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Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission
Dietary salt is increasingly recognized as an independent risk factor for cognitive impairment. However, the exact mechanisms are not yet fully...
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What to Measure in Aneurysmal Subarachnoid Haemorrhage Research—An International Delphi Survey
Aneurysmal subarachnoid haemorrhage (aSAH) is a devastating condition with high mortality and morbidity. The outcome measures used in aSAH clinical...
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COVID-related constrictive pericarditis requiring pericardiectomy: a case report
BackgroundThe COVID-19 pandemic was primarily considered a respiratory malady in the early phases of the outbreak. However, as more patients suffer...
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DNA Methylation-derived biological age and long-term mortality risk in subjects with type 2 diabetes
BackgroundIndividuals with type 2 diabetes (T2D) face an increased mortality risk, not fully captured by canonical risk factors. Biological age...
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Physiological and cellular mechanisms of ischemic preconditioning microRNAs-mediated in underlying of ischemia/reperfusion injury in different organs
Ischemia–reperfusion (I/R) injury, as a pathological phenomenon, takes place when blood supply to an organ is disrupted and then aggravated during...
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Relationship between the severity of functional mitral regurgitation at admission and one-year outcomes in patients hospitalized for acute heart failure with mildly reduced ejection fraction
BackgroundThe epidemiological distribution of functional mitral regurgitation (FMR) in heart failure (HF) and mildly reduced ejection fraction...
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Comparative analysis of del Nido cardioplegia versus blood cardioplegia in isolate coronary artery bypass grafting
BackgroundThis study examined the efficacy of del Nido cardioplegia compared with traditional blood cardioplegia in adult cardiac surgery for...
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Recognition of an extralobar pulmonary sequestration during lung resection
BackgroundExtralobar pulmonary sequestration is located outside the lung parenchyma and is covered by a separated pleural sac, which comprises...
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Lnc PVT1 facilitates TGF-β1-induced human cardiac fibroblast activation in vitro and ISO-induced myocardial fibrosis in vivo through regulating MYC
Cardiac fibrosis is a commonly seen pathophysiological process in various cardiovascular disorders, such as coronary heart disorder, hypertension,...
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Enhancing patient acceptance of ICD implantation through structured shared decision making: conversation is key
BackgroundImplantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy defibrillators (CRT-D) are lifesaving treatments for...
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Implantable cardiac monitor and leadless pacemaker in the management of syncope due to intermittent high-degree atrioventricular block: a case report
BackgroundLead dislodgements, tricuspid valve failure, and wound infections are prominent issues addressed by leadless pacemakers (LPM). These...
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Comparison of microscopic full-laminectomy (open surgery) and microendoscopic minimally invasive hemilaminectomy for thoracic extramedullary spinal tumours
BackgroundMinimally invasive treatments for spinal cord tumours are common. The aim of this study was to compare the perioperative outcomes of...
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Application of a Novel Mitral Valvuloplasty Strategy in Children with Mitral Regurgitation
To retrospectively analyze the clinical efficacy of an innovative mitral valvuloplasty strategy in the treatment of mitral regurgitation in children....
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Prevalence and risk factors of deep venous thrombosis of hospitalizations in plateau: a cross-section analysis
BackgroundDeep venous thrombosis (DVT) is a serious public health issue that threatens human health and economic development. Presently, differences...
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Breathing difficulties in a nonagenarian: a self report
This is a self report. It is age related because I am 96 years old; about 5 years ago I was asymptomatic in this respect. I describe the difficulties...
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Ablation apprentices and their first experience of pulmonary vein isolation procedure on paroxysmal atrial fibrillation with different sheaths
ObjectivesThis study aimed at exploring how using different kinds of sheaths will affect the very first ablation procedure of apprentices.
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Anomalous right coronary artery managed with bypass and proximal ligation
BackgroundAn anomalous origin and inter-arterial course of the right coronary artery is a rare anomaly that can lead to sudden ischemic cardiac death...
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Next-generation atrial fibrillation ablation: clinical performance of pulsed-field ablation and very high-power short-duration radiofrequency
IntroductionPulsed-field energy (PFA) and very high-power short-duration radiofrequency (vHPSD-RF) are two novel ablation methods for pulmonary vein...
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Lecithin and cardiovascular health: a comprehensive review
BackgroundCardiovascular diseases are one of the prime causes of mortality globally. Therefore, concerted efforts are made to prevent or manage...
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Uric acid to albumin ratio as a novel predictor for coronary slow flow phenomenon in patients with chronic coronary syndrome and non-obstructive coronary arteries
BackgroundThe plasma uric acid to albumin ratio (UAR) is considered as a novel indicator for Inflammation. However, the association between UAR and...