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Modulation of gene expression in immune-related organs by in ovo stimulation with probiotics and prophybiotics in broiler chickens
In ovo stimulation has been studied intensively as an alternative to antibiotic use in poultry production. We investigated the potential use of a...
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Genome-wide analysis of histone modifications can contribute to the identification of candidate cis-regulatory regions in the threespine stickleback fish
BackgroundCis -regulatory mutations often underlie phenotypic evolution. However, because identifying the locations of promoters and enhancers in...
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Investigating the impact of different routes of nano and micro nickel oxide administration on rat kidney architecture, apoptosis markers, oxidative stress, and histopathology
Although the production and use of nickel oxide nanoparticles (NiONP) are widespread, environmental and public health problems are associated with...
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Identification of consensus homozygous regions and their associations with growth and feed efficiency traits in American mink
The recent chromosome-based genome assembly and the newly developed 70K single nucleotide polymorphism (SNP) array for American mink ( Neogale vison )...
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sciMET-cap: high-throughput single-cell methylation analysis with a reduced sequencing burden
DNA methylation is a key component of the mammalian epigenome, playing a regulatory role in development, disease, and other processes. Robust,...
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TFscope: systematic analysis of the sequence features involved in the binding preferences of transcription factors
Characterizing the binding preferences of transcription factors (TFs) in different cell types and conditions is key to understand how they...
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Development of a prognostic risk model of uveal melanoma based on N7-methylguanosine-related regulators
BackgroundUveal melanoma (UVM) stands as the predominant type of primary intraocular malignancy among adults. The clinical significance of...
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Using high-density SNP data to unravel the origin of the Franches-Montagnes horse breed
BackgroundThe Franches-Montagnes (FM) is the last native horse breed of Switzerland, established at the end of the 19th century by cross-breeding...
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Varroa destructor mite population dynamics in africanized honeybee (Apis mellifera) colonies in a semi-arid region
Most published data on mite infestation rates in semi-arid regions have been collected over only 3 or 4 months during a specific period of the year....
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Physiological responses of invasive round goby (Neogobius melanostomus) to environmental stressors across a latitudinal span
Ecosystems worldwide are struggling with increasingly high levels of human-induced stressors, impacting their ecological health at local, regional,...
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COQ7 splice site variant causing a spastic paraparesis phenotype in siblings
The COQ7 gene is one of the causative genes for primary COQ10 deficiency-related disorders. OMIM-related phenotypes include severe...
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The cerebellum modulates thirst
The cerebellum, a phylogenetically ancient brain region, has long been considered strictly a motor control structure. Recent studies have implicated...
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Whole-genome analysis reveals distinct adaptation signatures to diverse environments in Chinese domestic pigs
BackgroundLong-term natural and artificial selection has resulted in many genetic footprints within the genomes of pig breeds across distinct...
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Isolation and characterisation of two epithelial-like cell lines from the gills of Chrysophrys auratus (Australasian snapper) and Oncorhynchus tshawytscha (Chinook salmon) and their use in aquatic toxicology
In vitro gill models are becoming increasingly important in aquatic toxicology, yet the fish gill invitrome is underrepresented, encompassing...
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Comparative proteomics in tall fescue to reveal underlying mechanisms for improving Photosystem II thermotolerance during heat stress memory
BackgroundThe escalating impacts of global warming intensify the detrimental effects of heat stress on crop growth and yield. Among the earliest and...
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Dispel some mist on circulating biopterins: measurement, physiological interval and pathophysiological implication
Background and aimsBiopterins, including tetrahydrobiopterin (BH4), dihydrobiopterin (BH2), and biopterin (B), were crucial enzyme cofactors in vivo....
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Beauveria bassiana native strains affect the reproductive index of Rhipicephalus microplus ticks
Rhipicephalus microplus poses a significant economic threat due to its role in transmitting Babesia bigemina, B. bovis and Anaplasma marginale ....