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Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action?
Neurodegenerative diseases and brain tumours represent important health challenges due to their severe nature and debilitating consequences that...
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Therapeutic potential of transient receptor potential (TRP) channels in psychiatric disorders
Psychiatric disorders such as Bipolar disorder, Anxiety, Major depressive disorder, Schizophrenia, Attention-deficit/hyperactivity disorder, as well...
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FABP3 Induces Mitochondrial Autophagy to Promote Neuronal Cell Apoptosis in Brain Ischemia-Reperfusion Injury
This study elucidates the molecular mechanisms by which FABP3 regulates neuronal apoptosis via mitochondrial autophagy in the context of cerebral...
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Stability of N-type inactivation and the coupling between N-type and C-type inactivation in the Aplysia Kv1 channel
The voltage-dependent potassium channels (Kv channels) show several different types of inactivation. N-type inactivation is a fast inactivating...
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A Short Game-Based Intervention for Enhancing Executive Functions at School: a Pilot Study
Executive functions (EFs) are crucial for self-regulation, and they can explain the difficulties that many children face at school in terms of both...
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Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
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Gras** the big picture: impact analysis of screening tools for timely referral for device-aided therapies
Several screening tools are available to assist general neurologists in the timely identification of patients with advanced Parkinson’s disease (PD)...
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Stroke heart injury: the effect of cerebral reperfusion treatment. A 3-year retrospective study
BackgroundCardiac involvement following an acute stroke (Stroke Heart Syndrome—SHS) is an established complication and it is linked to the...
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Estimating the Trial-by-Trial Learning Curve in Perceptual Learning with Hierarchical Bayesian Modeling
The learning curve serves as a crucial metric for assessing human performance in perceptual learning. It may encompass various component processes,...
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Multivariate associations between neuroanatomy and cognition in unmedicated and medicated individuals with schizophrenia
Previous studies that focused on univariate correlations between neuroanatomy and cognition in schizophrenia identified some inconsistent findings....
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Prevalence and correlates of common mental disorders among participants of the Uganda Genome Resource: Opportunities for psychiatric genetics research
Genetics research has potential to alleviate the burden of mental disorders in low- and middle-income-countries through identification of new...
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PET imaging of neuroinflammation: any credible alternatives to TSPO yet?
Over the last decades, the role of neuroinflammation in neuropsychiatric conditions has attracted an exponentially growing interest. A key driver for...
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What to Measure in Aneurysmal Subarachnoid Haemorrhage Research—An International Delphi Survey
Aneurysmal subarachnoid haemorrhage (aSAH) is a devastating condition with high mortality and morbidity. The outcome measures used in aSAH clinical...
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The effects of empagliflozin on ventricular arrhythmias in heart failure patients with an implantable cardioverter-defibrillator: a double-blind randomized controlled trial
Sodium-glucose transporter 2 (SGLT2) inhibitors such as empagliflozin are one of the main treatments for type 2 diabetes mellitus (DM2) and heart...
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Inter-joint coordination with and without dopaminergic medication in Parkinson’s disease: a case-control study
BackgroundHow the joints exactly move and interact and how this reflects PD-related gait abnormalities and the response to dopaminergic treatment is...
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Intelligent ankle–foot prosthesis based on human structure and motion bionics
The ankle–foot prosthesis aims to compensate for the missing motor functions by fitting the motion characteristics of the human ankle, which...
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