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Silica nanolayer coated capillary by hydrothermal sol–gel process for amines separation and detection of tyramine in food products
A hydrothermal sol–gel method for reproducible formation of silica nanolayer on the wall of silica capillaries was developed for...
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The localization of amyloid precursor protein to ependymal cilia in vertebrates and its role in ciliogenesis and brain development in zebrafish
Amyloid precursor protein (APP) is expressed in many tissues in human, mice and in zebrafish. In zebrafish, there are two orthologues, Appa and Appb....
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Behavioral roles of biogenic amines in bumble bee males
To compare the behavioral roles of biogenic amines in the males of primitive and advanced eusocial bees, we determined the levels of dopamine- and...
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Metabolomics of early blight (Alternaria solani) susceptible tomato (Solanum lycopersicum) unfolds key biomarker metabolites and involved metabolic pathways
Tomato ( Solanum lycopersicum ) is among the most important commercial horticultural crops worldwide. The crop quality and production is largely...
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Ultra-high performance liquid chromatography high-resolution mass spectrometry for metabolomic analysis of dental calculus from Duke Alessandro Farnese and Maria D’Aviz
Dental calculus is a valuable resource for the reconstruction of dietary habits and oral microbiome of past populations. In 2020 the remains of Duke...
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Positive-charge tuned gelatin hydrogel-siSPARC injectable for siRNA anti-scarring therapy in post glaucoma filtration surgery
Small interfering RNA (siRNA) therapy is a promising epigenetic silencing strategy. However, its widespread adoption has been severely impeded by its...
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Biochemical characterization of Dimocarpus longan polyphenol oxidase provides insights into its catalytic efficiency
The “dragon-eye” fruits produced by the tropical longan tree are rich in nutrients and antioxidants. They suffer from post-harvest enzymatic...
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Starter culture-related changes in free amino acids, biogenic amines profile, and antioxidant properties of fermented red beetroot grown in Poland
Fermentation of two red beet cultivars (Wodan and Alto) with single-strain starter cultures consisting of selected strains of lactic acid bacteria...
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The monoaminergic system is a bilaterian innovation
Monoamines like serotonin, dopamine, and adrenaline/noradrenaline (epinephrine/norepinephrine) act as neuromodulators in the nervous system. They...
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Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme
A major challenge to achieving industry-scale biomanufacturing of therapeutic alkaloids is the slow process of biocatalyst engineering....
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Kinetic study on the reaction of sodium nitrite with neurotransmitters secreted in the stomach
Nitroso-compounds are potentially mutagenic and carcinogenic compounds due to their ability to alkylate DNA bases. One of the most common sources of...
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Relationship between indirect genetic effects for growth, environmental enrichment, co** style and sex with the serum metabolome profile of pigs
Including Indirect Genetic Effects (IGE) in breeding programs to reduce aggression in group housed animals has been proposed. However, the effect of...
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Multiomic interpretation of fungus-infected ant metabolomes during manipulated summit disease
Camponotus floridanus ants show altered behaviors followed by a fatal summiting phenotype when infected with manipulating Ophiocordyceps...
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Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators
Eggerthella lenta is a prevalent human gut Actinobacterium implicated in drug, dietary phytochemical, and bile acid metabolism and associated with...
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Ortholog genes from cactophilic Drosophila provide insight into human adaptation to hallucinogenic cacti
Cultural transformations of lifestyles and dietary practices have been key drivers of human evolution. However, while most of the evidence of genomic...
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A novel pathway of levodopa metabolism by commensal Bifidobacteria
The gold-standard treatment for Parkinson’s disease is levodopa (L-DOPA), which is taken orally and absorbed intestinally. L-DOPA must reach the...
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Construction and characterization of a double mutant of Enterococcus faecalis that does not produce biogenic amines
Enterococcus faecalis is a lactic acid bacterium characterized by its tolerance of very diverse environmental conditions, a property that allows it...
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Bumble bee queens activate dopamine production and gene expression in nutritional signaling pathways in the brain
To explore the neuroendocrine mechanisms underlying caste-specific behavior and its evolution from primitive to advanced eusocial bees, the monoamine...
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Cell type diversity in a develo** octopus brain
Octopuses are mollusks that have evolved intricate neural systems comparable with vertebrates in terms of cell number, complexity and size. The brain...
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Mass production of lumenogenic human embryoid bodies and functional cardiospheres using in-air-generated microcapsules
Organoids are engineered 3D miniature tissues that are defined by their organ-like structures, which drive a fundamental understanding of human...