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Integration of Explicit and Implicit Knowledge in Hybrid Intelligent Systems
The introduction of modular networks into fuzzy systems provides new insights into the integration of explicit and implicit knowledge in a...
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Practical Implementation Aspects Regarding Real-World Application of Hybrid Intelligent Systems
This chapter is focussed on the application aspects of HISengineering. The main application areas of HIS are mentioned. A lot of outstanding...
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Intelligent Techniques and Computational Intelligence
The field of Intelligent Technologies (IT) or Computational Intelligence (CI) is mainly the result of an increasing merger of Fuzzy Systems(FS) or...
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Neuro-Fuzzy Integration in Hybrid Intelligent Systems
In the last fifteen years, hybrid neural systems have drawn increasing research interest. This approach has been successfully used in various areas,...
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Neuro-Fuzzy Based Hybrid Intelligent Systems for Fault Diagnosis
In the last ten years, the field of diagnosis has attracted the attention of many researchers, both from the technical area as well as from the...
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Integration of metabolic and signaling networks
This contribution addresses the construction of mathematical models that provide a combined description of metabolic and regulatory processes within...
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Metabolic Control Analysis
Metabolic Control Analysis (MCA) is a theoretical framework for investigating and understanding control and regulation of metabolism. In particular,...
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No music without melody: How to understand biochemical systems by understanding their dynamics
The dynamics of the concentration of biochemical species is a systems property that arises through the interaction of metabolites and other...
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Mesoscopic kinetics and its applications in protein synthesis
Molecular biology emerged through unification of genetics and nucleic acid chemistry that took place with the discovery of the double helix (Watson...
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Kinetic modelling of the E. coli metabolism
We describe a general strategy that enables us to develop kinetic models of large-scale metabolic systems by collecting and using available metabolic...
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Metabolic networks: biology meets engineering sciences
A hallmark of systems biology is the interdisciplinary approach to the complexity of biological systems, in which mathematical modeling constitutes...
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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive...
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Mesomelia-synostoses syndrome: contiguous deletion syndrome, SULF1 haploinsufficiency or enhancer adoption?
BackgroundMesomelia-Synostoses Syndrome (MSS)(OMIM 600,383) is a rare autosomal dominant disorder characterized by mesomelic limb shortening, acral...
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Fragile X Syndrome and FMR1 premutation: results from a survey on associated conditions and treatment priorities in Italy
Background and objectivesFragile X Syndrome (FXS) is the most common cause of inherited intellectual disability, caused by CGG-repeat expansions...
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Exosome theranostics: Comparative analysis of P body and exosome proteins and their mutations for clinical applications
Exosomes are lipid-bilayered vesicles, originating from early endosomes that capture cellular proteins and genetic materials to form multi-vesicular...
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Basal FSH values are positively associated with aneuploidy incidence in pre-advanced maternal age (AMA) but not in AMA patients
PurposeTo assess the impact of maternal age on the association between maternal basal FSH and aneuploidy.
MethodsA retrospective study including...
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Gut Microbiota in Primary Osteoporosis: a Systematic Review
The link between gut microbiota (GM) and primary osteoporosis has garnered substantial attention. In this study, we conducted a systematic review...
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Enrichment of cell cycle pathways in progesterone-treated endometrial organoids of infertile women compared to fertile women
PurposeTo investigate whether the transcriptome profile differs between progesterone-treated infertile and fertile endometrial organoids.
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Comprehensive Quality Analysis of Conventional and Novel Biomarkers in Diagnosing and Predicting Prognosis of Coronary Artery Disease, Acute Coronary Syndrome, and Heart Failure, a Comprehensive Literature Review
Coronary artery disease (CAD), acute coronary syndrome (ACS), and heart failure (HF) are major global health issues with high morbidity and mortality...
