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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive...
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Diabetic myonecrosis complicated by emphysematous pyomyositis and abscess caused by Escherichia coli: a case report
BackgroundNecrotizing myopathies and muscle necrosis can be caused by immune-mediated mechanisms, drugs, ischemia, and infections, and differential...
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Biologics or Janus Kinase Inhibitors in Rheumatoid Arthritis Patients Who are Insufficient Responders to Conventional Anti-Rheumatic Drugs
Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease which can induce progressive disability if not properly treated early....
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Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions
The applications of hydrogels have expanded significantly due to their versatile, highly tunable properties and breakthroughs in biomaterial...
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Classification of the oesophageal perforation
ObjectivesEsophageal perforations are a complex clinical scenario that have been poorly studied. To date, there is no grading of esophageal...
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From balance to imbalance: disruption of plasma glutathione concentration in micropapillary thyroid carcinoma
BackgroundDespite the presence of evidence that establishes a strong correlation between oxidative stress and thyroid cancer, there exists a scarcity...
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7 T and beyond: toward a synergy between fMRI-based presurgical map** at ultrahigh magnetic fields, AI, and robotic neurosurgery
Presurgical evaluation with functional magnetic resonance imaging (fMRI) can reduce postsurgical morbidity. Here, we discuss presurgical fMRI...
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BMA-based Mendelian randomization identifies blood metabolites as causal candidates in pregnancy-induced hypertension
Pregnancy-induced hypertension (PIH), a prominent determinant of maternal mortality and morbidity worldwide, is hindered by the absence of...
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Risk factors and predictors of recurrence of febrile seizures in children in Nantong, China: a retrospective cohort study
BackgroundAlthough most children with febrile seizures (FS) have a favorable prognosis, some experience recurrence within 1–3 years. Age, peak...
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A Randomized, Open-Label, Phase I, Single-Dose Study of Antisense Oligonucleotide, Vupanorsen, in Chinese Adults with Elevated Triglycerides
BackgroundVupanorsen is a GalNAc 3 -conjugated antisense oligonucleotide targeting angiopoietin-like 3 (ANGPTL3) mRNA shown to reduce atherogenic...
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Pulmonary metastatic gestational choriocarcinoma following an uncomplicated term pregnancy: a case report
BackgroundChoriocarcinoma is a highly malignant pregnancy-related trophoblastic neoplasm, characterized by early metastasis to the lungs. Therefore,...
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Correlation between circulating advanced glycation end products and thioredoxin-interacting protein levels and renal fat content in type 2 diabetes mellitus patients
BackgroundThis study sought to explore the clinical relevance of the associations of serum levels of advanced glycation end products (AGEs), soluble...
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Right perirenal urinoma and urinothorax in an infant after neonatal ablation of posterior urethral valve: A rare complication diagnosed by pleural aspiration and treated with perinephric drainage: a case report
ObjectiveUrinothorax and urinoma are rare complications of obstructive uropathy. They might occur due to persistent high back pressure on the renal...
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Sigmoid and cecum colon volvulus: a case report
IntroductionColon volvulus is the twisting of a segment of colon on its mesenteric axis, which can lead to the obstruction of the lumen and the blood...
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First-trimester hemoglobin, haptoglobin genotype, and risk of gestational diabetes mellitus in a retrospective study among Chinese pregnant women
BackgroundThis study aimed to assess whether the Haptoglobin (Hp) genotype influences the relationship between hemoglobin (Hb) levels and the...
