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Association between antidepressant use and delirium in older adults: an analysis of the World Health Organization’s global pharmacovigilance database
BackgroundPsychoactive drugs frequently cause delirium adverse events in older adults. However, few data on the relationship between antidepressants...
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Universal Prevention of Dementia in Italy: A Document Analysis of the 21 Italian Regional Prevention Plans
BackgroundUp to 40% of dementia cases are theoretically avoidable and population-level interventions (i.e., universal prevention) are a key component...
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No Association Found: Adverse Childhood Experiences and Cognitive Impairment in Older Australian Adults
ObjectiveThis study aimed to investigate the relationship between childhood adversity and cognitive impairment in older adults.
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Acceptability and preliminary effects of the volunteer-supported Meaningful Moments program to engage older adults with advanced dementia on a hospital-based specialized dementia care unit: a mixed methods study
BackgroundNamaste Care offers practical skills for healthcare providers, volunteers, and families to meaningfully engage individuals with dementia in...
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Association between sleep duration and possible sarcopenia in middle-aged and elderly Chinese individuals: evidence from the China health and retirement longitudinal study
BackgroundSarcopenia is a common cause of disability in the aging population, and managing sarcopenia is an important step in building intrinsic...
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Atypical chronic myeloid leukemia found in a patient with eosinophilia for six years: a case report
BackgroundAtypical chronic myeloid leukemia (aCML) is a highly aggressive type of blood cancer that falls under the category of...
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The mouse Social Frailty Index (mSFI): a novel behavioral assessment for impaired social functioning in aging mice
Various approaches exist to quantify the aging process and estimate biological age on an individual level. Frailty indices based on an age-related...
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Self-perceptions of aging, physical activity, and depressive symptoms in older community residents with varied neighborhood walkability in Taiwan
BackgroundPrior research has identified the mediating effect of physical activity in the relationship between self-perceptions of aging and physical...
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Longitudinal analysis on inflammatory markers and frailty progression: based on the English longitudinal study of aging
PurposeFrailty is a common health state that is closely linked to adverse health outcomes in aging society. Although many inflammatory biomarkers...
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Age-related effects on absolute and relative isokinetic knee extensor strength in community-dwelling older men and women at a French geriatric day hospital
PurposeIsokinetic knee extensor strength is poorly evaluated in geriatric day hospitals (GDHs), despite its potential functional significance...
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Psychosocial and biological pathways to aging
While the biological hallmarks of aging are widely recognized as fundamental mechanisms of biological aging, more recently, there have been calls...
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Strategies for modeling aging and age-related diseases
The ability to reprogram patient-derived-somatic cells to IPSCs (Induced Pluripotent Stem Cells) has led to a better understanding of aging and...
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The impact of discharge letter content on unplanned hospital readmissions within 30 and 90 days in older adults with chronic illness – a mixed methods study
BackgroundCare transitions are high-risk processes, especially for people with complex or chronic illness. Discharge letters are an opportunity to...
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“Multidisciplinary fast-track” care can significantly reduce risk of mortality among hip fracture patients at least 80 years old: a single-center retrospective study
Background“Multidisciplinary fast-track” (MFT) care can accelerate recovery and improve prognosis after surgery, but whether it is effective in older...
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Examining Audiences’ Psychological Reactance to Christian-Sourced Excessive Alcohol Consumption Messages in the United States
This study experimentally investigated the effect of dogmatic and suggestive language in Christian-sourced excessive alcohol consumption messages...
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Self-Threatening Extortionists Constitute a Problem for Utilitarians, Not Contractualists
Johann Frick has claimed that morality requires that we (in many cases) should give in to the demands of rational agents who attempt to extort us by...
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Depressive symptoms as risk factors for the onset of home hypertension: a prospective cohort study
Depression is comorbid with somatic diseases; however, the relationship between depressive symptoms and hypertension (HT), a risk factor for...
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Effects of polygenic risk score and sodium and potassium intake on hypertension in Asians: A nationwide prospective cohort study
Genetic factors, lifestyle, and diet have been shown to play important roles in the development of hypertension. Increased salt intake is an...