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Intraparotid lymph node metastasis affects distant metastasis in parotid adenoid cystic carcinoma
To evaluate the relationship between factors of metastatic intraparotid lymph node (IPLN) and distant metastasis in parotid adenoid cystic carcinoma...
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Hyaluronidase inhibitor delphinidin inhibits cancer metastasis
Cancer remains a formidable global health challenge, with metastasis being a key contributor to its lethality. Abundant high molecular mass...
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Aneuploid embryonic stem cells drive teratoma metastasis
Aneuploidy, a deviation of the chromosome number from euploidy, is one of the hallmarks of cancer. High levels of aneuploidy are generally correlated...
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Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis
Metastasis is the major cause of lung cancer-related death, but the mechanisms governing lung tumor metastasis remain incompletely elucidated. SE...
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Decoding the interplay between genetic and non-genetic drivers of metastasis
Metastasis is a multistep process by which cancer cells break away from their original location and spread to distant organs, and is responsible for...
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Prediction of hepatic metastasis in esophageal cancer based on machine learning
This study aimed to establish a machine learning (ML) model for predicting hepatic metastasis in esophageal cancer. We retrospectively analyzed...
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Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
MALAT1, one of the few highly conserved nuclear long noncoding RNAs (lncRNAs), is abundantly expressed in normal tissues. Previously, targeted...
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Preoperatively predicting the lymph node metastasis and prognosis for gastric cancer patients
The preoperative distinguishment of lymph nodes (LN) with metastasis plays a pivotal role in guiding the surgical extension for gastric cancer (GC)....
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Unveiling breast cancer metastasis through an advanced X-ray imaging approach
Breast cancer is a significant global health burden, causing a substantial number of deaths. Systemic metastatic tumour cell dissemination is a major...
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Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice
Although macrophages contribute to cancer cell dissemination, immune evasion, and metastatic outgrowth, they have also been reported to coordinate...
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Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis
The metastasis-invasion cascade describes the series of steps required for a cancer cell to successfully spread from its primary tumor and ultimately...
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SOCS2 inhibits hepatoblastoma metastasis via downregulation of the JAK2/STAT5 signal pathway
Metastasis of hepatoblastoma (HB) is a key factor that impairs the prognosis and treatment of children. The suppressor of cytokine signaling 2...
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Evolutionary route of nasopharyngeal carcinoma metastasis and its clinical significance
It is critical to understand factors associated with nasopharyngeal carcinoma (NPC) metastasis. To track the evolutionary route of metastasis, here...
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Predicting diagnosis and survival of bone metastasis in breast cancer using machine learning
This study aimed at establishing more accurate predictive models based on novel machine learning algorithms, with the overarching goal of providing...
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Clinical features and treatment outcomes of intraocular and ocular adnexal metastasis
The aim of this study was to investigate the primary sites, clinical characteristics, and treatment outcomes of patients with metastatic tumors in...
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Construction of a nomogram for predicting HNSCC distant metastasis and identification of EIF5A as a hub gene
Patients with distant metastasis of head and neck squamous cell carcinoma (HNSCC) often have a poor prognosis. However, early diagnosis of distant...
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Metabolic dependencies of metastasis-initiating cells in female breast cancer
Understanding the mechanisms that enable cancer cells to metastasize is essential in preventing cancer progression. Here we examine the metabolic...
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Mutation characteristics and molecular evolution of ovarian metastasis from gastric cancer and potential biomarkers for paclitaxel treatment
Ovarian metastasis is one of the major causes of treatment failure in patients with gastric cancer (GC). However, the genomic characteristics of...
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HAPLN1 potentiates peritoneal metastasis in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) frequently metastasizes into the peritoneum, which contributes to poor prognosis. Metastatic spreading is...
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Downregulation of osteoprotegerin in colorectal cancer cells promotes liver metastasis via activating tumor-associated macrophage
Osteoprotegerin (OPG) is a secreted cytokine that functions as a decoy receptor for receptor activator of nuclear factor kappa-B (RANK) ligand...
