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Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were... -
Multivariate associations between neuroanatomy and cognition in unmedicated and medicated individuals with schizophrenia
Previous studies that focused on univariate correlations between neuroanatomy and cognition in schizophrenia identified some inconsistent findings....
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Plasma Biomarkers of Alzheimer’s Disease and Neurodegeneration According to Sociodemographic Characteristics and Chronic Health Conditions
Ultrasensitive assays have been developed which enable biomarkers of Alzheimer’s disease pathology and neurodegeneration to be measured in blood....
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What to Measure in Aneurysmal Subarachnoid Haemorrhage Research—An International Delphi Survey
Aneurysmal subarachnoid haemorrhage (aSAH) is a devastating condition with high mortality and morbidity. The outcome measures used in aSAH clinical...
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Development and validation of a risk prediction model for motoric cognitive risk syndrome in older adults
ObjectiveThe objective of this study was to develop a risk prediction model for motoric cognitive risk syndrome (MCR) in older adults.
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Inter-joint coordination with and without dopaminergic medication in Parkinson’s disease: a case-control study
BackgroundHow the joints exactly move and interact and how this reflects PD-related gait abnormalities and the response to dopaminergic treatment is...
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Intelligent ankle–foot prosthesis based on human structure and motion bionics
The ankle–foot prosthesis aims to compensate for the missing motor functions by fitting the motion characteristics of the human ankle, which...
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Aberrant telomeric structures and serum markers of telomere dysfunction in healthy aging: a preliminary study
Telomeres undergo a progressive shortening process as individuals age, and it has been proposed that severely shortened and dysfunctional telomeres...
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Benefits of a family-based care transition program for older adults after hip fracture surgery
BackgroundHip fracture (HF) in older adults is strongly associated with a greater decline in their activities of daily living (ADLs) and...
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Data-driven exploratory method investigation on the effect of dyslexia education at brain connectivity in Turkish children: a preliminary study
Dyslexia is a specific learning disability that is neurobiological in origin and is characterized by reading and/or spelling problems affecting the...
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Neuroprotective and vasoprotective effects of herb pair of Zhiqiao-Danggui in ischemic stroke uncovered by LC-MS/MS-based metabolomics approach
Ischemic stroke is the most important cause of disability and death worldwide, but current treatments remain limited. Traditional Chinese medicine...
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Assessment of Innovative Pharmacological Targets in Schizophrenia
Purpose of reviewSchizophrenia is a disorder with an approximate prevalence of 1% associated with great impairments in daily life functioning and...
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The influence of sex-specific factors on biological transformations and health outcomes in aging processes
The aging process demonstrates notable differences between males and females, which are key factors in disease susceptibility and lifespan. The...
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Microstructural characterization of multiple sclerosis lesion phenotypes using multiparametric longitudinal analysis
Background and objectivesIn multiple sclerosis (MS), slowly expanding lesions were shown to be associated with worse disability and prognosis. Their...
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Patients with complex and very-early-onset ATL1-related spastic paraplegia offer insights on genotype/phenotype correlations and support for autosomal recessive forms of SPG3A
Spastic paraplegia type 3A (SPG3A) is the second most common form of hereditary spastic paraplegia (HSP). This autosomal-dominant-inherited motor...
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Breathing difficulties in a nonagenarian: a self report
This is a self report. It is age related because I am 96 years old; about 5 years ago I was asymptomatic in this respect. I describe the difficulties...
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SWI/SNF Complex Connects Signaling and Epigenetic State in Cells of Nervous System
SWI/SNF protein complexes are evolutionarily conserved epigenetic regulators described in all eukaryotes. In metameric animals, the complexes are...
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MAMs and Mitochondrial Quality Control: Overview and Their Role in Alzheimer’s Disease
Alzheimer’s disease (AD) represents the most widespread neurodegenerative disorder, distinguished by a gradual onset and slow progression, presenting...
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Nerve Regeneration Through Differentiation of Endometrial-Derived Mesenchymal Stem Cells into Nerve-Like Cells Using Polyacrylonitrile/Chitosan Conduit and Berberine in a Rat Sciatic Nerve Injury Model
Nervous injuries are common in humans. One of the most advanced treatment methods is neural tissue engineering. This research aims to utilize...