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Article
Open AccessFunctionalized gold nanorods turn-on chemosensor for selective detection of Cd2+ ions, bio-imaging, and antineoplastic evaluations
A colorimetric turn-on chemosensor based on gold nanorods, Au NRs, has been developed to enable rapid, facile, and simultaneous detection of hazardous metal ions. This study involved the functionalization of g...
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Article
Open AccessNovel synthesis of γ-Al2O3/carbon hollow nanosphere nanocomposite for the optimal removal of Ni2+ ions from wastewater and reuse in blood fingerprint enhancement
This study aimed to solve environmental problems, particularly water quality and escalating crime rates. The carbon hollow nanosphere was prepared from orange peels by a reflux method. The carbon hollow nanosp...
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Article
Open AccessSynthesis and Antioxidant Activity of Some Benzoquinoline-Based Heterocycles Derived from 2-((3-Chlorobenzo[f]quinolin-2-yl)methylene)hydrazine-1-carbothioamide
A new series of benzoquinoline-based heterocycles was synthesized utilizing the building block synthon, 2-((3-chlorobenzo[f]quinolin-2-yl)methylene)hydrazine-1-carbothioamide via the condensation of 3-chlorobenzo...
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Article
Open AccessPyrazole-vaniline Schiff base disperse azo dyes for UV protective clothing: synthesis, characterization, comparative study of UPF, dyeing properties and potent antimicrobial activity
From 5-amino pyrazole, azo disperse pyrazole dyes containing o-vanillin have been synthesized and characterized using elemental analyses and Spectroscopic techniques. All synthesized dyes have been effectively us...
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Article
Open AccessAnti-carcinoma and anti -microbial behavioral studies for octahedral synthesized Schiff base metal complexes
2,2′-((1Z-1′Z) (1,3-diphenylpropane-1,3-diylidene) bis (azanylylidene)) dibenzoic acid (H2L) Schiff base ligand, derived from condensation reaction in a molar ratio 2:1 between anthranilic acid and dibenzoyl meth...
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Article
Open AccessRemoval of crystal violet dye from wastewater using low-cost biosorbent Trifolium repens stem powder
Crystal violet (CV) synthetic dyes are well known in the dyeing industry for their mitotic and mutagenic poisoning. CV dye being a toxic organic dye is responsible for serious health issues as well as environm...
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Article
Open AccessSynthesis of a novel chloroquinoline, rhodanine encompassed 1,2,3-triazole scaffolds and molecular docking evaluation of their cytotoxicity
A novel series of quinoline-linked rhodanine bearing 1,2,3-triazole analogs (10a-l) have been designed and prepared. All the novel hybrids were analyzed and characterized by spectroscopic performances like 1H-NMR...
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Article
Open AccessRegioselective three-component synthesis and theoretical calculations of new alkane-linked bis(thiazol-2(3H)-imine) hybrids: a DFT-based FMO and local reactivity indices
A three-component approach was conducted to adeptly prepare a new series of (Z)-bis(N-phenylthiazol-2(3H)-imines. The newly synthesized compounds were prepared by refluxing a ternary mixture of phenyl isothiocyan...
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Article
Open AccessValidated and selective potentiometric analysis of anti-coagulant edoxaban via a screen-printed electrode: green assessment by Eco-Scale and Complex-GAPI
Thromboembolism because of coronavirus infection (COVID-19) resulted in increasing the number of sudden deaths after recovery. So, patients were switched to edoxaban tosylate monohydrate (EDTM) therapy after l...
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Article
Open AccessSynthesis and antioxidant, antimicrobial, and antiviral activity of some pyrazole-based heterocycles using a 2(3H)-furanone derivative
Some pyrazole-based heterocycles such as pyrrolone, pyridazinone, and imidazole derivatives were synthesized utilizing the pyrazolyl-2(3H)-furanone derivative 3, which was obtained in a good yield via Perkin cond...
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Article
Open AccessDiscovery of novel anticancer candidates based on a combination strategy of synthesis, characterization, biological activity evaluation, consensus docking and molecular modeling
Through the Kabachnic-Fields three-component reaction of 3(2-amino-acetyl)-quinazolin-4(3H)-one, compound III, various aromatic aldehydes, triphenyl phosphite, and lithium perchlorate as Lewis acid catalyst, n...
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Article
Open AccessMTHPP monoacetic ester: unexpected formation, zinc metalation, thermal and photophysical properties
In the current investigation we report an unexpected methyl esterification occurred during the coupling reaction of mTHPP monoacetic acid 2 with 3-amino-1,2,4-triazole in the presence of HBTU/DIPEA. The mechanism...
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Article
Open AccessVoltammetric quantitative analysis of vildagliptin in bulk form and spiked human serum at a modified electrode
The electrochemical behavior of Vildagliptin (VILD) was studied using the cyclic voltammetric technique in an aqueous Britton–Robinson (BR) universal buffer solution of various pH levels between 4.0 and 10 at ...
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Article
Open AccessA new screen-printed electrode for selective determination of bismuth in different authentic samples
A new potentiometric method based on the screen-printed ion-selective electrode (SPISE) was described for the determination of Bi(III) ion in different authentic samples. The novelty is based on, for the first...
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Article
Open AccessApplication of nickel-doped graphene nanotubes to modified GCE as a sensitive electrochemical sensor for the antipsychotic drug clozapine in spiked human blood serum samples
Clozapine (CLZ) is one of the most vital medications for managing schizophrenia, and the timely measurement of CLZ levels has been recognized as an obstacle to the wider use of CLZ. Herein, for the first time,...
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Article
Open AccessGreen validated chromatographic methods for simultaneous determination of co-formulated oxytetracycline HCl and flunixin meglumine in the presence of their impurities in different matrices
Green analytical chemistry is an important area of chemical sciences. So, develo** competent eco-friendly analytical tools is a big challenge. This study devotes two chromatographic techniques for the simult...
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Article
Open AccessMicroextraction procedures for preconcentration of Fe (III) in water and food samples prior to colorimetric detection: a comparative study
Two extraction procedures, namely dispersive liquid-liquid microextraction (DLLME) and dispersive liquid-liquid microextraction based on solidification of floating organic drop (DLLME-SFOD), have been compared...
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Article
Open AccessDesign, synthesis, and biological investigation of quinoline/ciprofloxacin hybrids as antimicrobial and anti-proliferative agents
Ciprofloxacin-Piperazine C-7 linked quinoline derivatives 6a–c and 8a–c were synthesized and investigated for their antibacterial, antifungal, and anti-proliferative activities. Ciprofloxacin-quinoline-4-yl-1,3,4...
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Article
Open AccessDirect analysis of thorium(IV) ions concentration in water samples using a new carbon paste electrode
The radioactive and hazardous nature of thorium demands the fabrication of efficient electrodes for its sensitive and selective monitoring in aqueous environments. The present paper reports the construction an...
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Article
Open AccessBoosting the antimicrobial performance based on new fused spirothiazolidine framework analogs
New spiro[cyclohexane-1,2'-thiazolo[4,5-b]pyridine derivatives (3–23) were investigated. Then there is in vitro antimicrobial potency against possible organisms Staphylococcus aurous ATCC-47,077, Bacillus cereus ...
