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Clinical Rheumatology

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Clinical Rheumatology

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  1. Article

    Open Access

    Abdominal erythema ab igne—beyond the rash

    Roland van Rensburg, Helmuth Reuter in Clinical Rheumatology (2024)

  2. Article

    Open Access

    Dynamics of serum levels of TNF-α in a longitudinal follow-up study in 98 patients with juvenile idiopathic arthritis treated with anti-TNF-α biological drugs

    To determine the dynamics of serum levels of TNF-α in patients with juvenile idiopathic arthritis (JIA) treated with anti-TNF-α biological drugs and investigate their association with the disease activity.

    N. Morozova, M. Zajc Avramovič, G. Markelj, N. Toplak, T. Avčin in Clinical Rheumatology (2024)

  3. Article

    Open Access

    Cardiovascular disease risk assessment in patients with rheumatoid arthritis: A sco** review

    Patients with rheumatoid arthritis (RA) have an increased risk of develo** cardiovascular disease (CVD). Identification of at-risk patients is paramount to initiate preventive care and tailor treatments acco...

    Louise Murphy, Mohamad M. Saab, Nicola Cornally, Sheena McHugh in Clinical Rheumatology (2024)

  4. Article

    Open Access

    Unravelling relationships between obesity, diabetes, and factors related to somatosensory functioning in knee osteoarthritis patients

    This study explores the association between obesity, diabetes, and somatosensory functioning in patients with knee osteoarthritis (OA), aiming to understand how metabolic conditions are related to pain mechani...

    Lotte Meert, Sophie Vervullens, Christiaan H. W. Heusdens in Clinical Rheumatology (2024)

  5. Article

    Open Access

    Late-age onset systemic sclerosis—clinical and serological characteristics

    The clinical course and serological profile of the late-age onset systemic sclerosis (LAO SSc) and the early-age onset SSc (EAO SSc) was compared. The study enrolled 157 patients that fulfilled the American Co...

    Ewa Wielosz, Katarzyna Wiąk-Walerowicz, Ewa Łyś, Aleksandra Lipska in Clinical Rheumatology (2024)

  6. Article

    Open Access

    The circular RNA hsa_circ_0045800 serves as a favorable biomarker in pathogenesis of sjögren's syndrome

    Circular RNAs (circRNAs) play various roles in the development of many autoimmune diseases. However, their expression profiles and specific function in Sjögren's Syndrome remains largely unknown.

    Hong Zhu, Yi Wang, Ge Wang, Yitong Ling, **hai Tian, Yan Zhou in Clinical Rheumatology (2024)

  7. Article

    Open Access

    Estimation of optimal adherence threshold for tumor necrosis factor inhibitors in rheumatoid arthritis

    Optimal adherence thresholds can vary across medications and disease states. The objective of the study was to determine the optimal threshold of the proportion of days covered (PDC) for tumor necrosis factor ...

    Jennifer Toth Harris, Yi Yang, John P. Bentley, Yixin Chen in Clinical Rheumatology (2024)

  8. Article

    Open Access

    Durable control of psoriatic arthritis with guselkumab across domains and patient characteristics: post hoc analysis of a phase 3 study

    Evaluate patterns of stringent disease control with 2 years of guselkumab across key disease-identified domains and patient-reported outcomes (PROs) in subgroups of patients with psoriatic arthritis (PsA) defi...

    Christopher T. Ritchlin, Philip J. Mease, Wolf-Henning Boehncke in Clinical Rheumatology (2024)

  9. Article

    Open Access

    Optimising patient outcomes: temporal trends in remission rates of rheumatoid arthritis patients in the Australian OPAL dataset between 2009 and 2022

    To describe the trends in remission rates among RA patients in the OPAL dataset, spanning from 2009 to 2022, and provide insights into the effectiveness of evolving RA management approaches in real-world clini...

    Geoffrey Littlejohn, Nithila Anbumurali, Catherine O’Sullivan in Clinical Rheumatology (2024)

  10. Article

    Open Access

    Hematological indices in psoriatic enthesopathy: relation to clinical and ultrasound evaluation

    Enthesopathy is considered a crucial aspect of assessment and outcome in psoriatic arthritis (PsA). Musculoskeletal ultrasound (MSUS) is a critical tool for accurately detecting enthesitis. Recent research foc...

    Arwa S. Amer, Ahmed Y. Al Shambaky, Seham G. Ameen in Clinical Rheumatology (2024)

  11. Article

    Open Access

    Reduced T2*-weighted placental MRI predicts foetal growth restriction in women with chronic rheumatic disease—a Danish explorative study

    Women with chronic rheumatic disease (CRD) are at greater risk of foetal growth restriction than their healthy peers. T2*-weighted magnetic resonance imaging of placenta (T2*P-MRI) is superior to conventional ...

    Thea Vestergaard, Mette Julsgaard, Rikke Bek Helmig, Emilie Faunø in Clinical Rheumatology (2024)

  12. Article

    Open Access

    Does pain intensity after total knee arthroplasty depend on somatosensory functioning in knee osteoarthritis patients? A prospective cohort study

    The objective of this study is to determine whether the change in pain intensity over time differs between somatosensory functioning evolution profiles in knee osteoarthritis (KOA) patients undergoing total kn...

    Sophie Vervullens, Lotte Meert, Rob J. E. M. Smeets in Clinical Rheumatology (2024)

  13. Article

    Open Access

    An externally validated clinical-laboratory nomogram for myocardial involvement in adult idiopathic-inflammatory-myopathy patients

    This study aimed at identifying clinical and laboratory risk factors for myocardial involvement (MI) in idiopathic inflammatory myopathies (IIMs) patients as well as constructing a risk-predicted nomogram for ...

    Junyu Liang, Liyan Wan, Yake Yao, **ao Cui, Ye He, Shuangshuang Li in Clinical Rheumatology (2024)

  14. Article

    Open Access

    Metalloproteins as risk factors for osteoarthritis: improving and understanding causal estimates using Mendelian randomization

    Osteoarthritis (OA) is one of the most prevalent musculoskeletal disorders and a primary cause of pain and disability among the elderly population. Research on the relationship between metalloproteins (MPs) an...

    Jiaze Li, Mingyang Guan, Lin Qi, Feng** Zhang, Chenxu Jia in Clinical Rheumatology (2024)

  15. Article

    Open Access

    Opioid use surrounding diagnosis and follow-up in patients with ankylosing spondylitis, psoriatic arthritis, and rheumatoid arthritis: Results from US claims databases

    To describe patients’ use of opioids in the year preceding and year following new diagnosis of ankylosing spondylitis (AS), psoriatic arthritis (PsA), or rheumatoid arthritis (RA), compared with patients witho...

    Anna Sheahan, Suzanne Anjohrin, Robert Suruki, Jeffrey L. Stark in Clinical Rheumatology (2024)

  16. Article

    Open Access

    Association between enthesitis/dactylitis resolution and patient-reported outcomes in guselkumab-treated patients with psoriatic arthritis

    To evaluate the association between enthesitis resolution (ER) and dactylitis resolution (DR) and meaningful improvements in patient-reported outcomes (PROs) among biologic-naïve patients with PsA receiving gu...

    Proton Rahman, Iain B. McInnes, Atul Deodhar, Georg Schett in Clinical Rheumatology (2024)

  17. Article

    Open Access

    Prognostic modeling in early rheumatoid arthritis: reconsidering the predictive role of disease activity scores

    In this prospective cohort study, we provide several prognostic models to predict functional status as measured by the modified Health Assessment Questionnaire (mHAQ). The early adoption of the treat-to-target...

    Alix Bird, Lauren Oakden-Rayner, Luke A. Smith, Minyan Zeng in Clinical Rheumatology (2024)

  18. Article

    Open Access

    Increased carotid intima-media thickness in patients with radiographic axial spondyloarthritis compared to controls and associations with markers of inflammation

    There is an increased risk for cardiovascular disease (CVD) in patients with radiographic axial spondyloarthritis (r-axSpA). In this cross-sectional study, we aimed to, overall and stratified by sex, (i) compa...

    Lucy Law, Per Lindqvist, Per Liv, Urban Hellman, Kristina Lejon in Clinical Rheumatology (2024)

  19. Article

    Open Access

    Persistence on subcutaneous tocilizumab as monotherapy or in combination with synthetic disease-modifying anti-rheumatic drugs in rheumatoid arthritis patients in Greece (EMBRACE study): a multicenter, post-marketing, non-interventional, observational trial

    Rheumatoid arthritis (RA) is a systemic, inflammatory disease affecting multiple organs and causing physical disability over time.

    Panagiotis Athanassiou, Pelagia Katsimbri, Andreas Bounas in Clinical Rheumatology (2024)

  20. Article

    Open Access

    Real-world evaluation of persistence, effectiveness and usage patterns of tofacitinib in treatment of psoriatic arthritis in Australia

    To describe treatment patterns and persistence of tofacitinib, interleukin 17 inhibitors (IL-17Ai) and tumour necrosis factor inhibitors (TNFi), in patients with psoriatic arthritis (PsA).

    Geoffrey Littlejohn, Joanna Leadbetter, Belinda E. Butcher in Clinical Rheumatology (2024)

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