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Drug-related emergency department visits: external validation of an assessment tool in a general emergency department population
BackgroundThe process of identifying drug-related hospitalisations is subjective and time-consuming. Assessment tool for identifying hospital...
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Breaking barriers: sha** global health futures with pilot and feasibility initiative
In the dynamic landscape of global health, the journey from a new development to its implementation is often fraught with challenges. Yet, it is...
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KLK7 expression in human tumors: a tissue microarray study on 13,447 tumors
BackgroundKallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and...
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Gender Differences in Perceptions of Psoriatic Arthritis Disease Impact, Management, and Physician Interactions: Results from a Global Patient Survey
IntroductionWe evaluated the impact of gender on disease severity, health-related quality of life (HRQoL), treatment management, and...
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A holistic lifestyle mobile health intervention for the prevention of type 2 diabetes and common mental disorders in Asian women with a history of gestational diabetes: a randomised control trial with 3-year follow-up protocol
BackgroundWomen with a history of gestational diabetes mellitus (GDM) are 12-fold more likely to develop type 2 diabetes (T2D) 4–6 years after...
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A case report and literature review: Mycobacterium leprae infection diagnosed by metagenomic next-generation sequencing of cerebrospinal fluid
BackgroundLeprosy is a chronic infectious disease caused by Mycobacterium leprae ( M. leprae ) that is responsible for deformities and irreversible...
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Progressive encephalomyelitis with rigidity and myoclonus: a pediatric case report and literature review
BackgroundProgressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare and life-threatening autoimmune disease of the central nervous...
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Low-dose tenecteplase during cardiopulmonary resuscitation in massive pulmonary embolism
We report the case of an 18-year-old male who presented to the Emergency Department with sudden onset dyspnea. The patient was intubated on arrival,...
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Genetics and sleep bruxism: a systematic review and meta-analysis of studies with twins
ObjectiveTo systematically review the literature regarding the concordance of sleep bruxism (SB) between monozygotic (MZ) and dizygotic (DZ) twins.
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DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition
IntroductionIntrauterine adhesions (IUA) manifest as endometrial fibrosis, often causing infertility or recurrent miscarriage; however, their...
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Can photoperiod improve growth performance and antioxidant responses of pacu (Piaractus mesopotamicus) reared in recirculation aquaculture systems?
The present study investigated the best photoperiod for culturing pacu ( Piaractus mesopotamicus ) in recirculation aquaculture systems (RAS) based on...
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Treatment Strategies for Filamentous Fungi Keratitis
IntroductionThis research aims to describe clinical findings, epidemiology and treatment outcomes in patients with filamentous fungi keratitis of a...
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Identification of purinergic system components in the venom of Bothrops mattogrossensis and the inhibitory effect of specioside extracted from Tabebuia aurea
Snake bites are a severe problem in the countryside of Brazil and are usually attributed to snakes of the genera Bothrops, Crotalus , and Lachesis ....
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In-Vitro Study of the Binding of Atorvastatin with Adenine using Multi-Spectroscopic Approaches
Atorvastatin—an oral lipid regulating drug is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase), which...
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The effect of Empagliflozin on echocardiographic parameters in diabetic patients after acute myocardial infarction: A systematic review and meta-analysis with trial sequential analysis
Patients with diabetes mellitus (DM) are at higher risk of cardiovascular events, particularly acute myocardial infarction (MI). Sodium-glucose...
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Biomarkers In Prediction of Acute Mesenteric Ischaemia: a prospective multicentre study (BIPAMI study): a study protocol
BackgroundAcute mesenteric ischaemia (AMI) is a life-threatening disease where early diagnosis is critical to avoid morbidity and mortality from...
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Alternate levels versus all levels mini-plate fixation in C3-6 cervical laminoplasty: a retrospective comparative study
ObjectiveThe purpose of this study is to compare radiological and clinical outcomes between alternate levels (C4 and C6) and all levels mini-plate...
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Central nervous system-associated macrophages modulate the immune response following stroke in aged mice
Age is a major nonmodifiable risk factor for ischemic stroke. Central nervous system-associated macrophages (CAMs) are resident immune cells located...
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App-based telerehabilitation program for older adults on waiting list for physiotherapy after hospital discharge: a feasibility pragmatic randomized trial
BackgroundInactivity while waiting for outpatient physiotherapy worsens the physical deconditioning of older adults after hospital discharge....
