γδ T cells...
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A randomized phase II clinical trial of stereotactic body radiation therapy (SBRT) and systemic pembrolizumab with or without intratumoral avelumab/ipilimumab plus CD1c (BDCA-1)+/CD141 (BDCA-3)+ myeloid dendritic cells in solid tumors
BackgroundRadiotherapy (RT) synergizes with immune checkpoint blockade (ICB). CD1c(BDCA-1) + /CD141(BDCA-3) + myeloid dendritic cells (myDC) in the...
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Clinical application of a GPU-accelerated monte carlo dose verification for cyberknife M6 with Iris collimator
PurposeTo apply an independent GPU-accelerated Monte Carlo (MC) dose verification for CyberKnife M6 with Iris collimator and evaluate the dose...
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Intraparotid Sentinel Lymph Node Dissection for Melanoma: A Systematic Review and Meta-Analysis
BackgroundSurgical management of head and neck cutaneous melanoma (HNCM) has evolved tremendously since sentinel lymph node biopsy (SLNB) has become...
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Surgery for Locally Advanced Pancreatic Cancer Following Induction Chemotherapy: A Single-Center Experience
BackgroundThe use of surgery in patients with locally advanced pancreatic cancer (LAPC) following induction chemotherapy is increasing. However, most...
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RIP3 orchestrates oxidative stress and pyroptosis in doxorubicin-induced cardiotoxicity through regulation of AKT/Nrf2 signaling cascade
This study was designed to explore the role of RIP3 in DOX-induced cardiotoxicity and its underlying molecular mechanisms. Our results demonstrate...
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Systemtherapie des Magenkarzinoms im Stadium IV – aktuelle Entwicklungen
BackgroundSystemic treatment of metastatic or unresectable gastric cancer, including esophagogastric junction adenocarcinoma, has developed since...