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Mining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning
BackgroundThe advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack...
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Clinical and genetic analysis of Niemann-Pick disease type C with a novel NPC1 variant
BackgroundNiemann-Pick disease type C poses a significant challenge within the landscape of rare genetic disorders, marked by its connection to...
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A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori
Helicobacter pylori ( H. pylori ) is currently recognized as the primary carcinogenic pathogen associated with gastric tumorigenesis, and its high...
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Health outcomes and healthcare utilization associated with four undiagnosed chronic conditions: evidence from nationally representative survey data in Sri Lanka
BackgroundLow awareness of chronic conditions raises the risk of poorer health outcomes and may result in healthcare utilization and spending in...
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A randomised controlled trial of Standard Of Care versus RadioAblaTion in Early Stage HepatoCellular Carcinoma (SOCRATES HCC)
BackgroundTherapeutic options for early-stage hepatocellular carcinoma (HCC) in individual patients can be limited by tumor and location, liver...
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Prospective investigation of amino acid transport and PSMA-targeted positron emission tomography for metastatic lobular breast carcinoma
PurposeTo explore the feasibility of imaging amino-acid transport and PSMA molecular pathways in the detection of metastatic breast invasive lobular...
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[18F]-D3FSP β-amyloid PET imaging in older adults and alzheimer’s disease
Purpose[ 18 F]-D3FSP is a new β-amyloid (Aβ) PET imaging tracer designed to decrease nonspecific signals in the brain by reducing the formation of the...
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Hydrogels for Musculoskeletal Tissue Engineering
The advancements in scaffold-supported cell therapy for musculoskeletal tissue engineering have been truly dramatic in the last couple of decades.... -
Virtual Reality in Healthcare
In our modern 21st century, daily life would be unthinkable without computers. Multimedia and virtual reality are useful for people with special... -
Access to Information on Demand by the aid of Digital Talking Books
This chapter addresses the concept and the fundamental ideas of the digital talking book (DTB), with a particular focus on DTBs in the DAISY format.... -
Effect of combined physical–cognitive training on the functional and cognitive capacity of older people with mild cognitive impairment: a randomized controlled trial
BackgroundThe increase in population aging highlights the growing prevalence of mild cognitive impairment, prompting the adoption of interventions...
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A longitudinal multi-centric cohort study assessing infant neurodevelopment delay among women with persistent postpartum depression in Nepal
BackgroundInfant neurodevelopment in the first years after birth is determined by multiple factors, including parental care and maternal mental...
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Diffuse pulmonary arteriovenous malformation presenting with secondary polycythemia and headaches: a case report
BackgroundPulmonary arteriovenous malformations are a relatively uncommon medical condition, affecting roughly 1 in every 2500 individuals. Of those...
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Breaking down barriers: rationalisations and motivation to stop among Chinese male smokers under cigarette dependence
BackgroundSmoking rationalisation beliefs are a huge barrier to quitting smoking. What types of rationalisations should be emphasised in smoking...
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Contact-force local impedance algorithm to guide effective pulmonary vein isolation in AF patients: 1-year outcome from an international multicenter clinical setting
BackgroundThe combination of highly localized impedance (LI) and contact force (CF) may improve tissue characterization and lesion prediction during...
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Polymeric Systems for Bioinspired Delivery of Angiogenic Molecules
Growth factors are increasingly utilized to promote regeneration of lost or compromised tissues and organs. However, current strategies applying... -
Biopolyesters in Tissue Engineering Applications
Tissue engineering is a rapidly growing interdisciplinary field of research focused on the development of vital autologous tissue through the use... -
Interfaces to Control Cell-Biomaterial Adhesive Interactions
Cell adhesion to adsorbed proteins and adhesive sequences engineered on surfaces is crucial to cellular and host responses to implanted devices,... -
Ubiquitous Healthcare: Technology and Service
Ubiquitous healthcare is introduced in terms of technology and service, considering the current technology as well as the future technology and...