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Deep 3D histology powered by tissue clearing, omics and AI
To comprehensively understand tissue and organism physiology and pathophysiology, it is essential to create complete three-dimensional (3D) cellular...
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A roadmap for ribosome assembly in human mitochondria
Mitochondria contain dedicated ribosomes (mitoribosomes), which synthesize the mitochondrial-encoded core components of the oxidative phosphorylation...
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Pathogenomics analysis of high-risk clone ST147 multidrug-resistant Klebsiella pneumoniae isolated from a patient in Egypt
BackgroundThe emergence of multi-drug-resistant Klebsiella pneumoniae (MDR-KP) represents a serious clinical health concern. Antibiotic resistance...
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Resolving chaperone-assisted protein folding on the ribosome at the peptide level
Protein folding in vivo begins during synthesis on the ribosome and is modulated by molecular chaperones that engage the nascent polypeptide. How...
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Green synthesis of zinc oxide nanoparticles (ZnO-NPs) by Streptomyces baarnensis and its active metabolite (Ka): a promising combination against multidrug-resistant ESKAPE pathogens and cytotoxicity
Various eco-friendly techniques are being researched for synthesizing ZnO-NPs, known for their bioactivity. This study aimed at biosynthesizing...
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Evaluating the probiotic effects of spraying lactiplantibacillus plantarum P-8 in neonatal piglets
BackgroundGut microbes play an important role in the growth and health of neonatal piglets. Probiotics can promote the healthy growth of neonatal...
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Biocontrol potential and growth-promoting effect of endophytic fungus Talaromyces muroii SD1-4 against potato leaf spot disease caused by Alternaria alternata
BackgroundAlternaria alternata is the primary pathogen of potato leaf spot disease, resulting in significant potato yield losses globally....
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Design of a two functional permeable reactive barrier for synergistic enzymatic and microbial bioremediation of phenol-contaminated waters: laboratory column evaluation
The present study aimed to develop a system using a combination of enzymatic and microbial degradation techniques for removing phenol from...
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An Overview of Tsetse Fly Repellents: Identification and Applications
Tsetse flies are vectors of the parasite trypanosoma that cause the neglected tropical diseases human and animal African trypanosomosis....
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Evaluation of vaccine candidates against Rhodococcus equi in BALB/c mice infection model: cellular and humoral immune responses
Rhodococcus equi ( R. equi ) is a zoonotic opportunistic pathogen that mainly causes fatal lung and extrapulmonary abscesses in foals and...
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VCP/p97-associated proteins are binders and debranching enzymes of K48–K63-branched ubiquitin chains
Branched ubiquitin (Ub) chains constitute a sizable fraction of Ub polymers in human cells. Despite their abundance, our understanding of branched Ub...
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Evaluating the effects of temperature and agitation on biofilm formation of bacterial pathogens isolated from raw cow milk
ObjectivesTo study the effect of agitation and temperature on biofilm formation (cell aggregates embedded within a self-produced matrix) by...
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Genomic characterization of multi drug resistant ESBL-producing Escherichia coli isolates from patients and patient environments in a teaching hospital in Ghana
BackgroundESBL-producing Escherichia coli pose a growing health risk in community and healthcare settings. We investigated the resistome, virulome,...
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Effects of Physiological Status and Environmental Factors on the Lure Responses of Three Pest Fruit Fly Species (Diptera: Tephritidae)
Biotic and abiotic factors influence how insects respond to stimuli. This can make it challenging to interpret captures in traps used to monitor pest...
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Horizontal gene transfer of the Mer operon is associated with large effects on the transcriptome and increased tolerance to mercury in nitrogen-fixing bacteria
BackgroundMercury (Hg) is highly toxic and has the potential to cause severe health problems for humans and foraging animals when transported into...
