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Development of Technetium-99m and Rhenium-188 Radiopharmaceuticals Containing a Terminal Metal–Nitrido Multiple Bond for Diagnosis and Therapy
The chemistry of nitrido complexes of technetium has played an important role in the search of new Tc-99m radiopharmaceuticals and in providing...
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Monitoring Multidrug Resistance P-Glycoprotein Drug Transport Activity with Single-Photon Emission Computed Tomography and Positron Emission Tomography Radiopharmaceuticals
Multidrug resistance (MDR) mediated by overexpression of MDR1 P-glycoprotein (Pgp) is one of the best characterized transporter-mediated barriers to...
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Radiopharmaceuticals for Positron Emission Tomography Imaging of Somatostatin Receptor Positive Tumors
The targeting of somatostatin receptors in tumors has been a goal in cancer treatment and diagnosis since the 1980s. Over the past two decades, great...
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Rhenium and Technetium Complexes Anchored by Phosphines and Scorpionates for Radiopharmaceutical Applications
This review presents a comprehensive overview of the most significant developments in the chemistry of technetium and rhenium complexes anchored by...
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6-Hydrazinonicotinamide Derivatives as Bifunctional Coupling Agents for 99mTc-Labeling of Small Biomolecules
99mTc-labeled small biomolecules are a class of receptor-based, target specific radiopharmaceuticals for the detection of various diseases, such as...
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Radiolabeled Integrin αvβ3 Antagonists as Radiopharmaceuticals for Tumor Radiotherapy
Integrins are a family of proteins that facilitate cellular adhesion to and migration on the extracellular matrix proteins found in intercellular...
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New Organometallic Technetium Complexes for Radiopharmaceutical Imaging
It is the objective of this review to introduce the reader to the current status of organometallic chemistry, oriented towards the development of...
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Challenges in diagnosis of calcaneal fractures: an examination using the WIDI SIM platform
IntroductionThe calcaneus is the most commonly fractured tarsal bone. Diagnosis is often challenging due to subtle radiographic changes and requires...
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Normal ovarian sizes on MRI in pediatric patients: a preliminary study
BackgroundOvarian enlargement is one of several findings of pathology, including ovarian torsion. With increasing use of MRI for acute abdominal pain...
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CT in musculoskeletal imaging: still helpful and for what?
Computed tomography (CT) is a common modality employed for musculoskeletal imaging. Conventional CT techniques are useful for the assessment of...
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A novel contact optimization algorithm for endomicroscopic surface scanning
PurposeProbe-based confocal laser endomicroscopy (pCLE) offers real-time, cell-level imaging and holds promise for early cancer diagnosis. However, a...
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Mitral complex geometric changes aggravate mitral stenosis after transcatheter aortic valve replacement
Severe aortic valve stenosis (AS) often coexists with mitral valve stenosis (MS). MS aggravation after transcatheter aortic valve replacement (TAVR)...
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Exploring the thalamus L-sign: initial findings and associations with white matter injury in premature infants
BackgroundThe thalamus L-sign, characterized by damage to the lateral and posterior parts of the thalamus, has recently been identified as a...
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Feasibility and success of a non-sedated brain MRI training protocol in 7-year-old children from rural and semi-rural Colombia
BackgroundBrain magnetic resonance imaging (MRI) is a crucial tool for clinical evaluation of the brain and neuroscience research. Obtaining...
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Association between mesenteric panniculitis and urolithiasis
BackgroundMesenteric panniculitis is a rare condition and refers to benign and nonspecific inflammation of mesenteric fat.
ObjectivesThis study...
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ConKeD: multiview contrastive descriptor learning for keypoint-based retinal image registration
AbstractRetinal image registration is of utmost importance due to its wide applications in medical practice. In this context, we propose ConKeD, a...
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Maternal diseases and congenital anomalies of the kidney and urinary tract in offspring: a cohort study
BackgroundCongenital anomalies of the kidneys and urinary tract (CAKUT) are the most common cause of prenatally diagnosed developmental malformation....
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Role of imaging in third aortic valve implantation: TAV-in-TAV-in-SAV
Coronary obstruction remains a primary concern for redo transcatheter aortic valve implantation (TAVI) due to supra-annular leaflets. Hereby, we...
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Sample size calculation for data reliability and diagnostic performance: a go-to review
Sample size, namely the number of subjects that should be included in a study to reach the desired endpoint and statistical power, is a fundamental...
