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Cardiovascular history and risk of idiopathic Parkinson’s disease: a cross-sectional observational study
BackgroundParkinson's disease (PD), while often associated with its distinctive motor symptoms, can also exert a notable impact on the cardiovascular...
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Simulated complexes formed from a set of postsynaptic proteins suggest a localised effect of a hypomorphic Shank mutation
BackgroundThe postsynaptic density is an elaborate protein network beneath the postsynaptic membrane involved in the molecular processes underlying...
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Changes of brain functional network in Alzheimer’s disease and frontotemporal dementia: a graph-theoretic analysis
BackgroundAlzheimer’s disease (AD) and frontotemporal dementia (FTD) are the two most common neurodegenerative dementias, presenting with similar...
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Persistent vocal learning in an aging open-ended learner reflected in neural FoxP2 expression
BackgroundMost vocal learning species exhibit an early critical period during which their vocal control neural circuitry facilitates the acquisition...
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The angiotensin II receptors type 1 and 2 modulate astrocytes and their crosstalk with microglia and neurons in an in vitro model of ischemic stroke
BackgroundAstrocytes are the most abundant cell type of the central nervous system and are fundamentally involved in homeostasis, neuroprotection,...
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Diabetes mellitus and risk of incident dementia in APOE ɛ4 carriers: an updated meta-analysis
Background and aimDiabetes raises the risk of dementia, mortality, and cognitive decline in the elderly, potentially because of hereditary variables...
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Naturally sterile Mus spretus hybrids are suitable for the generation of pseudopregnant embryo transfer recipients
For the preparation of embryo transfer recipients, surgically vasectomized mice are commonly used, generated by procedures associated with pain and...
