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Showing 1-20 of 5,551 results
  1. KRT13 and UPK1B for differential diagnosis between metastatic lung carcinoma from oral squamous cell carcinoma and lung squamous cell carcinoma

    Oral squamous cell carcinomas unusually show distant metastasis to the lung after primary treatment, which can be difficult to differentiate from...

    Hiroyuki Goda, Koh-ichi Nakashiro, ... Daisuke Uchida in Scientific Reports
    Article Open access 18 December 2023
  2. Average log change rate of pretreatment squamous cell carcinoma antigen after concurrent chemoradiotherapy in stage IIIC1 cervical squamous cell carcinoma

    We aimed to determine whether pretreatment squamous cell carcinoma antigen (SCC-Ag) levels and the average logarithmic change in SCC-Ag levels ( ...

    Oyeon Cho, Mison Chun, Suk-Joon Chang in Scientific Reports
    Article Open access 15 April 2024
  3. Eugenol as a potential adjuvant therapy for gingival squamous cell carcinoma

    Adoption of plant-derived compounds for the management of oral cancer is encouraged by the scientific community due to emerging chemoresistance and...

    Hawraa Issa, Lionel Loubaki, ... Abdelhabib Semlali in Scientific Reports
    Article Open access 13 May 2024
  4. NPLOC4 is a potential target and a poor prognostic signature in lung squamous cell carcinoma

    Few prognostic biomarkers exist for lung squamous cell carcinoma (LUSC), which has a poor five-year survival rate. Using bioinformatics, this study...

    Naixue Wang, Dantong Zhu, ... Zhendong Zheng in Scientific Reports
    Article Open access 22 November 2023
  5. A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinoma

    Basal cell carcinoma and squamous cell carcinoma are the most common skin cancers, and have genetic overlap with melanoma, pigmentation traits,...

    Mathias Seviiri, Matthew H. Law, ... Stuart MacGregor in Nature Communications
    Article Open access 10 December 2022
  6. miR-378a-5p exerts tumor-suppressive effects on esophageal squamous cell carcinoma after neoadjuvant immunotherapy by downregulating APOC1/CEP55

    Genetic assessment of tumors following neoadjuvant immunotherapy helps identifying targets that mediate anti-tumor immunity. In this study, we...

    Yang Pengjie, Jia Rong, Ning Pengfei in Scientific Reports
    Article Open access 03 January 2024
  7. Genomic profiles of Japanese patients with vulvar squamous cell carcinoma

    The incidence of vulvar carcinoma varies by race; however, it is a rare disease, and its genomic profiles remain largely unknown. This study examined...

    Erisa Fujii, Mayumi Kobayashi Kato, ... Hiroshi Yoshida in Scientific Reports
    Article Open access 06 June 2024
  8. Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma

    Chemo-activation of mitochondrial ClpP exhibits promising anticancer properties. However, we are currently unaware of any studies using selective and...

    Lin-Lin Zhou, Tao Zhang, ... Cai-Guang Yang in Nature Communications
    Article Open access 03 November 2023
  9. Effectiveness of deep learning classifiers in histopathological diagnosis of oral squamous cell carcinoma by pathologists

    The study aims to identify histological classifiers from histopathological images of oral squamous cell carcinoma using convolutional neural network...

    Shintaro Sukegawa, Sawako Ono, ... Minoru Miyake in Scientific Reports
    Article Open access 19 July 2023
  10. PAK4 inhibition augments anti-tumour effect by immunomodulation in oral squamous cell carcinoma

    Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumours, warranting novel treatments. Here, we examined the therapeutic...

    Danki Takatsuka, Hidetake Tachinami, ... Kei Tomihara in Scientific Reports
    Article Open access 18 June 2024
  11. Genetic and molecular characterization of metabolic pathway-based clusters in esophageal squamous cell carcinoma

    Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive types of squamous cell carcinoma and represents a significant proportion of...

    Ze Wang, Yuan Zhang, ... Ming Lu in Scientific Reports
    Article Open access 14 March 2024
  12. Cancer cell plasticity defines response to immunotherapy in cutaneous squamous cell carcinoma

    Immune checkpoint blockade (ICB) approaches have changed the therapeutic landscape for many tumor types. However, half of cutaneous squamous cell...

    Laura Lorenzo-Sanz, Marta Lopez-Cerda, ... Purificación Muñoz in Nature Communications
    Article Open access 24 June 2024
  13. Clinicopathologic characteristics of second primary squamous cell carcinoma in patients with nasopharyngeal carcinoma after intensity-modulated radiotherapy

    To compare the clinicopathologic characteristics of second primary squamous cell carcinoma (SPSCC) in patients with nasopharyngeal carcinoma (NPC)...

    ** Wang, Shunlan Wang, ... Zhuming Guo in Scientific Reports
    Article Open access 20 May 2023
  14. The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma

    The TINCR ( T erminal differentiation- I nduced N on- C oding R NA) gene is selectively expressed in epithelium tissues and is involved in the control of...

    Lucia Morgado-Palacin, Jessie A. Brown, ... Adolfo A. Ferrando in Nature Communications
    Article Open access 10 March 2023
  15. Incidence trends and spatial distributions of lung adenocarcinoma and squamous cell carcinoma in Taiwan

    Lung cancer is the second most common cancer in Taiwan. After Taiwan implemented the Tobacco Hazards Prevention Act in 1997, smoking rates declined....

    Hsin-I Liu, Chun-Ju Chiang, ... Wen-Chung Lee in Scientific Reports
    Article Open access 30 January 2023
  16. Multimodal analysis of cfDNA methylomes for early detecting esophageal squamous cell carcinoma and precancerous lesions

    Detecting early-stage esophageal squamous cell carcinoma (ESCC) and precancerous lesions is critical for improving survival. Here, we conduct...

    Jiaqi Liu, Lijun Dai, ... Zhihua Liu in Nature Communications
    Article Open access 02 May 2024
  17. Functionally distinct cancer-associated fibroblast subpopulations establish a tumor promoting environment in squamous cell carcinoma

    Cutaneous squamous cell carcinoma (cSCC) is a serious public health problem due to its high incidence and metastatic potential. It may progress from...

    Sabrina Schütz, Llorenç Solé-Boldo, ... Frank Lyko in Nature Communications
    Article Open access 05 September 2023
  18. Overall survival and short-term efficacy analysis of cervical squamous cell carcinoma with skeletal muscle and 18F-FDG PET/CT parameters

    2-[ 18 F]fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography ( 18 F-FDG PET/CT) can provide tumor biological metabolism and...

    Junyu Zhang, Siyu Niu, ... Haiyan Liu in Scientific Reports
    Article Open access 27 February 2024
  19. Targeting the ZMIZ1-Notch1 signaling axis for the treatment of tongue squamous cell carcinoma

    Zinc finger MIZ-type containing 1 (ZMIZ1) is a transcriptional coactivator related to the protein inhibitors of activated STATs (PIAS) family....

    Yunqing Pang, Yunjie Sun, ... **g Wang in Scientific Reports
    Article Open access 12 June 2024
  20. Oral Lichen Planus and Oral Squamous Cell Carcinoma share key oncogenic signatures

    To investigate similarities in the gene profile of Oral Lichen Planus and Oral Squamous Cell Carcinoma that may justify a carcinogenic potential, we...

    Cristóvão Antunes de Lanna, Beatriz Nascimento Monteiro da Silva, ... Daniel Cohen Goldemberg in Scientific Reports
    Article Open access 30 November 2022
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