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  1. Proteome allocation is linked to transcriptional regulation through a modularized transcriptome

    It has proved challenging to quantitatively relate the proteome to the transcriptome on a per-gene basis. Recent advances in data analytics have...

    Arjun Patel, Dominic McGrosso, ... Bernhard O. Palsson in Nature Communications
    Article Open access 19 June 2024
  2. Isoform-resolved transcriptome of the human preimplantation embryo

    Human preimplantation development involves extensive remodeling of RNA expression and splicing. However, its transcriptome has been compiled using...

    Denis Torre, Nancy J. Francoeur, ... Robert Sebra in Nature Communications
    Article Open access 30 October 2023
  3. High-resolution transcriptome datasets during embryogenesis of plant-parasitic nematodes

    Understanding the transcriptional regulatory characteristics throughout the embryogenesis of plant-parasitic nematodes is crucial for elucidating...

    Xueyu Wang, Zhiqing Guo, ... Donghai Peng in Scientific Data
    Article Open access 26 June 2024
  4. Transcriptome sequencing of seven deep marine invertebrates

    We present 4k video and whole transcriptome data for seven deep-sea invertebrate animals collected in the Eastern Pacific Ocean during a research...

    John A. Burns, Joost Daniels, ... David F. Gruber in Scientific Data
    Article Open access 24 June 2024
  5. Entire expressed peripheral blood transcriptome in pediatric severe malarial anemia

    This study on severe malarial anemia (SMA: Hb < 6.0 g/dL), a leading global cause of childhood morbidity and mortality, compares the entire expressed...

    Samuel B. Anyona, Qiuying Cheng, ... Douglas J. Perkins in Nature Communications
    Article Open access 12 June 2024
  6. SIGNET: transcriptome-wide causal inference for gene regulatory networks

    Gene regulation plays an important role in understanding the mechanisms of human biology and diseases. However, inferring causal relationships...

    Zhongli Jiang, Chen Chen, ... Dabao Zhang in Scientific Reports
    Article Open access 08 November 2023
  7. Reference-free assembly of long-read transcriptome sequencing data with RNA-Bloom2

    Long-read sequencing technologies have improved significantly since their emergence. Their read lengths, potentially spanning entire transcripts, is...

    Ka Ming Nip, Saber Hafezqorani, ... Inanc Birol in Nature Communications
    Article Open access 22 May 2023
  8. Spatial epigenome–transcriptome co-profiling of mammalian tissues

    Emerging spatial technologies, including spatial transcriptomics and spatial epigenomics, are becoming powerful tools for profiling of cellular...

    Di Zhang, Yanxiang Deng, ... Rong Fan in Nature
    Article Open access 15 March 2023
  9. Direct RNA sequencing coupled with adaptive sampling enriches RNAs of interest in the transcriptome

    Abundant cellular transcripts occupy most of the sequencing reads in the transcriptome, making it challenging to assay for low-abundant transcripts....

    Jiaxu Wang, Lin Yang, ... Yue Wan in Nature Communications
    Article Open access 11 January 2024
  10. Host nasopharyngeal transcriptome dataset of a SARS-CoV-2 positive Italian cohort

    The ongoing COVID-19 pandemic caused by SARS-CoV-2 has affected millions of people worldwide and has significant implications for public health. Host...

    Annamaria Salvati, Carlo Ferravante, ... Giorgio Giurato in Scientific Data
    Article Open access 14 June 2023
  11. Unsupervised analysis of whole transcriptome data from human pluripotent stem cells cardiac differentiation

    The main objective of the present work was to highlight differences and similarities in gene expression patterns between different pluripotent stem...

    Sofia P. Agostinho, Mariana A. Branco, ... Carlos A. V. Rodrigues in Scientific Reports
    Article Open access 07 February 2024
  12. Transcriptome profiling of aerial and subterranean peanut pod development

    Peanut ( Arachis hypogaea ) showcases geocarpic behavior, transitioning from aerial flowering to subterranean seed development. We recently obtained an...

    Zhenying Peng, Kai-Hua Jia, ... Shubo Wan in Scientific Data
    Article Open access 11 April 2024
  13. A multi-omics dataset of human transcriptome and proteome stable reference

    The development of high-throughput omics technology has greatly promoted the development of biomedicine. However, the poor reproducibility of omics...

    Shaohua Lu, Hong Lu, ... Gong Zhang in Scientific Data
    Article Open access 13 July 2023
  14. Incomplete transcripts dominate the Mycobacterium tuberculosis transcriptome

    Mycobacterium tuberculosis (Mtb) is a bacterial pathogen that causes tuberculosis (TB), an infectious disease that is responsible for major health...

    **angwu Ju, Shuqi Li, ... Shixin Liu in Nature
    Article Open access 28 February 2024
  15. Whole genome and transcriptome integrated analyses guide clinical care of pediatric poor prognosis cancers

    The role for routine whole genome and transcriptome analysis (WGTA) for poor prognosis pediatric cancers remains undetermined. Here, we characterize...

    Rebecca J. Deyell, Yaoqing Shen, ... Shahrad R. Rassekh in Nature Communications
    Article Open access 16 May 2024
  16. De novo transcriptome for Chiloscyllium griseum, a long-tail carpet shark of the Indian waters

    Sharks have thrived in the oceans for 400 million years, experienced five extinctions and evolved into today’s apex predators. However, enormous...

    Pooja Harshan, Sandhya Sukumaran, A. Gopalakrishnan in Scientific Data
    Article Open access 09 March 2024
  17. Transcriptome analysis and development of EST-SSR markers in the mushroom Auricularia heimuer

    Auricularia heimuer , the third most frequently cultivated edible mushroom species worldwide, has high medicinal value. However, a shortage of...

    Lihe Jiao, Chuang Han, ... Yunzhi Zhang in Scientific Reports
    Article Open access 29 May 2024
  18. Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice

    Thyroid hormones (THs) are important regulators of systemic energy metabolism. In the liver, they stimulate lipid and cholesterol turnover and...

    Leonardo Vinicius Monteiro de Assis, Lisbeth Harder, ... Henrik Oster in Scientific Reports
    Article Open access 05 January 2024
  19. Comparative transcriptome profiles of four sexually size dimorphic fish

    Sexual size dimorphism is widespread in fish species. Although sex growth differences in multiple species have been studied successively, the...

    Li-Fei Luo, Zi-Sheng Xu, ... Ze-**a Gao in Scientific Data
    Article Open access 17 December 2022
  20. Full-length transcriptome analysis of a bloom-forming dinoflagellate Prorocentrum shikokuense (Dinophyceae)

    Prorocentrum shikokuense (formerly P. donghaiense ) is a pivotal dinoflagellate species associating with the HABs in the East China Sea. The...

    **aohui Pan, Hang Liu, ... Guanpin Yang in Scientific Data
    Article Open access 25 April 2024
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