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Knockout Transporter Cell Lines to Assess Substrate Potential Towards Efflux Transporters
P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and multidrug resistance transporter 2 (MRP2) are efflux transporters involved in the...
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Examining temporal changes in model-optimized parameters using longitudinal hemodynamic measurements
BackgroundWe previously applied hemodynamic data to personalize a mathematical model of the circulation expressed as physically interpretable...
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Combining app-based behavioral therapy with electronic cigarettes for smoking cessation: a study protocol for a single-arm mixed-methods pilot trial
BackgroundCigarette smoking remains a leading cause of preventable illness and death, underscoring the need for effective evidence-based smoking...
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Hydrogels for Musculoskeletal Tissue Engineering
The advancements in scaffold-supported cell therapy for musculoskeletal tissue engineering have been truly dramatic in the last couple of decades....
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Analysis and Architecture of Clinical Workflow Systems using Agent-Oriented Lifecycle Models
Healthcare executives are grappling with a climate of great change in the healthcare industry. This is coming from a number of sources. First, there...
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Current Status of Computerized Decision Support Systems in Mammography
Breast cancer is one of the most devastating and deadly diseases for women today. Despite advances in cancer treatment, early mammographic detection...
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13 Usability of an Assistive Robot Manipulator: Toward a Quantitative User Evaluation
This chapter describes our research activity on the integration of a robotic arm in the environment of persons with disabilities. People who have...
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2 Rehabilitation Robotics from Past to Present – A Historical Perspective
Popular culture presents the image of a robot as a mechanical, humanoid device, often evil in intent. Those with a slightly more informed technical...
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12 Risk Reduction Mechanisms for Safe Rehabilitation Robots
Safety is one of the most important features of rehabilitation robots. However, strategies for safe rehabilitation robots are not yet clarified. A...
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4 Welfare-Oriented Service Robotic Systems: Intelligent Sweet Home & KARES II
Utopia – it would be a society where the welfare of the people is properly guaranteed. In the society, each constituent would live his/her life with...
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5 “FRIEND” – An Intelligent Assistant in Daily Life
The research and development in the field of rehabilitation robots produced a multiplicity of rehabilitation robots available as off-the- shelf...
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6 GIVING-A-HAND System: The Development of a Task-Specific Robot Appliance
The rapidly changing demographics in industrialized nations create a pressing need for effective personal assistive aids that appeal to elderly and...
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10 A Safety Strategy for Rehabilitation Robots
It was reported previously that many MANUS users thought that the MANUS was useful, but not useful enough to gain totally independent lifestyles for...
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14 Processes for Obtaining a “Manus” (ARM) Robot within the Netherlands
This chapter describes both the current (Anno Domini 2003) and future processes of prescribing the Assistive Robotic Manipulator (ARM, also known as...
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11 Safety Evaluation Method of Rehabilitation Robots
An aged society comes soon. Human-care robots must be realized to nurse aged and disabled persons. Human-care robot will need to work around elderly...
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26 STRING-MAN: A Novel Wire Robot for Gait Rehabilitation
This paper presents a novel robotic prototype for advanced gait rehabilitation. This system integrates sophisticated robotic technology with control...
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Environmental Oxidative Stress – Environmental Sources of ROS
Environmental factors are known sources for oxidative stress. In consequence of the numerous influences that define our environment, environmental...
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Endogenous Oxidant-Generating Systems
Although organisms respiring air oxygen use their energy sources in an optimal way they are threatened by the compulsory formation of reactive oxygen...
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Low Molecular Weight Antioxidants
Low molecular weight antioxidants are an important part of the antioxidative defense mechanisms of cells and organisms. This chapter gives a short...