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  1. DAP12 interacts with RER1 and is retained in the secretory pathway before assembly with TREM2

    DNAX-activating protein of 12 kDa (DAP12) is a transmembrane adapter protein expressed in lymphoid and myeloid lineage cells. It interacts with...

    Yanxia Liu, Sandra Theil, ... Jochen Walter in Cellular and Molecular Life Sciences
    Article Open access 15 July 2024
  2. The Material-Independent Signatures of Life.Forensic Tools of Astrobiology

    Biological life is intimately related to the geochemical conditions on Earth and is fit for this planet’s energy flux. It has often been suggested...
    Chapter
  3. The Early History of Bioenergy

    Energy is most commonly defined as the potential to do work. The maintenance of the living state requires a constant flow of energy through the...
    Chapter
  4. Assembling the Early Puzzle of Life

    So far no theory, no approach, no set of formulas, and no blackboard scheme have been found satisfactory in explaining the origin of life. The...
    Chapter
  5. The Early History of Bio-Information

    In a general sense, the information level of a structure equals the minimum number of instructions needed to specify the structure (Orgel 1973). The...
    Chapter
  6. Deconvolution Microscopy

    Since its introduction in 1983, deconvolution microscopy has become a key image-processing tool for visualizing the cellular structures of fixed and...
    Jean-Baptiste Sibarita in Microscopy Techniques
    Chapter
  7. Total Internal Reflection Fluorescence Microscopy in Single Molecule Nanobioscience

    Recent development in total internal reflection fluorescence microscopy (TIRFM) has made it possible to directly monitor the behaviors of...
    Tetsuichi Wazawa, Masahiro Ueda in Microscopy Techniques
    Chapter
  8. Tracking Movement in Cell Biology

    This article is an overview of techniques for measuring movement of proteins, vesicles and cells using digital image processing. Diverse techniques...
    Kota Miura in Microscopy Techniques
    Chapter
  9. Fluorescence Lifetime Imaging Microscopy (FLIM)

    Fluorescence lifetime imaging microscopy (FLIM) is a technique to map the spatial distribution of nanosecond excited state lifetimes within...
    Erik B. van Munster, Theodorus W. J. Gadella in Microscopy Techniques
    Chapter
  10. Spectral Imaging and Linear Unmixing in Light Microscopy

    Fluorescence microscopy is an essential tool for modern biological research. The wide range of available fluorophores and labeling techniques allows...
    Timo Zimmermann in Microscopy Techniques
    Chapter
  11. Degradation and Preservation of Organic Matter in Marine Sediments

    Organic matter that is deposited in aquatic sediments is subject to an intense diagenetic reactor that determines how much organic carbon is...
    Stuart G. Wakeham, Elizabeth A. Canuel in Marine Organic Matter: Biomarkers, Isotopes and DNA
    Chapter
  12. Higher Harmonic Generation Microscopy

    Higher harmonic-generation, including second harmonic generation and third harmonic generation, leaves no energy deposition to the interacted matters...
    Chi-Kuang Sun in Microscopy Techniques
    Chapter
  13. Map** of Aegilops speltoides derived leaf rust and stripe rust resistance genes using 35K SNP array

    Wheat is an essential food commodity cultivated throughout the world. However, this crop faces continuous threats from fungal pathogens, leaf rust...

    Balihar Kaur, Bukke Kutti Bai, ... Satinder Kaur in BMC Genomic Data
    Article Open access 15 July 2024
  14. Vitamin C inactivates c-Jun N-terminal kinase to stabilize heart and neural crest derivatives expressed 1 (Hand1) in regulating placentation and maintenance of pregnancy

    Vitamin C (VC) serves as a pivotal nutrient for anti-oxidation process, metabolic responses, and stem cell differentiation. However, its precise...

    Haibin Zhu, Huan Luo, ... Hongfeng Ruan in Cellular and Molecular Life Sciences
    Article Open access 15 July 2024
  15. Biological Markers for Anoxia in the Photic Zone of the Water Column

    In this chapter we review the current state of knowledge on the occurrence of anoxic conditions in the water column of past depositional systems...
    J. S. Sinninghe Damsté, S. Schouten in Marine Organic Matter: Biomarkers, Isotopes and DNA
    Chapter
  16. Controls on the Carbon Isotopic Compositions of Lipids in Marine Environments

    Organic carbon isotopes have long been used to study modern and ancient biogeochemical processes. Controls on the isotopic composition of organic...
    Richard D. Pancost, Mark Pagani in Marine Organic Matter: Biomarkers, Isotopes and DNA
    Chapter
  17. Sources and Cycling of Organic Matter in the Marine Water Column

    The organic carbon cycle operates on multiple time scales with a only small fraction of the global reservoir actively exchanged. For the marine...
    Chapter
  18. Molecular Tools for the Analysis of DNA in Marine Environments

    In the last decade, microbial ecologists have increasingly applied molecular techniques to investigate microorganisms in natural environments. The...
    R. Danovaro, C. Corinaldesi, ... A. Dell'Anno in Marine Organic Matter: Biomarkers, Isotopes and DNA
    Chapter
  19. Atmospheric Transport of Terrestrial Organic Matter to the Sea

    The transport of atmospheric particles with associated terrestrial organic matter to the oceans is an important process affecting various global...
    Chapter
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