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Suggested Case of Langerhans Cell Histiocytosis in a Cretaceous dinosaur
Susceptibility to diseases is common to humans and dinosaurs. Since much of the biological history of every living creature is shaped by its...
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Altered Populations of Unconventional T Cell Lineages in Patients with Langerhans Cell Histiocytosis
Langerhans cell histiocytosis (LCH) lesions are defined by the presence of CD1a + /CD207 + myeloid cells, but many other immune cells are present...
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Comparison of whole-body MRI, bone scan, and radiographic skeletal survey for lesion detection and risk stratification of Langerhans Cell Histiocytosis
Accurate risk stratification according to the extent of Langerhans cell histiocytosis (LCH) determined on whole-body evaluation is important for...
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Ultrasound performance in pediatric deep soft-tissue tumor characterization
This study investigated the performance of ultrasonography in diagnosing deep soft-tissue tumors and tumor-like lesions in children with histological...
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Studies on anti-rabphilin-3A antibodies in 15 consecutive patients presenting with central diabetes insipidus at a single referral center
Central diabetes insipidus (CDI) is a rare condition caused by various underlying diseases including inflammatory and autoimmune diseases, and...
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The appropriate and sequential value of standard radiograph, computed tomography and magnetic resonance imaging to characterize a bone tumor
Radiographs (XR), computed tomography (CT) or magnetic resonance imaging (MRI) are regularly analyzed to determine whether a bone lesion is benign or...
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Shared and distinct genetic etiologies for different types of clonal hematopoiesis
Clonal hematopoiesis (CH)—age-related expansion of mutated hematopoietic clones—can differ in frequency and cellular fitness by CH type (e.g.,...
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AI co-pilot: content-based image retrieval for the reading of rare diseases in chest CT
The aim of the study was to evaluate the impact of the newly developed Similar patient search (SPS) Web Service, which supports reading complex lung...
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Unlocking multidimensional cancer therapeutics using geometric data science
Personalised approaches to cancer therapeutics primarily involve identification of patient sub-populations most likely to benefit from targeted...
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The transnasal endoscopic approach for resection of clival tumors: a single-center experience
Clival tumors present challenging entities regarding their treatment options. Due to their proximity to critical neurovascular structures, the...
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The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers
The efficacy of the highly selective RET inhibitor selpercatinib is now established in RET -driven cancers, and we sought to characterize the...
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Sarcoma classification by DNA methylation profiling
Sarcomas are malignant soft tissue and bone tumours affecting adults, adolescents and children. They represent a morphologically heterogeneous class...
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Study on intestinal parasitic infections and gut microbiota in cancer patients at a tertiary teaching hospital in Malaysia
Intestinal parasitic infections (IPIs) can lead to significant morbidity and mortality in cancer patients. While they are unlikely to cause severe...
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Real-life prevalence of progressive fibrosing interstitial lung diseases
The concept of progressive fibrosing interstitial lung disease (PF-ILD) has recently emerged. However, real-life proportion of PF-ILDs outside IPF is...
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A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant
The goals of the current study were to evaluate audibility and cortical speech processing, and to provide insight into binaural processing in...
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New insights on familial colorectal cancer type X syndrome
Familial colorectal cancer type X (FCCTX) is a heterogeneous colorectal cancer predisposition syndrome that, although displays a cancer pattern...
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Efficacy of MEK inhibition in patients with histiocytic neoplasms
Histiocytic neoplasms are a heterogeneous group of clonal haematopoietic disorders that are marked by diverse mutations in the mitogen-activated...
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Langerhans cell histiocytosis in the adult lumbar spine: case report
IntroductionLangerhans cell histiocytosis (LCH) occurs rarely in the spine of adults. The radiological findings usually resemble vertebral tumors....
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Robust deep learning classification of adamantinomatous craniopharyngioma from limited preoperative radiographic images
Deep learning (DL) is a widely applied mathematical modeling technique. Classically, DL models utilize large volumes of training data, which are not...
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Increased 18F-FDG signal recovery from small physiological structures in digital PET/CT and application to the pituitary gland
On conventional PET/CT, and under physiological conditions, the volume of the pituitary gland (PG) is small, and its metabolic activity is commonly...
