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Clinical significance of circulating biomarkers of immune-checkpoint molecules with atezolizumab plus bevacizumab therapy in unresectable hepatocellular carcinoma
BackgroundThe aims of this study were to identify clinically significant biomarkers of a response to atezolizumab plus bevacizumab (ATZ + BV) therapy...
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Benefits of Hepatitis C Viral Eradication: A Real-World Nationwide Cohort Study in Taiwan
BackgroundChronic hepatitis C (CHC) increases the risk of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). This nationwide cohort study...
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Transoral endoscopic thyroidectomy submental vestibular approach for early-stage papillary thyroid carcinoma: a systematic review and meta-analysis
PurposeOur study aimed to compare the effectiveness and complications of the transoral endoscopic thyroidectomy submental vestibular approach...
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Antibody–drug conjugates in gastric cancer: from molecular landscape to clinical strategies
Antibody–drug conjugates (ADCs) represent a crucial component of targeted therapies in gastric cancer, potentially altering traditional treatment...
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As the Worm Turns—A Rare Cause of Intestinal Obstruction
BackgroundAnisakiasis, a zoonotic disease caused by the nematode Anisakis , poses a significant concern for public health, particularly in regions...
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Insights into the current state of knowledge, practice, and attitudes of physicians regarding gastrointestinal motility disorders in Egypt
BackgroundGastrointestinal (GI) motility disorders are common in clinical settings, but physicians still lack sufficient understanding and effective...
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DAMP-ing IBD: Extinguish the Fire and Prevent Smoldering
In inflammatory bowel diseases (IBD), the most promising therapies targeting cytokines or immune cell trafficking demonstrate around 40% efficacy. As...
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Clinical Characteristics and Prognosis of Early-Onset Hepatocellular Carcinoma: A Retrospective Cohort Study Based on Population Data
BackgroundThe incidence of young patients diagnosed with hepatocellular carcinoma (HCC) is projected to rise. This study aimed to investigate the...
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Excisional biopsy of perforated gastric ulcer: mandatory or potentially harmful?
PurposeThis study aimed to evaluate the morbidity associated with excisional biopsy in patients with spontaneous gastric perforation.
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Factors Associated with Delays in Initiating Biologic Therapy in Patients with Inflammatory Bowel Disease
IntroductionExpeditious initiation of biologic therapy is important in patients with inflammatory bowel disease (IBD). However, initiation of...
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Incidence and risk factors for perineal hernia after robotic abdominoperineal resection: a single-center, retrospective cohort study
BackgroundPerineal hernia (PH) is a late complication of abdominoperineal resection (APR) that may compromise a patient’s quality of life. The...
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Deep learning-based image quality assessment: impact on detection accuracy of prostate cancer extraprostatic extension on MRI
ObjectiveTo assess impact of image quality on prostate cancer extraprostatic extension (EPE) detection on MRI using a deep learning-based AI...
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Prognostic scores for predicting clinical outcomes in upper gastrointestinal bleeding
Background and aimsThis study aimed to determine the performance of AIMS65, Rockall score, and Glasgow-Blatchford score (GBS) in patients presenting...
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Surgical Cholecystectomy Score (SCS) for grading the difficulty of laparoscopic cholecystectomy
BackgroundLaparoscopic cholecystectomy (LC) is the standard of care for symptomatic gall stone disease. A good scoring system is necessary to...
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Hepatic arterial infusion chemotherapy plus camrelizumab and apatinib for advanced hepatocellular carcinoma
Background and aimsThere is limited information on combination of hepatic arterial infusion chemotherapy (HAIC) and systemic therapy for advanced...
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Artificial intelligence automated surgical phases recognition in intraoperative videos of laparoscopic pancreatoduodenectomy
BackgroundLaparoscopic pancreatoduodenectomy (LPD) is one of the most challenging operations and has a long learning curve. Artificial intelligence...
