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Functional and clinical roles of stromal PDGF receptors in tumor biology
PDGF receptors play pivotal roles in both developmental and physiological processes through the regulation of mesenchymal cells involved in paracrine...
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Dual targeting non-overlap** epitopes in HER2 domain IV substantially enhanced HER2/HER2 homodimers and HER2/EGFR heterodimers internalization leading to potent antitumor activity in HER2-positive human gastric cancer
BackgroundTrastuzumab and pertuzumab combination has been approved for the treatment of patients with HER2-positive metastatic breast cancer....
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KIAA1429 promotes the malignancy of oral squamous cell carcinoma by regulating CA9 m6A methylation
KIAA1429 has been reported as a cancer regulator, but its role and mechanism in the progression of oral squamous cell carcinoma (OSCC) remain...
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Extremal Properties of Random Structures
The extremal characteristics of random structures, including trees, graphs, and networks, are discussed. A statistical physics approach is employed...
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On the Analysis of Backtrack Proceduresfor the Colouring of Random Graphs
Backtrack search algorithms are procedures capable of deciding whether a decision problem has a solution or not through a sequence of trials and...
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Attacks and Cascades in Complex Networks
This paper reviews two problems in the security of complex networks: cascades of overload failures on nodes and range-based attacks on links....
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Tomography and Stability of Complex Networks
We study the structure of generalized random graphs with a given degree distribution P(k), and review studies on their behavior under both random...
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Topology, Hierarchy, and Correlations in Internet Graphs
We present a statistical analysis of different metrics characterizing the topological properties of Internet maps, collected at two different...
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The Small World Phenomenonin Hybrid Power Law Graphs
The small world phenomenon, that consistently occurs in numerous existing networks, refers to two similar but different properties — small average...
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Critical Phenomena in a Small World
We consider the behavior of various systems on a small-world network near a critical point. Our starting point is a different, nonrandom system with...
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Who Is the Best Connected Scientist?A Study of Scientific Coauthorship Networks
Using data from computer databases of scientific papers in physics, biomedical research, and computer science, we have constructed networks of...
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Scholarly Information Network
I review the background and some recent trends of a particular scholarly information network, ar**v.org, and discuss some of its implications for new...
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Spectral Analysis of Random Networks
We review a general approach that describes the spectra of eigenvalues for random graphs with a local tree-like structure. The exact equations to the...
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Theoretical Neuroanatomy:Analyzing the Structure, Dynamics,and Function of Neuronal Networks
The mammalian brain is an extraordinary object: its networks give rise to our conscious experiences as well as to the generation of adaptive behavior...
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Information Theory of Complex Networks: On Evolution and Architectural Constraints
Complex networks are characterized by highly heterogeneous distributions of links, often pervading the presence of key properties such as robustness...
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Course 14: Hiking through Glassy Phases: Physics beyond Aging
Experiments performed on a wide range of glassy materials display many interesting phenomena, such as aging behavior. In recent years, a large body...
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Course 6: Glasses, Replicas and All That
In these lectures I will review the approach to glasses based on the replica formalism. Many of the physical ideas are very similar to those of older...
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Regulation of IP 3 Receptors by IP 3 and Ca 2+
Inositol 1,4,5-trisphosphate ( IP 3) receptors are intracellular Ca 2+ channels that mediate release of Ca 2+ from intracellular stores. The channels...
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Modeling Calcium Waves
We present an introduction to the mathematics of calcium waves, both intracellular and intercellular. After a discussion of the earlier models I...
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Hormone-Mediated Intercellular Calcium Signalling in an Insect Salivary Gland – Pathways and Mechanisms
The salivary glands of the blowfly Calliphora vicina are a favourable preparation for investigations into spatio-temporal Ca 2+ dynamics in an intact...