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Neurological Sciences

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Neurological Sciences

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  1. Article

    Open Access

    Optimized trans-cranial direct current stimulation for prolonged consciousness disorder in a patient with titanium mesh cranioplasty

    Transcranial direct current stimulation (tDCS) has been used for the restoration of awareness in patients with a minimal consciousness state (MCS). Most brains of patients in MCS may structurally and electroph...

    Sun Im, Geun-Young Park, Tae-Woo Kim, Seong Hoon Lim in Neurological Sciences (2024)

  2. Article

    Open Access

    Cost and effectiveness of autologous haematopoietic stem cell transplantation and high-efficacy disease-modifying therapies in relapsing–remitting multiple sclerosis

    Autologous haematopoietic stem cell transplantation (AHSCT) is a highly effective one-off treatment for relapsing–remitting multiple sclerosis (RR-MS), potentially representing an optimal front-loading strateg...

    Alice Mariottini, Chiara Nozzoli, Ilaria Carli, Filippo Landi in Neurological Sciences (2024)

  3. Article

    Open Access

    The effects of anastomoses between anterior and posterior circulation on postoperative prognosis of patients with moyamoya disease

    Moyamoya disease (MMD) is a chronic ischemic cerebrovascular disease. Collateral circulation in MMD has emerged as a research focus. Our aims were to assess the impact of anastomoses between the anterior and p...

    Yuan Yuan, Xuchao He, Yin Li, Lingji **, Yuhan Zhu, Gaojun Lin in Neurological Sciences (2024)

  4. Article

    Open Access

    The validation of a Japanese version of the New Freezing of Gait Questionnaire (NFOG-Q)

    This study aimed to develop a Japanese version of the New Freezing of Gait Questionnaire (NFOG-Q) and investigate its validity and reliability.

    Seira Taniguchi, Kohei Marumoto, Yuta Kajiyama, Gajanan Revankar in Neurological Sciences (2024)

  5. Article

    Open Access

    Safety of masitinib in patients with neurodegenerative diseases: a meta-analysis of randomized controlled trials

    This meta-analysis aimed to examine the safety of masitinib in patients with neurodegenerative diseases.

    Abdullah Ashraf Hamad, Basma Ehab Amer in Neurological Sciences (2024)

  6. Article

    Open Access

    Daridorexant treatment for chronic insomnia: a real-world retrospective single-center study

    Chronic insomnia disorder (CID) significantly impacts well-being and daily functioning. Daridorexant, a double orexin receptor blocker, has shown efficacy in randomized clinical trials and has been recently ap...

    Mariana Fernandes, Fabio Placidi, Nicola Biagio Mercuri in Neurological Sciences (2024)

  7. Article

    Open Access

    Monoclonal antibodies targeting the calcitonin gene-related peptide pathway improve the effectiveness of acute medication—a real-world study

    One of the aims of migraine prevention is to improve response to acute migraine treatments. The aim of the present study was to assess whether monoclonal antibodies targeting the CGRP pathway (CGRP-mAbs) can i...

    Chiara Rosignoli, Valeria Caponnetto, Agnese Onofri in Neurological Sciences (2024)

  8. Article

    Open Access

    Clinical characteristics and dynamics of disability progression in a cohort of patients with multiple sclerosis in Latvians

    There is wide variation in the time from the onset to secondary progressive multiple sclerosis (MS) and some controversy regarding the clinical characteristics of the courses (phenotypes) of MS. The present st...

    Jolanta Kalnina, Ilva Trapina, Nikolajs Sjakste in Neurological Sciences (2024)

  9. Article

    Open Access

    Post-sepsis psychiatric disorder: Pathophysiology, prevention, and treatment

    Post-sepsis psychiatric disorder, encompassing anxiety, depression, post-traumatic stress disorder and delirium, is a highly prevalent complication secondary to sepsis, resulting in a marked increase in long-t...

    Dayong Li, Xujie Zhang, Yuru Lu, Liang **g, Hongjie Hu in Neurological Sciences (2024)

  10. Article

    Open Access

    Identifying definite patterns of unmet needs in patients with multiple sclerosis using unsupervised machine learning

    People with multiple sclerosis (PwMS) exhibit a spectrum of needs that extend beyond solely disease-related determinants. Investigating unmet needs from the patient perspective may address daily difficulties a...

    Elisabetta Maida, Gianmarco Abbadessa, Eleonora Cocco in Neurological Sciences (2024)

  11. Article

    Open Access

    LSVT® BIG versus progressive structured mobility training through synchronous telerehabilitation in Parkinson’s disease: A randomized controlled trial

    Parkinson’s disease (PD) is a common neurodegenerative illness associated with motor symptoms.

    Guzin Kaya Aytutuldu, Burcu Ersoz Huseyinsinoglu in Neurological Sciences (2024)

  12. Article

    Open Access

    Magnetic resonance imaging scoring system of the lower limbs in adult patients with suspected idiopathic inflammatory myopathy

    We aim to propose a visual quantitative score for muscle edema in lower limb MRI to contribute to the diagnosis of idiopathic inflammatory myopathy (IIM).

    Laura Ludovica Gramegna, Rita Rinaldi in Neurological Sciences (2024)

  13. Article

    Open Access

    Comorbidity in myasthenia gravis: multicentric, hospital-based, and controlled study of 178 Italian patients

    Myasthenia gravis (MG) is an autoimmune disorder with fluctuating weakness that causes significant disability and morbidity. Comorbidities may influence the course of MG, particularly in specific subgroups. Th...

    Vincenzo Di Stefano, Salvatore Iacono, Massimiliano Militello in Neurological Sciences (2024)

  14. Article

    Open Access

    Validation of the Italian version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease-Rating Scale (QUIP-RS) in an Italian Parkinson’s disease cohort

    Impulse control disorders (ICDs) frequently occur in Parkinson’s disease (PD), and an early identification is essential to prevent severe psychosocial consequences. The Questionnaire for Impulsive-Compulsive D...

    Gianpaolo Maggi, Carmine Vitale, Chiara Giacobbe, Angelo Barone in Neurological Sciences (2024)

  15. Article

    Open Access

    Language impairments in seropositive and seronegative autoimmune encephalitis

    Autoimmune encephalitis (AE) is a rare neuroinflammatory disease affecting the central nervous system. To examine language functions in patients with different subsets of AE consisting of seropositive and sero...

    Sarah P. Griffith, Robb Wesselingh, Fiore D’Aprano, Nabil Seery in Neurological Sciences (2024)

  16. Article

    Open Access

    Intervention modalities for brain fog caused by long-COVID: systematic review of the literature

    Individuals suffering from long-COVID can present with “brain fog”, which is characterized by a range of cognitive impairments, such as confusion, short-term memory loss, and difficulty concentrating. To date,...

    Alon Gorenshtein, Tom Liba, Liron Leibovitch, Shai Stern in Neurological Sciences (2024)

  17. Article

    Open Access

    The Dubousset Functional Test: a reliable and valid test in early stage Parkinson’s disease patients

    Dubousset Functional Test (DFT) is an assessment test evaluating the functional capacity and dynamic balance. The study aimed to examine the reliability, validity, and responsiveness of the DFT in early stage ...

    Ayşe Abit Kocaman, Saniye Aydoğan Arslan, Yusuf Emre Bozkurt in Neurological Sciences (2024)

  18. Article

    Open Access

    Neurophysiological signatures of mild traumatic brain injury in the acute and subacute phase

    Mild traumatic brain injury (mTBI) affects 48 million people annually, with up to 30% experiencing long-term complaints such as fatigue, blurred vision, and poor concentration. Assessing neurophysiological fea...

    Valentina Barone, Myrthe E. de Koning, Harm J. van der Horn in Neurological Sciences (2024)

  19. Article

    Open Access

    Effects of home-based neurostimulation on outcomes after stroke: a systematic review and meta-analysis

    Home-based rehabilitation is a cost-effective means of making services available for patients. The aim of this study is to determine the evidence in the literature on the effects of home-based neurostimulation i...

    Auwal Abdullahi, Thomson W. L. Wong, Shamay S. M. Ng in Neurological Sciences (2024)

  20. Article

    Open Access

    Subcutaneous immunoglobulins (SCIG) for chronic inflammatory demyelinating polyneuropathy (CIDP): A comprehensive systematic review of clinical studies and meta-analysis

    Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) presents significant treatment challenges due to its chronic nature, varied clinical presentations, and rarity. Subcutaneous immunoglobulin (SCIG) has e...

    Ahmed Ramzi, Subhia Maya, Nadeen Balousha, Haneen Sabet in Neurological Sciences (2024)

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