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Inhibitors of apolipoprotein C3, triglyceride levels, and risk of pancreatitis: a systematic review and meta-analysis
In recent years, novel apoC3 inhibitor therapies for the treatment of hypertriglyceridemia have been developed and assessed through phase II and III...
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DNA Methylation-derived biological age and long-term mortality risk in subjects with type 2 diabetes
BackgroundIndividuals with type 2 diabetes (T2D) face an increased mortality risk, not fully captured by canonical risk factors. Biological age...
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Breathing difficulties in a nonagenarian: a self report
This is a self report. It is age related because I am 96 years old; about 5 years ago I was asymptomatic in this respect. I describe the difficulties...
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Healthcare costs and medical utilization patterns associated with painful and severe painful diabetic peripheral neuropathy
PurposePainful diabetic peripheral neuropathy (DPN) is a common complication in patients with diabetes. It is associated with a poor quality of life...
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Comprehensive analysis of the association between triglyceride-glucose index and coronary artery disease severity across different glucose metabolism states: a large-scale cross-sectional study from an Asian cohort
BackgroundThe triglyceride-glucose (TyG) index is associated with the development and prognosis of coronary artery disease (CAD). However, the impact...
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Influence of prediabetes on the prognosis of patients with myocardial infarction: a meta-analysis
BackgroundPrevious studies evaluating the association between prediabetes the prognosis of patients with acute myocardial infarction (AMI) showed...
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Does metformin really reduce prostate cancer risk: an up-to-date comprehensive genome-wide analysis
BackgroundThe relationship between metformin use and prostate cancer (PCa) risk has yet to be clear despite more than a decade of debate on this...
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Nourishing Physical Productivity and Performance On a Warming Planet - Challenges and Nutritional Strategies to Mitigate Exertional Heat Stress
Purpose of ReviewClimate change is predicted to increase the frequency and severity of exposure to hot environments. This can impair health, physical...
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Screening for diabetic retinopathy with artificial intelligence: a real world evaluation
AimPeriodic screening for diabetic retinopathy (DR) is effective for preventing blindness. Artificial intelligence (AI) systems could be useful for...
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Efficacy and Safety of Atogepant for Preventing Chronic and Episodic Migraines: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Purpose of ReviewCalcitonin gene-related peptide (CGRP) pathway modulators, such as atogepant, represent a novel therapeutic option for the treatment...
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CTX-1 and TRACP-5b as biomarkers for osteoporosis risk in type 2 diabetes mellitus: a cross-sectional study
ObjectiveType 2 diabetes mellitus (T2DM) demonstrates a higher risk of fractures compared to the healthy population. Therefore, the aim of our study...
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Healthy lifestyle index development and its association with type 2 diabetes mellitus status among teachers
BackgroundType 2 diabetes mellitus (T2DM) is a significant health concern and imposes a substantial burden on society. Although leading a healthy...
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The relationship between follicle-stimulating hormone and metabolic dysfunction-associated fatty liver disease in men
ObjectivesThe present study aimed to investigate the relationship between male hormones and metabolic dysfunction-associated fatty liver disease...
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Mechanical Thrombectomy for Acute Ischemic Stroke: Current State and Future Directions
Purpose of reviewThis review summarizes significant advancements in mechanical thrombectomy (MT) to treat acute ischemic stroke after the pivotal...
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miPEP31 alleviates Ang II-induced hypertension in mice by occupying Cebpα binding sites in the pri-miR-31 promoter
BackgroundPrevious studies have shown that peptides encoded by noncoding RNAs (ncRNAs) can be used as peptide drugs to alleviate diseases. We found...
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Self-care practice and associated factors among patients with diabetes on follow-up at Yirgalem General Hospital, Sidama, Ethiopia: a cross-sectional study
BackgroundSelf-care practice is an integral and efficient part of comprehensive diabetes management, which could be influenced by various...
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A consensus statement from the Japan Diabetes Society (JDS): a proposed algorithm for pharmacotherapy in people with type 2 diabetes—2nd Edition (English version)
The Japan Diabetes Society (JDS) adopted a swee** decision to release consensus statements on relevant issues in diabetes management that require...