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Multimodal training protocols on unstable rather than stable surfaces better improve dynamic balance ability in older adults
BackgroundThere has been growing interest in using unstable devices in training protocols. This study aimed to assess the effectiveness of two...
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Nuclear alpha-synuclein accelerates cell senescence and neurodegeneration
BackgroundThe progression of Parkinson’s disease (PD) is related to ageing. The accumulation of nuclear alpha-synuclein (α-syn) may accelerate the...
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Relationship between quantitative physical activity and deterioration of locomotive function: a cross-sectional study using baseline data from a cohort
BackgroundIn aged society, health policies aimed at extending healthy life expectancy are critical. Maintaining physical activity is essential to...
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Differences of anticholinergic drug burden between older hospitalized patients with and without delirium: a systematic review and meta-analysis based on prospective cohort studies
ObjectivesThis review aims to comprehensively summarize the differences in anticholinergic drug burden (ADB) scores between older hospitalized...
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Childhood intra- and extra-familial maltreatment and later-life trajectories of depressive symptoms: evidence from China
BackgroundBoth late-life depression and childhood maltreatment have become major global public health issues, given their prevalence and...
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What determines informal care need among community-dwelling older adults in China? Results from a longitudinal study
BackgroundWith an intensified aging population and an associated upsurge of informal care need in China, there is an ongoing discussion around what...
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Enhancing the Utility of the Moral Injury Experience Wheel: Manualized Applications for Diverse Contexts
Moral injury has emerged as an important construct for understanding the distress experienced in the aftermath of a moral violation, initially among...
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Association between antidepressant use and delirium in older adults: an analysis of the World Health Organization’s global pharmacovigilance database
BackgroundPsychoactive drugs frequently cause delirium adverse events in older adults. However, few data on the relationship between antidepressants...
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Association between sleep duration and possible sarcopenia in middle-aged and elderly Chinese individuals: evidence from the China health and retirement longitudinal study
BackgroundSarcopenia is a common cause of disability in the aging population, and managing sarcopenia is an important step in building intrinsic...
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Atypical chronic myeloid leukemia found in a patient with eosinophilia for six years: a case report
BackgroundAtypical chronic myeloid leukemia (aCML) is a highly aggressive type of blood cancer that falls under the category of...
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Acceptability and preliminary effects of the volunteer-supported Meaningful Moments program to engage older adults with advanced dementia on a hospital-based specialized dementia care unit: a mixed methods study
BackgroundNamaste Care offers practical skills for healthcare providers, volunteers, and families to meaningfully engage individuals with dementia in...
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Self-perceptions of aging, physical activity, and depressive symptoms in older community residents with varied neighborhood walkability in Taiwan
BackgroundPrior research has identified the mediating effect of physical activity in the relationship between self-perceptions of aging and physical...
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Examining Audiences’ Psychological Reactance to Christian-Sourced Excessive Alcohol Consumption Messages in the United States
This study experimentally investigated the effect of dogmatic and suggestive language in Christian-sourced excessive alcohol consumption messages...
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The impact of discharge letter content on unplanned hospital readmissions within 30 and 90 days in older adults with chronic illness – a mixed methods study
BackgroundCare transitions are high-risk processes, especially for people with complex or chronic illness. Discharge letters are an opportunity to...
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“Multidisciplinary fast-track” care can significantly reduce risk of mortality among hip fracture patients at least 80 years old: a single-center retrospective study
Background“Multidisciplinary fast-track” (MFT) care can accelerate recovery and improve prognosis after surgery, but whether it is effective in older...
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Strategies for modeling aging and age-related diseases
The ability to reprogram patient-derived-somatic cells to IPSCs (Induced Pluripotent Stem Cells) has led to a better understanding of aging and...
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Psychosocial and biological pathways to aging
While the biological hallmarks of aging are widely recognized as fundamental mechanisms of biological aging, more recently, there have been calls...
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Community-based exercises improve health status in pre-frail older adults: A systematic review with meta-analysis
BackgroundPre-frailty is associated with increased healthcare utilization. Over the past decade, public health interventions such as community-based...
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Step** towards health: a sco** review of square-step** exercise protocols and outcomes in older adults
BackgroundSquare-Step** Exercise (SSE) is a type of physical-cognitive exercise. Such exercise has been used as an exercise approach in different...
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Applying Kumpfer’s resilience framework to understand the social adaptation process of the trailing parents in China
BackgroundTrailing parents, a distinct group emerging from China’s rapid social change and urbanization, are experiencing migration in old age,...
