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Carbon-ion radiotherapy alone vs. standard dose photon radiation with carbon-ion radiotherapy boost for high-grade gliomas: a retrospective study
BackgroundThis study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion...
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Physiological and cellular mechanisms of ischemic preconditioning microRNAs-mediated in underlying of ischemia/reperfusion injury in different organs
Ischemia–reperfusion (I/R) injury, as a pathological phenomenon, takes place when blood supply to an organ is disrupted and then aggravated during...
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A glimpse into viral warfare: decoding the intriguing role of highly pathogenic coronavirus proteins in apoptosis regulation
Coronaviruses employ various strategies for survival, among which the activation of endogenous or exogenous apoptosis stands out, with viral proteins...
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Key genes and molecular mechanisms related to Paclitaxel Resistance
Paclitaxel is commonly used to treat breast, ovarian, lung, esophageal, gastric, pancreatic cancer, and neck cancer cells. Cancer recurrence is...
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Therapeutic nucleic acids in regenerative medicine and tissue repair
In the vanguard of biomedical innovation, regenerative medicine emerges as a transformative paradigm, concentrating its efforts on rectifying tissue...
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Intricate effects of post-translational modifications in liver cancer: mechanisms to clinical applications
Liver cancer is a significant global health challenge, with hepatocellular carcinoma (HCC) being the most prevalent form, characterized by high...
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Lnc PVT1 facilitates TGF-β1-induced human cardiac fibroblast activation in vitro and ISO-induced myocardial fibrosis in vivo through regulating MYC
Cardiac fibrosis is a commonly seen pathophysiological process in various cardiovascular disorders, such as coronary heart disorder, hypertension,...
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Fluorescence Recognition of Hydrazine Driven by Neighboring Group Participation
Hydrazine (N 2 H 4 ) has toxic effects on the environment. Although a variety of reactive probes have been used to identify hydrazine, practical...
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Lessons Learned Implementing Syringe Services Programs at Rural Health Departments in Kentucky
Until recently, most syringe services programs (SSPs) in the United States operated in metropolitan areas. This study explores how SSP implementers...
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GPR116 alleviates acetaminophen-induced liver injury in mice by inhibiting endoplasmic reticulum stress
BackgroundAcetaminophen (APAP) overdose is a significant contributor to drug-induced liver injury worldwide. G-protein–coupled receptor 116 (GPR116)...
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Investigating distinct clinical features and constructing a nomogram model for survival probability in adults with cerebellar high-grade gliomas
BackgroundThe clinical features of cerebellar high-grade gliomas (cHGGs) in adults have not been thoroughly explored. This large-scale,...
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Integrative metagenomic, transcriptomic, and proteomic analysis reveal the microbiota-host interplay in early-stage lung adenocarcinoma among non-smokers
BackgroundThe incidence of early-stage lung adenocarcinoma (ES-LUAD) is steadily increasing among non-smokers. Previous research has identified...
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Benzothiazole-Quinoline-Based Fluorescent Probe for Fe3+ and its Applications in Environmental and Biological Samples
Due to the its high abundance, iron ion contamination and toxicity is one of the most challenging issue for living beings. Although, iron is...
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Rare tumours of the pancreas: monocentric study
PurposeThe biology of rare pancreatic tumours, which differs from that of ductal pancreatic cancer, requires increased attention. Although the...
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Illuminating the Power of V2O5 Nanoparticles: Efficient Photocatalytic Degradation of Organic Dyes under Visible Light
This research explores the synthesis, characterization, and application of Vanadium Pentoxide nanoparticles (V 2 O 5 NPs), focusing on their efficacy in...
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Systematic review: genetic polymorphisms in the pharmacokinetics of high-dose methotrexate in pediatric acute lymphoblastic leukemia patients
Variations in pharmacokinetic responses to high-dose methotrexate are essential for the prognosis and management of toxicity in the treatment of...
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Association of low adherence to weekly cisplatin with outcomes in patients with head and neck squamous cell carcinoma: a retrospective cohort study
BackgroundThe National Comprehensive Cancer Network (NCCN) guideline recommends consideration of weekly cisplatin as an alternative option for...
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CCT6A promotes cell proliferation in colon cancer by targeting BIRC5 associated with p53 status
Chaperonin-containing TCP1 (CCT) is a multi-subunit complex, known to participate the correct folding of many proteins. Currently, the mechanism...
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Malaria prevalence and transmission in the Zakpota sub-district of central Benin: baseline characteristics for a community randomised trial of a new insecticide for indoor residual spraying
BackgroundMalaria transmission is known to be perennial and heterogeneous in Benin. Studies assessing local malaria prevalence, transmission levels...
