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Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function
CAR (CARSKNKDC) is a wound-homing peptide that recognises angiogenic neovessels. Here we discover that systemically administered CAR peptide has...
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Negative pressure wound therapy promotes wound healing of diabetic foot ulcers by up-regulating PRDX2 in wound margin tissue
To understand the changes in the peroxiredoxin-2 (PRDX2) expression level in the wound margin tissue (T-PRDX2) of patients with diabetic foot ulcer...
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Scarless wound healing programmed by core-shell microneedles
Effective reprogramming of chronic wound healing remains challenging due to the limited drug delivery efficacy hindered by physiological barriers, as...
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Quantifying innervation facilitated by deep learning in wound healing
The peripheral nerves (PNs) innervate the dermis and epidermis, and are suggested to play an important role in wound healing. Several methods to...
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Exosome-coated oxygen nanobubble-laden hydrogel augments intracellular delivery of exosomes for enhanced wound healing
Wound healing is an obvious clinical concern that can be hindered by inadequate angiogenesis, inflammation, and chronic hypoxia. While exosomes...
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Programmed microalgae-gel promotes chronic wound healing in diabetes
Chronic diabetic wounds are at lifelong risk of develo** diabetic foot ulcers owing to severe hypoxia, excessive reactive oxygen species (ROS), a...
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circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models
Chronic wounds are a major complication in patients with diabetes. Here, we identify a therapeutic circRNA and load it into small extracellular...
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Formulation and evaluation of simvastatin cubosomal nanoparticles for assessing its wound healing effect
Wound healing is one of the most challenging medical circumstances for patients. Pathogens can infect wounds, resulting in tissue damage,...
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Hydrogel dressings with intrinsic antibiofilm and antioxidative dual functionalities accelerate infected diabetic wound healing
Chronic wounds are often infected with biofilm bacteria and characterized by high oxidative stress. Current dressings that promote chronic wound...
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Adult skin fibroblast state change in murine wound healing
Wound healing is a well-organized dynamic process involving coordinated consecutive phases: homeostasis, inflammation, proliferation and resolution....
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LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing
Adipose stem cells (ASCs) have attracted considerable attention as potential therapeutic agents due to their ability to promote tissue regeneration....
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Photodynamic reactions using high-intensity red LED promotes gingival wound healing by ROS induction
Photodynamic therapy is a treatment that combines a light source with a photosensitizer. LEDs have attracted considerable attention in clinical...
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Dysregulated wound healing in the pathogenesis of urogynecologic mesh complications
To test the hypothesis that dysregulated wound healing is associated with Urogynecologic mesh complications, we collected vaginal cell secretions...
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In-situ-sprayed therapeutic hydrogel for oxygen-actuated Janus regulation of postsurgical tumor recurrence/metastasis and wound healing
Surgery is the mainstay of treatment modality for malignant melanoma. However, the deteriorative hypoxic microenvironment after surgery is recognized...
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Abnormal basement membrane results in increased keratinocyte-derived periostin expression in psoriasis similar to wound healing
The psoriatic skin resembles wound healing, and it shows abnormalities at the basement membrane (BM), also in the non-lesional skin....
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Wound healing and photoprotection properties of Acanthus ebracteatus Vahl. extracts standardized in verbascoside
Acanthus spp. have been documented in traditional Thai herbal medicine and are applicable for the treatment of inflamed skin with wound healing...
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HOXA3 accelerates wound healing in diabetic and aged non-diabetic mammals
Chronic wounds are characterized by a persistent, hyper-inflammatory environment that prevents progression to regenerative wound closure. Such...
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Unaltered hepatic wound healing response in male rats with ancestral liver injury
The possibility that ancestral environmental exposure could result in adaptive inherited effects in mammals has been long debated. Numerous rodent...
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Role of Hemigraphis alternata in wound healing: metabolomic profiling and molecular insights into mechanisms
Hemigraphis alternata ( H. alternata ), commonly known as Red Flame Ivy, is widely recognized for its wound healing capabilities. However, the...
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Assessment of wound healing activity in diabetic mice treated with a novel therapeutic combination of selenium nanoparticles and platelets rich plasma
Diabetic wound healing is sluggish, often ending in amputations. This study tested a novel, two-punch therapy in mice—Selenium nanoparticles (Se NPs)...
