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The quassinoids bruceines A–M: pharmacology, mechanism of action, synthetic advance, and pharmacokinetics—a review
Bruceines A–L are among the quassinoid representatives found in the medicinal plant Brucea javanica (L.). An overview of their pharmacological...
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Clarifying middle authorship contributions to reduce abuses in science publishing and assessment of top-ranked SJR biochemistry and pharmacology journals’ authorship criteria
So-called “middle authors,” being neither the first, last, nor corresponding author of an academic paper, have made increasing relative contributions...
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Imaging features of pediatric meningiomas: emphasis on unusual locations
PurposeThis article aims to analyze pediatric meningioma’s imaging characteristics, especially those in unusual locations.
MethodsPediatric patients...
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Strategies for modeling aging and age-related diseases
The ability to reprogram patient-derived-somatic cells to IPSCs (Induced Pluripotent Stem Cells) has led to a better understanding of aging and...
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Glycogenolysis-Induced Astrocytic Ser**1 Expression Regulates Neuroinflammatory Effects on Hippocampal neuron
The bacterial pathogen, lipopolysaccharide (LPS), elicits microglial response and induces cytokine secretion that subsequently activates astrocytes....
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Awake craniotomy in pediatric low-grade glioma: barriers and future directions
IntroductionThe goal of surgical management in pediatric low-grade gliomas (pLGGs) is gross total resection (GTR), as it is considered curative with...
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Immune responses to oligomeric α-synuclein in Parkinson’s disease peripheral blood mononuclear cells
Parkinson’s disease displays clinical heterogeneity, presenting with motor and non-motor symptoms. Heterogeneous phenotypes, named brain-first and...
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CSF formation rate—a potential glymphatic flow parameter in hydrocephalus?
BackgroundStudies indicate that brain clearance via the glymphatic system is impaired in idiopathic normal pressure hydrocephalus (INPH). This has...
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Joint impact of polygenic risk score and lifestyles on early- and late-onset cardiovascular diseases
Understanding the interactions between genetic risk and lifestyles on different types and age onsets of cardiovascular disease (CVD) risk can help...
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A deep learning based cognitive model to probe the relation between psychophysics and electrophysiology of flicker stimulus
The flicker stimulus is a visual stimulus of intermittent illumination. A flicker stimulus can appear flickering or steady to a human subject,...
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The combination operation of grou** and ensemble coding for structured biological motion crowds in working memory
Massive studies have explored biological motion (BM) crowds processing for their remarkable social significance, primarily focused on uniformly...
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Neurological and Psychiatric Clinical Manifestations of Sjögren Syndrome
Purpose of ReviewSjögren Syndrome is a systemic autoimmune disorder that presents mainly with sicca symptoms, but frequently affects other body...
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Investigating the Impact of Intracerebroventricular Streptozotocin on Female Rats with and without Ovaries: Implications for Alzheimer’s Disease
To contribute to research on female models of Alzheimer’s disease (AD), our aim was to study the effect of intracerebroventricular (ICV) injection of...
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Epicatechin as a promising agent against arsenic-induced neurobehavioral toxicity in NMRI mice: behavioral and biochemical alterations
Epicatechin (Epi) is one of the most abundant flavonoids present in different fruits and tea leaves. Emerging research illuminates the promising...
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COVID-19-Associated Cerebellar Ataxia: A Case Series
COVID-19-associated cerebellar ataxia has rarely been reported and its clinical characteristics remain understudied. This study aims to report...
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Pediatric shunt failure in a resource limited Lower-Middle Income Country (LMIC) institution in La Paz, Bolivia
BackgroundShunt failure is an undesirable but common occurrence following neurosurgical shunting for pediatric hydrocephalus. Little is known about...
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Investigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization
It is unclear whether poverty and mental illness are causally related. Using UK Biobank and Psychiatric Genomic Consortium data, we examined evidence...
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Improving Likert scale big data analysis in psychometric health economics: reliability of the new compositional data approach
Bipolar psychometric scales data are widely used in psychologic healthcare. Adequate psychological profiling benefits patients and saves time and...
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Use of cortical hemodynamic responses in digital therapeutics for upper limb rehabilitation in patients with stroke
BackgroundStroke causes long-term disabilities, highlighting the need for innovative rehabilitation strategies for reducing residual impairments....
