Search
Search Results
-
The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice
BackgroundThis study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk...
-
Contribution of plasma levels of VEGF-A and angiopoietin-2 in addition to a genetic variant in KCNAB1 to predict the risk of bevacizumab-induced hypertension
Bevacizumab-induced hypertension poses a therapeutic challenge and identifying biomarkers for hypertension can enhance therapy safety. Lower plasma...
-
Presence of Fusobacterium nucleatum in relation to patient survival and an acidic environment in oesophagogastric junction and gastric cancers
BackgroundFusobacterium nucleatum inhabits the oral cavity and affects the progression of gastrointestinal cancer. Our prior findings link F....
-
A genetic variant in the TAPBP gene enhances cervical cancer susceptibility by increasing m6A modification
Genetic variants can affect gene expression by altering the level of N6-methyladenosine (m 6 A) modifications. A better understanding of the...
-
Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study
BackgroundMost gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has...
-
Machine learning to optimize literature screening in medical guideline development
ObjectivesIn a time of exponential growth of new evidence supporting clinical decision-making, combined with a labor-intensive process of selecting...
-
Digital biomarkers for non-motor symptoms in Parkinson’s disease: the state of the art
Digital biomarkers that remotely monitor symptoms have the potential to revolutionize outcome assessments in future disease-modifying trials in...
-
Fasting in combination with the cocktail Sorafenib:Metformin blunts cellular plasticity and promotes liver cancer cell death via poly-metabolic exhaustion
PurposeDual-Interventions targeting glucose and oxidative metabolism are receiving increasing attention in cancer therapy. Sorafenib (S) and...
-
Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care
Background and objectivesClinical data are essential for develo** cloud platforms for intelligent diagnosis and treatment decision of diseases....
-
From bench to bedside: the application of cannabidiol in glioma
Glioma is the most common malignant tumor in central nervous system, with significant health burdens to patients. Due to the intrinsic...
-
Snn and sound: a comprehensive review of spiking neural networks in sound
The rapid advancement of AI and machine learning has significantly enhanced sound and acoustic recognition technologies, moving beyond traditional...
-
A Review on Small Molecule Based Fluorescence Chemosensors for Bioimaging Applications
This review provides a thorough examination of small molecule-based fluorescence chemosensors tailored for bioimaging applications, showcasing their...
-
A new approach to prevent radiation-induced xerostomia using intraglandular injection of mitochondria-boosting agents
Radiotherapy in patients with head and neck cancer fairly leads to xerostomia, profoundly affecting their quality of life. With limited effective...
-
The ANGPTL4-HIF-1α loop: a critical regulator of renal interstitial fibrosis
BackgroundRenal interstitial fibrosis (RIF) is a progressive, irreversible terminal kidney disease with a poor prognosis and high mortality....
-
Dual inhibition of SUMOylation and MEK conquers MYC-expressing KRAS-mutant cancers by accumulating DNA damage
BackgroundKRAS mutations frequently occur in cancers, particularly pancreatic ductal adenocarcinoma, colorectal cancer, and non-small cell lung...
-
Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results
Adoptive cell transfer (ACT) with neoantigen-reactive T lymphocytes can mediate cancer regression. Here we isolated unique, personalized,...
-
Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition
Current cardiometabolic disease prevention guidelines recommend increasing dietary unsaturated fat intake while reducing saturated fats. Here we use...
-
Benmelstobart, anlotinib and chemotherapy in extensive-stage small-cell lung cancer: a randomized phase 3 trial
Immunochemotherapy is the first-line standard for extensive-stage small-cell lung cancer (ES-SCLC). Combining the regimen with anti-angiogenesis may...
