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Spindle-locked ripples mediate memory reactivation during human NREM sleep
Memory consolidation relies in part on the reactivation of previous experiences during sleep. The precise interplay of sleep-related oscillations...
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Sleep loss diminishes hippocampal reactivation and replay
Memories benefit from sleep
1 , and the reactivation and replay of waking experiences during hippocampal sharp-wave ripples (SWRs) are considered to be...
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Respiration modulates sleep oscillations and memory reactivation in humans
The beneficial effect of sleep on memory consolidation relies on the precise interplay of slow oscillations and spindles. However, whether these...
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The nucleic acid binding protein SFPQ represses EBV lytic reactivation by promoting histone H1 expression
Epstein-Barr virus (EBV) uses a biphasic lifecycle of latency and lytic reactivation to infect >95% of adults worldwide. Despite its central role in...
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Comparing targeted memory reactivation during slow wave sleep and sleep stage 2
Sleep facilitates declarative memory consolidation, which is assumed to rely on the reactivation of newly encoded memories orchestrated by the...
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Barrier-to-autointegration factor 1 promotes gammaherpesvirus reactivation from latency
Gammaherpesviruses, including Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV), are DNA viruses that are globally associated...
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Controls on fracture openness and reactivation in Forsmark, Sweden
In crystalline bedrock, the open fraction of the fracture network constitutes the main pathways for fluids. Many observations point out that the...
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Reactivation of a somatic errantivirus and germline invasion in Drosophila ovaries
Most Drosophila transposable elements are LTR retrotransposons, some of which belong to the genus Errantivirus and share structural and functional...
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Reactivation-induced motor skill modulation does not operate at a rapid micro-timescale level
Abundant evidence shows that consolidated memories are susceptible to modifications following their reactivation. Processes of memory consolidation...
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UVB induced reactivation leads to HSV1 in the corneas of virtually all latently infected mice and requires STING to develop corneal disease
Reactivation of latent herpes simplex type 1 results in virus returning to the cornea leading to recurrent herpetic stromal keratitis (rHSK). We...
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Cycles of goal silencing and reactivation underlie complex problem-solving in primate frontal and parietal cortex
While classic views proposed that working memory (WM) is mediated by sustained firing, recent evidence suggests a contribution of activity-silent...
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Risk factors associated with cytomegalovirus reactivation in patients receiving immunosuppressive therapy for rheumatic diseases: a retrospective study
Immunosuppressive treatment is a common cause of cytomegalovirus (CMV) reactivation. However, there is no consensus regarding the risk factors for...
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Inducing forgetting of unwanted memories through subliminal reactivation
Processes that might facilitate the forgetting of unwanted experiences typically require the actual or imagined re-exposure to reminders of the...
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Age-associated B cells are long-lasting effectors that impede latent γHV68 reactivation
Age-associated B cells (ABCs; CD19 + CD11c + T-bet + ) are a unique population that are increased in an array of viral infections, though their role during...
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Immunoprofiling reveals cell subsets associated with the trajectory of cytomegalovirus reactivation post stem cell transplantation
Human cytomegalovirus reactivation is a major opportunistic infection after allogeneic haematopoietic stem cell transplantation and has a complex...
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NAT10-dependent N4‐acetylcytidine modification mediates PAN RNA stability, KSHV reactivation, and IFI16-related inflammasome activation
N -acetyltransferase 10 (NAT10) is an N 4 ‐acetylcytidine (ac 4 C) writer that catalyzes RNA acetylation at cytidine N 4 position on tRNAs, rRNAs and...
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Serum IL-1β predicts de novo hepatitis B virus reactivation during direct-acting antiviral therapy for hepatitis C, not during anti-cancer/immunosuppressive therapy
De novo hepatitis B virus (HBV) reactivation occurs during direct-acting antiviral (DAA) treatment in hepatitis C virus (HCV)-infected patients with...
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Identification of redox activators for continuous reactivation of glyoxal oxidase from Trametes versicolor in a two-enzyme reaction cascade
Glyoxal oxidases, belonging to the group of copper radical oxidases (CROs), oxidize aldehydes to carboxylic acids, while reducing O 2 to H 2 O 2 . Their...
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Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis
MAPK pathway-driven tumorigenesis, often induced by BRAF V600E , relies on epithelial dedifferentiation. However, how lineage differentiation events...
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Impact of IL-15 and latency reversing agent combinations in the reactivation and NK cell-mediated suppression of the HIV reservoir
Inhibitors of histone deacetylases (HDACis) are major latency reversing agent (LRA) candidates in ‘shock and kill’ strategies to eradicate the HIV...
