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Kalanchoe pinnata (Lam.) Pers. Leaf ethanolic extract exerts selective anticancer activity through ROS-induced apoptotic cell death in human cancer cell lines
BackgroundThe leaves of Kalanchoe pinnata (Lam.) Pers. ( K. pinnata ), a succulent plant native to tropical regions, are used as a medicinal...
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A comparison of brown fat tissue related hormone levels in metabolically healthy and unhealthy individuals with obesity
PurposeOne of the key functions of brown adipose tissue is its positive impact on metabolism. This study aimed to examine the potential involvement...
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YAP/TAZ interacts with RBM39 to confer resistance against indisulam
The Hippo pathway and its downstream effectors, Yes-associated protein/transcriptional coactivator with PDZ-binding motif (YAP/TAZ), are essential...
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Importance of hospital and clinical factors for early mortality in Takotsubo syndrome: Insights from the Swedish Coronary Angiography and Angioplasty Registry
BackgroundTakotsubo syndrome (TTS) is an acute heart failure syndrome with symptoms similar to acute myocardial infarction. TTS is often triggered by...
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Deep transfer learning for detection of breast arterial calcifications on mammograms: a comparative study
IntroductionBreast arterial calcifications (BAC) are common incidental findings on routine mammograms, which have been suggested as a sex-specific...
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Challenges in the diagnosis and treatment of pure non-gestational uterine choriocarcinoma in a child: a case report
BackgroundDiagnosing non-gestational uterine choriocarcinoma in children is challenging because of its rarity and nonspecific imaging findings....
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Can we Predict Drug Excretion into Saliva? A Systematic Review and Analysis of Physicochemical Properties
Background and ObjectivesSaliva is a patient-friendly matrix for therapeutic drug monitoring (TDM) but is infrequently used in routine care. This is...
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The use of point of care gastric ultrasound and anesthesia management in pediatric patients with preoperative fasting non-adherence scheduled for elective surgical procedures: a retrospective study
BackgroundFailure to adhere to perioperative fasting requirements increases aspiration risk and can lead to delay or cancellation of surgery. Point...
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Sodium selenite attenuates inflammatory response and oxidative stress injury by regulating the Nrf2/ARE pathway in contrast-induced acute kidney injury in rats
BackgroundContrast-induced acute kidney injury (CI-AKI) is an acute renal complication that occurs after intravascular contrast agent administration....
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Diagnosis and treatment of secondary nephrotic syndrome with rash as the first symptom: a case report
BackgroundMembranous nephropathy (MN) is a common type of nephrotic syndrome (NS) in adults, accounting for about 20–30% of cases. Although secondary...
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The evolving role of pharmacists in depression care: a sco** review
BackgroundWorldwide, depression is known to contribute significantly to the global burden of disease. Considering pharmacists are among the most...
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Successful management of a delayed presentation of traumatic descending thoracic aorta pseudoaneurysm: a literature review based on a case report
BackgroundBlunt traumatic aortic injury (BTAI) is the second leading cause of death due to traumas in young patients. The primary presentation might...
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Ruthenibacterium lactatiformans isolated from a human blood culture: a first report
BackgroundRuthenibacterium lactatiformans, a Gram-stain-negative, rod-shaped, obligate anaerobic bacterium of the Oscillospiraceae family, has not...
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Implementing a no-drain policy for extraperitoneal colorectal anastomosis in a real-life setting: analysis of outcomes and surgeons’ adherence
AimRecent evidence has questioned the usefulness of anastomotic drain (AD) after low anterior resection (LAR). However, the implementation and...
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Effective strategies for pregnancy and lactation-associated osteoporosis: teriparatide use in focus
IntroductionPregnancy and lactation-associated osteoporosis (PLO) is a rare condition characterized by fragility fractures occurring during late...
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Prevalence of Tendon Rupture and Tendinopathies Among Patients with Atherosclerotic Cardiovascular Disease Derived From United States Administrative Claims Data
IntroductionThe prevalence of tendon rupture and tendinopathies (TRT) has not been determined in a large population of patients with atherosclerotic...
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Oncological features of sporadic vs. hereditary pediatric medullary thyroid cancer
PurposeNo genomic data have been put forth that prove beyond a shadow of doubt that sporadic medullary thyroid cancer (MTC) occurs in infancy,...
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PIM1/NF-κB/CCL2 blockade enhances anti-PD-1 therapy response by modulating macrophage infiltration and polarization in tumor microenvironment of NSCLC
Elevated infiltration of tumor-associated macrophages (TAMs) drives tumor progression and correlates with poor prognosis for various tumor types. Our...
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Intracranial dissemination of Klebsiella pneumoniae originating from pulmonary infection: a case report
BackgroundMetastatic brain abscesses caused by Klebsiella pneumoniae are extremely rare but life-threatening conditions. To depict a unique case of...
