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Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition
Current cardiometabolic disease prevention guidelines recommend increasing dietary unsaturated fat intake while reducing saturated fats. Here we use...
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Identification of risk factors of Long COVID and predictive modeling in the RECOVER EHR cohorts
BackgroundSARS-CoV-2-infected patients may develop new conditions in the period after the acute infection. These conditions, the post-acute sequelae...
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Maternal distress, parenting stress, maladaptive parenting and children’s problematic media use in China: evidence from 2022 spring in Shanghai
The COVID-19 lockdown has forced young children to spend more time on media and significantly impacted their mothers’ mental health. This study...
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Insights from an N3C RECOVER EHR-based cohort study characterizing SARS-CoV-2 reinfections and Long COVID
BackgroundAlthough the COVID-19 pandemic has persisted for over 3 years, reinfections with SARS-CoV-2 are not well understood. We aim to characterize...
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Benmelstobart, anlotinib and chemotherapy in extensive-stage small-cell lung cancer: a randomized phase 3 trial
Immunochemotherapy is the first-line standard for extensive-stage small-cell lung cancer (ES-SCLC). Combining the regimen with anti-angiogenesis may...
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Development and validation of extraction and clean-up procedures for UPLC-MS/MS analysis of aflatoxins in spices
UPLC-MS/MS analytical conditions for the analysis of aflatoxins in spices were optimized and validated in this study. Liquid-liquid partition-based...
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Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways
Cardiac fibrosis following myocardial infarction (MI) seriously affects the prognosis and survival rate of patients. This study aimed to determine...
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Exploring barriers and solutions to consumer involvement in health service research using a nominal group technique
BackgroundConsumer involvement in health research is when patients, their families and caregivers work with researchers on research projects. Despite...
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Biological Evaluation of Lysionotin: a Novel Inhibitor of 5-Lipoxygenase for Anti-glioma
ObjectiveTo explore the potential mechanism of lysionotin in treating glioma.
MethodsFirst, target prediction based on Bernoulli Naïve Bayes...
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Electroacupuncture Alleviates Memory Deficits in APP/PS1 Mice by Targeting Serotonergic Neurons in Dorsal Raphe Nucleus
ObjectiveAlzheimer’s disease (AD) has become a significant global concern, but effective drugs able to slow down AD progression is still lacked....
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Paclitaxel in colon cancer management: from conventional chemotherapy to advanced nanocarrier delivery systems
Paclitaxel, a potent chemotherapeutic agent derived from the bark of the Pacific yew tree, has demonstrated significant efficacy in the treatment of...
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Sedentary behavior is associated with the mental health of university students during the Covid-19 pandemic, and not practicing physical activity accentuates its adverse effects: cross-sectional study
BackgroundMovement behaviours, such as sedentary behavior (SB) and physical inactivity, have become a public health issue due to their implications...
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An initial user model design for adaptive interface development in learning management system based on cognitive load
The cognitive aspect is crucial in develo** interactive and adaptive systems, including learning management systems (LMS). By understanding human...
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